These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 22698498)

  • 1. Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles.
    Mandadapu SR; Weerawarna PM; Gunnam MR; Alliston KR; Lushington GH; Kim Y; Chang KO; Groutas WC
    Bioorg Med Chem Lett; 2012 Jul; 22(14):4820-6. PubMed ID: 22698498
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors.
    Mandadapu SR; Gunnam MR; Tiew KC; Uy RA; Prior AM; Alliston KR; Hua DH; Kim Y; Chang KO; Groutas WC
    Bioorg Med Chem Lett; 2013 Jan; 23(1):62-5. PubMed ID: 23218713
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics.
    Mandadapu SR; Gunnam MR; Galasiti Kankanamalage AC; Uy RA; Alliston KR; Lushington GH; Kim Y; Chang KO; Groutas WC
    Bioorg Med Chem Lett; 2013 Nov; 23(21):5941-4. PubMed ID: 24054123
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease.
    Damalanka VC; Kim Y; Galasiti Kankanamalage AC; Lushington GH; Mehzabeen N; Battaile KP; Lovell S; Chang KO; Groutas WC
    Eur J Med Chem; 2017 Feb; 127():41-61. PubMed ID: 28038326
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-based exploration and exploitation of the S
    Galasiti Kankanamalage AC; Kim Y; Rathnayake AD; Damalanka VC; Weerawarna PM; Doyle ST; Alsoudi AF; Dissanayake DMP; Lushington GH; Mehzabeen N; Battaile KP; Lovell S; Chang KO; Groutas WC
    Eur J Med Chem; 2017 Jan; 126():502-516. PubMed ID: 27914364
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease.
    Damalanka VC; Kim Y; Galasiti Kankanamalage AC; Rathnayake AD; Mehzabeen N; Battaile KP; Lovell S; Nguyen HN; Lushington GH; Chang KO; Groutas WC
    Eur J Med Chem; 2018 Jan; 143():881-890. PubMed ID: 29227928
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studies.
    Galasiti Kankanamalage AC; Kim Y; Weerawarna PM; Uy RA; Damalanka VC; Mandadapu SR; Alliston KR; Mehzabeen N; Battaile KP; Lovell S; Chang KO; Groutas WC
    J Med Chem; 2015 Apr; 58(7):3144-55. PubMed ID: 25761614
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antiviral evaluation of novel peptidomimetics as norovirus protease inhibitors.
    Amblard F; Zhou S; Liu P; Yoon J; Cox B; Muzzarelli K; Kuiper BD; Kovari LC; Schinazi RF
    Bioorg Med Chem Lett; 2018 Jul; 28(12):2165-2170. PubMed ID: 29779977
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease.
    Damalanka VC; Kim Y; Alliston KR; Weerawarna PM; Galasiti Kankanamalage AC; Lushington GH; Mehzabeen N; Battaile KP; Lovell S; Chang KO; Groutas WC
    J Med Chem; 2016 Mar; 59(5):1899-913. PubMed ID: 26823007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease.
    Rathnayake AD; Kim Y; Dampalla CS; Nguyen HN; Jesri AM; Kashipathy MM; Lushington GH; Battaile KP; Lovell S; Chang KO; Groutas WC
    J Med Chem; 2020 Oct; 63(20):11945-11963. PubMed ID: 32945669
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery and Synthesis of Heterocyclic Carboxamide Derivatives as Potent Anti-norovirus Agents.
    Ohba M; Oka T; Ando T; Arahata S; Ikegaya A; Takagi H; Ogo N; Owada K; Kawamori F; Wang Q; Saif LJ; Asai A
    Chem Pharm Bull (Tokyo); 2016; 64(5):465-75. PubMed ID: 27150478
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of tripeptidyl alpha-ketoamides as human rhinovirus 3C protease inhibitors.
    Chen SH; Lamar J; Victor F; Snyder N; Johnson R; Heinz BA; Wakulchik M; Wang QM
    Bioorg Med Chem Lett; 2003 Oct; 13(20):3531-6. PubMed ID: 14505664
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A structural study of norovirus 3C protease specificity: binding of a designed active site-directed peptide inhibitor.
    Hussey RJ; Coates L; Gill RS; Erskine PT; Coker SF; Mitchell E; Cooper JB; Wood S; Broadbridge R; Clarke IN; Lambden PR; Shoolingin-Jordan PM
    Biochemistry; 2011 Jan; 50(2):240-9. PubMed ID: 21128685
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of inhibitors of noroviruses by scaffold hopping.
    Dou D; Mandadapu SR; Alliston KR; Kim Y; Chang KO; Groutas WC
    Bioorg Med Chem; 2011 Oct; 19(19):5749-55. PubMed ID: 21893416
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The enterovirus protease inhibitor rupintrivir exerts cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon.
    Rocha-Pereira J; Nascimento MS; Ma Q; Hilgenfeld R; Neyts J; Jochmans D
    Antimicrob Agents Chemother; 2014 Aug; 58(8):4675-81. PubMed ID: 24890597
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heteroaromatic ester inhibitors of hepatitis A virus 3C proteinase: Evaluation of mode of action.
    Huitema C; Zhang J; Yin J; James MN; Vederas JC; Eltis LD
    Bioorg Med Chem; 2008 May; 16(10):5761-77. PubMed ID: 18407505
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 1.
    Liu H; Tully DC; Epple R; Bursulaya B; Li J; Harris JL; Williams JA; Russo R; Tumanut C; Roberts MJ; Alper PB; He Y; Karanewsky DS
    Bioorg Med Chem Lett; 2005 Nov; 15(22):4979-84. PubMed ID: 16183279
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of amide and heteroaryl isosteres as carbamate replacements in a series of orally active gamma-secretase inhibitors.
    McBriar MD; Clader JW; Chu I; Del Vecchio RA; Favreau L; Greenlee WJ; Hyde LA; Nomeir AA; Parker EM; Pissarnitski DA; Song L; Zhang L; Zhao Z
    Bioorg Med Chem Lett; 2008 Jan; 18(1):215-9. PubMed ID: 17988864
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies.
    Weerawarna PM; Kim Y; Galasiti Kankanamalage AC; Damalanka VC; Lushington GH; Alliston KR; Mehzabeen N; Battaile KP; Lovell S; Chang KO; Groutas WC
    Eur J Med Chem; 2016 Aug; 119():300-18. PubMed ID: 27235842
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and inhibitor studies of norovirus 3C-like proteases.
    Takahashi D; Kim Y; Lovell S; Prakash O; Groutas WC; Chang KO
    Virus Res; 2013 Dec; 178(2):437-44. PubMed ID: 24055466
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.