These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 22691706)

  • 1. Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II.
    Fisher Z; Boone CD; Biswas SM; Venkatakrishnan B; Aggarwal M; Tu C; Agbandje-McKenna M; Silverman D; McKenna R
    Protein Eng Des Sel; 2012 Jul; 25(7):347-55. PubMed ID: 22691706
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and catalytic characterization of a thermally stable and acid-stable variant of human carbonic anhydrase II containing an engineered disulfide bond.
    Boone CD; Habibzadegan A; Tu C; Silverman DN; McKenna R
    Acta Crystallogr D Biol Crystallogr; 2013 Aug; 69(Pt 8):1414-22. PubMed ID: 23897465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II.
    Boone CD; Rasi V; Tu C; McKenna R
    FEBS J; 2015 Apr; 282(8):1445-57. PubMed ID: 25683338
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
    Pinard MA; Boone CD; Rife BD; Supuran CT; McKenna R
    Bioorg Med Chem; 2013 Nov; 21(22):7210-5. PubMed ID: 24090602
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II.
    Fisher SZ; Tu C; Bhatt D; Govindasamy L; Agbandje-McKenna M; McKenna R; Silverman DN
    Biochemistry; 2007 Mar; 46(12):3803-13. PubMed ID: 17330962
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure and kinetic studies of a tetrameric type II β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
    Ferraroni M; Del Prete S; Vullo D; Capasso C; Supuran CT
    Acta Crystallogr D Biol Crystallogr; 2015 Dec; 71(Pt 12):2449-56. PubMed ID: 26627652
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase II.
    Mikulski R; Avvaru BS; Tu C; Case N; McKenna R; Silverman DN
    Arch Biochem Biophys; 2011 Feb; 506(2):181-7. PubMed ID: 21145876
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights into a thermostable variant of human carbonic anhydrase II.
    Kean KM; Porter JJ; Mehl RA; Karplus PA
    Protein Sci; 2018 Feb; 27(2):573-577. PubMed ID: 29139171
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural, catalytic and stabilizing consequences of aromatic cluster variants in human carbonic anhydrase II.
    Boone CD; Gill S; Tu C; Silverman DN; McKenna R
    Arch Biochem Biophys; 2013 Nov; 539(1):31-7. PubMed ID: 24036123
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of active-site mutation at Asn67 on the proton transfer mechanism of human carbonic anhydrase II.
    Maupin CM; Zheng J; Tu C; McKenna R; Silverman DN; Voth GA
    Biochemistry; 2009 Aug; 48(33):7996-8005. PubMed ID: 19634894
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa.
    Pinard MA; Lotlikar SR; Boone CD; Vullo D; Supuran CT; Patrauchan MA; McKenna R
    Bioorg Med Chem; 2015 Aug; 23(15):4831-4838. PubMed ID: 26068018
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Water networks in fast proton transfer during catalysis by human carbonic anhydrase II.
    Mikulski R; West D; Sippel KH; Avvaru BS; Aggarwal M; Tu C; McKenna R; Silverman DN
    Biochemistry; 2013 Jan; 52(1):125-31. PubMed ID: 23215152
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure and catalysis by carbonic anhydrase II: role of active-site tryptophan 5.
    Mikulski R; Domsic JF; Ling G; Tu C; Robbins AH; Silverman DN; McKenna R
    Arch Biochem Biophys; 2011 Dec; 516(2):97-102. PubMed ID: 22001224
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural and kinetic effects on changes in the CO(2) binding pocket of human carbonic anhydrase II.
    West D; Kim CU; Tu C; Robbins AH; Gruner SM; Silverman DN; McKenna R
    Biochemistry; 2012 Nov; 51(45):9156-63. PubMed ID: 23098192
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II.
    Zheng J; Avvaru BS; Tu C; McKenna R; Silverman DN
    Biochemistry; 2008 Nov; 47(46):12028-36. PubMed ID: 18942852
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II.
    Fisher Z; Hernandez Prada JA; Tu C; Duda D; Yoshioka C; An H; Govindasamy L; Silverman DN; McKenna R
    Biochemistry; 2005 Feb; 44(4):1097-105. PubMed ID: 15667203
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neutron structure of human carbonic anhydrase II: implications for proton transfer.
    Fisher SZ; Kovalevsky AY; Domsic JF; Mustyakimov M; McKenna R; Silverman DN; Langan PA
    Biochemistry; 2010 Jan; 49(3):415-21. PubMed ID: 20025241
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II-acetazolamide complex.
    Aggarwal M; Boone CD; Kondeti B; Tu C; Silverman DN; McKenna R
    Acta Crystallogr D Biol Crystallogr; 2013 May; 69(Pt 5):860-5. PubMed ID: 23633596
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and biophysical characterization of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration.
    Díaz-Torres NA; Mahon BP; Boone CD; Pinard MA; Tu C; Ng R; Agbandje-McKenna M; Silverman D; Scott K; McKenna R
    Acta Crystallogr D Biol Crystallogr; 2015 Aug; 71(Pt 8):1745-56. PubMed ID: 26249355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and kinetic study of the extended active site for proton transfer in human carbonic anhydrase II.
    Domsic JF; Williams W; Fisher SZ; Tu C; Agbandje-McKenna M; Silverman DN; McKenna R
    Biochemistry; 2010 Aug; 49(30):6394-9. PubMed ID: 20578724
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.