265 related articles for article (PubMed ID: 22698814)
1. Ligand dependent hepatic gene expression profiles of nuclear receptors CAR and PXR.
Tojima H; Kakizaki S; Yamazaki Y; Takizawa D; Horiguchi N; Sato K; Mori M
Toxicol Lett; 2012 Aug; 212(3):288-97. PubMed ID: 22698814
[TBL] [Abstract][Full Text] [Related]
2. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
[TBL] [Abstract][Full Text] [Related]
3. Regulation of mouse organic anion-transporting polypeptides (Oatps) in liver by prototypical microsomal enzyme inducers that activate distinct transcription factor pathways.
Cheng X; Maher J; Dieter MZ; Klaassen CD
Drug Metab Dispos; 2005 Sep; 33(9):1276-82. PubMed ID: 15919853
[TBL] [Abstract][Full Text] [Related]
4. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response.
Beigneux AP; Moser AH; Shigenaga JK; Grunfeld C; Feingold KR
Biochem Biophys Res Commun; 2002 Apr; 293(1):145-9. PubMed ID: 12054576
[TBL] [Abstract][Full Text] [Related]
5. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; Viguié C; Martin PG
Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
[TBL] [Abstract][Full Text] [Related]
6. Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.
Slatter JG; Cheng O; Cornwell PD; de Souza A; Rockett J; Rushmore T; Hartley D; Evers R; He Y; Dai X; Hu R; Caguyong M; Roberts CJ; Castle J; Ulrich RG
Xenobiotica; 2006; 36(10-11):902-37. PubMed ID: 17118914
[TBL] [Abstract][Full Text] [Related]
7. Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
Anakk S; Huang W; Staudinger JL; Tan K; Cole TJ; Moore DD; Strobel HW
Drug Metab Dispos; 2007 Jan; 35(1):36-42. PubMed ID: 17020958
[TBL] [Abstract][Full Text] [Related]
8. Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1.
Braeuning A; Sanna R; Huelsken J; Schwarz M
Drug Metab Dispos; 2009 May; 37(5):1138-45. PubMed ID: 19237511
[TBL] [Abstract][Full Text] [Related]
9. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
Cui JY; Klaassen CD
Biochim Biophys Acta; 2016 Sep; 1859(9):1198-1217. PubMed ID: 27113289
[TBL] [Abstract][Full Text] [Related]
10. o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver.
Kiyosawa N; Kwekel JC; Burgoon LD; Williams KJ; Tashiro C; Chittim B; Zacharewski TR
Toxicol Sci; 2008 Feb; 101(2):350-63. PubMed ID: 17984292
[TBL] [Abstract][Full Text] [Related]
11. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
[TBL] [Abstract][Full Text] [Related]
12. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
Luisier R; Lempiäinen H; Scherbichler N; Braeuning A; Geissler M; Dubost V; Müller A; Scheer N; Chibout SD; Hara H; Picard F; Theil D; Couttet P; Vitobello A; Grenet O; Grasl-Kraupp B; Ellinger-Ziegelbauer H; Thomson JP; Meehan RR; Elcombe CR; Henderson CJ; Wolf CR; Schwarz M; Moulin P; Terranova R; Moggs JG
Toxicol Sci; 2014 Jun; 139(2):501-11. PubMed ID: 24690595
[TBL] [Abstract][Full Text] [Related]
13. Gene expression profiles of drug-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor.
Kakizaki S; Yamazaki Y; Kosone T; Horiguchi N; Sohara N; Sato K; Takagi H; Yoshinari K; Mori M
Liver Int; 2007 Feb; 27(1):109-19. PubMed ID: 17241389
[TBL] [Abstract][Full Text] [Related]
14. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
Xu DX; Wei W; Sun MF; Wu CY; Wang JP; Wei LZ; Zhou CF
Free Radic Biol Med; 2004 Jul; 37(1):10-22. PubMed ID: 15183191
[TBL] [Abstract][Full Text] [Related]
15. Hepatic cytochrome P450 gene regulation during endotoxin-induced inflammation in nuclear receptor knockout mice.
Richardson TA; Morgan ET
J Pharmacol Exp Ther; 2005 Aug; 314(2):703-9. PubMed ID: 15860574
[TBL] [Abstract][Full Text] [Related]
16. Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT.
Kiyosawa N; Kwekel JC; Burgoon LD; Dere E; Williams KJ; Tashiro C; Chittim B; Zacharewski TR
BMC Genomics; 2008 Oct; 9():487. PubMed ID: 18925944
[TBL] [Abstract][Full Text] [Related]
17. Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors.
Rouquié D; Tinwell H; Blanck O; Schorsch F; Geter D; Wason S; Bars R
Regul Toxicol Pharmacol; 2014 Dec; 70(3):673-80. PubMed ID: 25455223
[TBL] [Abstract][Full Text] [Related]
18. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.
Stedman CA; Liddle C; Coulter SA; Sonoda J; Alvarez JG; Moore DD; Evans RM; Downes M
Proc Natl Acad Sci U S A; 2005 Feb; 102(6):2063-8. PubMed ID: 15684063
[TBL] [Abstract][Full Text] [Related]
19. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
Kandel BA; Thomas M; Winter S; Damm G; Seehofer D; Burk O; Schwab M; Zanger UM
Biochim Biophys Acta; 2016 Sep; 1859(9):1218-1227. PubMed ID: 26994748
[TBL] [Abstract][Full Text] [Related]
20. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation.
Zhang H; LeCulyse E; Liu L; Hu M; Matoney L; Zhu W; Yan B
Arch Biochem Biophys; 1999 Aug; 368(1):14-22. PubMed ID: 10415106
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
