BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 22696657)

  • 1. Safer, silencing-resistant lentiviral vectors: optimization of the ubiquitous chromatin-opening element through elimination of aberrant splicing.
    Knight S; Zhang F; Mueller-Kuller U; Bokhoven M; Gupta A; Broughton T; Sha S; Antoniou MN; Brendel C; Grez M; Thrasher AJ; Collins M; Takeuchi Y
    J Virol; 2012 Sep; 86(17):9088-95. PubMed ID: 22696657
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Physiological regulation of transgene expression by a lentiviral vector containing the A2UCOE linked to a myeloid promoter.
    Brendel C; Müller-Kuller U; Schultze-Strasser S; Stein S; Chen-Wichmann L; Krattenmacher A; Kunkel H; Dillmann A; Antoniou MN; Grez M
    Gene Ther; 2012 Oct; 19(10):1018-29. PubMed ID: 22071971
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation-mediated silencing of lentiviral vectors.
    Zhang F; Frost AR; Blundell MP; Bales O; Antoniou MN; Thrasher AJ
    Mol Ther; 2010 Sep; 18(9):1640-9. PubMed ID: 20588258
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells.
    Zhang F; Thornhill SI; Howe SJ; Ulaganathan M; Schambach A; Sinclair J; Kinnon C; Gaspar HB; Antoniou M; Thrasher AJ
    Blood; 2007 Sep; 110(5):1448-57. PubMed ID: 17456723
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Efficiency of different fragment lengths of the ubiquitous chromatin opening element HNRPA2B1-CBX3 in driving human CD18 gene expression within self-inactivating lentiviral vectors for gene therapy applications.
    Gopinath C; Chodisetty S; Ghosh A; Nelson EJR
    Gene; 2019 Aug; 710():265-272. PubMed ID: 31200085
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Long-term reproducible expression in human fetal liver hematopoietic stem cells with a UCOE-based lentiviral vector.
    Dighe N; Khoury M; Mattar C; Chong M; Choolani M; Chen J; Antoniou MN; Chan JK
    PLoS One; 2014; 9(8):e104805. PubMed ID: 25118036
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sustained and regulated gene expression by Tet-inducible "all-in-one" retroviral vectors containing the HNRPA2B1-CBX3 UCOE
    Cullmann K; Blokland KEC; Sebe A; Schenk F; Ivics Z; Heinz N; Modlich U
    Biomaterials; 2019 Feb; 192():486-499. PubMed ID: 30508767
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lentiviral MGMT(P140K)-mediated in vivo selection employing a ubiquitous chromatin opening element (A2UCOE) linked to a cellular promoter.
    Phaltane R; Lachmann N; Brennig S; Ackermann M; Modlich U; Moritz T
    Biomaterials; 2014 Aug; 35(25):7204-13. PubMed ID: 24875758
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interplay of Promoter Usage and Intragenic CpG Content: Impact on GFP Reporter Gene Expression.
    Krinner S; Heitzer A; Asbach B; Wagner R
    Hum Gene Ther; 2015 Dec; 26(12):826-40. PubMed ID: 26414116
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny.
    Pfaff N; Lachmann N; Ackermann M; Kohlscheen S; Brendel C; Maetzig T; Niemann H; Antoniou MN; Grez M; Schambach A; Cantz T; Moritz T
    Stem Cells; 2013 Mar; 31(3):488-99. PubMed ID: 23307570
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insertional gene activation by lentiviral and gammaretroviral vectors.
    Bokhoven M; Stephen SL; Knight S; Gevers EF; Robinson IC; Takeuchi Y; Collins MK
    J Virol; 2009 Jan; 83(1):283-94. PubMed ID: 18945765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of a core region in the A2UCOE that confers effective anti-silencing activity.
    Zhang F; Santilli G; Thrasher AJ
    Sci Rep; 2017 Aug; 7(1):10213. PubMed ID: 28860464
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The CpG-sites of the CBX3 ubiquitous chromatin opening element are critical structural determinants for the anti-silencing function.
    Kunkiel J; Gödecke N; Ackermann M; Hoffmann D; Schambach A; Lachmann N; Wirth D; Moritz T
    Sci Rep; 2017 Aug; 7(1):7919. PubMed ID: 28801671
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy.
    Ackermann M; Lachmann N; Hartung S; Eggenschwiler R; Pfaff N; Happle C; Mucci A; Göhring G; Niemann H; Hansen G; Schambach A; Cantz T; Zweigerdt R; Moritz T
    Biomaterials; 2014 Feb; 35(5):1531-42. PubMed ID: 24290698
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biosafety challenges for use of lentiviral vectors in gene therapy.
    Rothe M; Modlich U; Schambach A
    Curr Gene Ther; 2013 Dec; 13(6):453-68. PubMed ID: 24195603
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.
    Müller-Kuller U; Ackermann M; Kolodziej S; Brendel C; Fritsch J; Lachmann N; Kunkel H; Lausen J; Schambach A; Moritz T; Grez M
    Nucleic Acids Res; 2015 Feb; 43(3):1577-92. PubMed ID: 25605798
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generation of human induced pluripotent stem cells bearing an anti-HIV transgene by a lentiviral vector carrying an internal murine leukemia virus promoter.
    Kamata M; Liu S; Liang M; Nagaoka Y; Chen IS
    Hum Gene Ther; 2010 Nov; 21(11):1555-67. PubMed ID: 20524893
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chromatin function modifying elements in an industrial antibody production platform--comparison of UCOE, MAR, STAR and cHS4 elements.
    Saunders F; Sweeney B; Antoniou MN; Stephens P; Cain K
    PLoS One; 2015; 10(4):e0120096. PubMed ID: 25849659
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Detailed comparison of retroviral vectors and promoter configurations for stable and high transgene expression in human induced pluripotent stem cells.
    Hoffmann D; Schott JW; Geis FK; Lange L; Müller FJ; Lenz D; Zychlinski D; Steinemann D; Morgan M; Moritz T; Schambach A
    Gene Ther; 2017 May; 24(5):298-307. PubMed ID: 28346436
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Correlation of DNA methylation with histone modifications across the HNRPA2B1-CBX3 ubiquitously-acting chromatin open element (UCOE).
    Lindahl Allen M; Antoniou M
    Epigenetics; 2007; 2(4):227-36. PubMed ID: 18032920
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.