BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 22693251)

  • 1. Functional interaction of tumor suppressor DLC1 and caveolin-1 in cancer cells.
    Du X; Qian X; Papageorge A; Schetter AJ; Vass WC; Liu X; Braverman R; Robles AI; Lowy DR
    Cancer Res; 2012 Sep; 72(17):4405-16. PubMed ID: 22693251
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1.
    Sanchez-Solana B; Wang D; Qian X; Velayoudame P; Simanshu DK; Acharya JK; Lowy DR
    Mol Cancer; 2021 Nov; 20(1):141. PubMed ID: 34727930
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth.
    Kim TY; Jackson S; Xiong Y; Whitsett TG; Lobello JR; Weiss GJ; Tran NL; Bang YJ; Der CJ
    Proc Natl Acad Sci U S A; 2013 Oct; 110(42):16868-73. PubMed ID: 24082123
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cancer-Associated Point Mutations in the
    Wang D; Qian X; Sanchez-Solana B; Tripathi BK; Durkin ME; Lowy DR
    Cancer Res; 2020 Sep; 80(17):3568-3579. PubMed ID: 32606003
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inactivation of the Dlc1 gene cooperates with downregulation of p15INK4b and p16Ink4a, leading to neoplastic transformation and poor prognosis in human cancer.
    Qian X; Durkin ME; Wang D; Tripathi BK; Olson L; Yang XY; Vass WC; Popescu NC; Lowy DR
    Cancer Res; 2012 Nov; 72(22):5900-11. PubMed ID: 23010077
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rho GTPase-activating protein deleted in liver cancer suppresses cell proliferation and invasion in hepatocellular carcinoma.
    Wong CM; Yam JW; Ching YP; Yau TO; Leung TH; Jin DY; Ng IO
    Cancer Res; 2005 Oct; 65(19):8861-8. PubMed ID: 16204057
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DLC1 interaction with S100A10 mediates inhibition of in vitro cell invasion and tumorigenicity of lung cancer cells through a RhoGAP-independent mechanism.
    Yang X; Popescu NC; Zimonjic DB
    Cancer Res; 2011 Apr; 71(8):2916-25. PubMed ID: 21372205
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DLC1 SAM domain-binding peptides inhibit cancer cell growth and migration by inactivating RhoA.
    Joshi R; Qin L; Cao X; Zhong S; Voss C; Min W; Li SSC
    J Biol Chem; 2020 Jan; 295(2):645-656. PubMed ID: 31806702
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of Dlc1 isoform 2 in K-Ras2(G12D) induced thymic cancer.
    Sabbir MG; Prieditis H; Ravinsky E; Mowat MR
    PLoS One; 2012; 7(7):e40302. PubMed ID: 22792269
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK).
    Li G; Du X; Vass WC; Papageorge AG; Lowy DR; Qian X
    Proc Natl Acad Sci U S A; 2011 Oct; 108(41):17129-34. PubMed ID: 21969587
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GAP-independent functions of DLC1 in metastasis.
    Barras D; Widmann C
    Cancer Metastasis Rev; 2014 Mar; 33(1):87-100. PubMed ID: 24338004
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of deleted in liver cancer 1 tumor suppressor by protein-protein interactions and phosphorylation.
    Ko FC; Ping Yam JW
    Int J Cancer; 2014 Jul; 135(2):264-9. PubMed ID: 24114040
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The tumor suppressor protein DLC1 is regulated by PKD-mediated GAP domain phosphorylation.
    Scholz RP; Gustafsson JO; Hoffmann P; Jaiswal M; Ahmadian MR; Eisler SA; Erlmann P; Schmid S; Hausser A; Olayioye MA
    Exp Cell Res; 2011 Feb; 317(4):496-503. PubMed ID: 21087603
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fluctuation of ROS regulates proliferation and mediates inhibition of migration by reducing the interaction between DLC1 and CAV-1 in breast cancer cells.
    Yang B; Zhu W; Zheng Z; Chai R; Ji S; Ren G; Liu T; Liu Z; Song T; Li F; Liu S; Li G
    In Vitro Cell Dev Biol Anim; 2017 Apr; 53(4):354-362. PubMed ID: 28130753
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A tumor suppressor DLC1: The functions and signal pathways.
    Zhang Y; Li G
    J Cell Physiol; 2020 Jun; 235(6):4999-5007. PubMed ID: 31773748
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nuclear-targeted deleted in liver cancer 1 (DLC1) is less efficient in exerting its tumor suppressive activity both in vitro and in vivo.
    Chan LK; Ko FC; Sze KM; Ng IO; Yam JW
    PLoS One; 2011; 6(9):e25547. PubMed ID: 21966542
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tumor suppressor gene DLC1: Its modifications, interactive molecules, and potential prospects for clinical cancer application.
    Ren G; Li G
    Int J Biol Macromol; 2021 Jul; 182():264-275. PubMed ID: 33836193
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Quantitative phosphoproteomic analysis identifies novel functional pathways of tumor suppressor DLC1 in estrogen receptor positive breast cancer.
    Gökmen-Polar Y; True JD; Vieth E; Gu Y; Gu X; Qi GD; Mosley AL; Badve SS
    PLoS One; 2018; 13(10):e0204658. PubMed ID: 30278072
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1.
    Tripathi BK; Grant T; Qian X; Zhou M; Mertins P; Wang D; Papageorge AG; Tarasov SG; Hunter KW; Carr SA; Lowy DR
    J Cell Biol; 2017 Dec; 216(12):4255-4270. PubMed ID: 29114068
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities.
    Qian X; Li G; Asmussen HK; Asnaghi L; Vass WC; Braverman R; Yamada KM; Popescu NC; Papageorge AG; Lowy DR
    Proc Natl Acad Sci U S A; 2007 May; 104(21):9012-7. PubMed ID: 17517630
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.