BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

262 related articles for article (PubMed ID: 22699360)

  • 1. Steric effects on the catalytic activities of zinc(II) complexes containing [12]aneN3 ligating units in the cleavage of the RNA and DNA model phosphates.
    Song Y; Zan J; Yan H; Lu ZL; Wang R
    Org Biomol Chem; 2012 Oct; 10(38):7714-20. PubMed ID: 22699360
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of mono- and di-[12]aneN3 ligands and study on the catalytic cleavage of RNA model 2-hydroxypropyl-p-nitrophenyl phosphate with their metal complexes.
    Guo ZF; Yan H; Li ZF; Lu ZL
    Org Biomol Chem; 2011 Oct; 9(19):6788-96. PubMed ID: 21887439
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cleavage of an RNA model catalyzed by dinuclear Zn(II) complexes containing rate-accelerating pendants. Comparison of the catalytic benefits of H-bonding and hydrophobic substituents.
    Mohamed MF; Brown RS
    J Org Chem; 2010 Dec; 75(24):8471-7. PubMed ID: 21087029
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigation of the effect of oxy bridging groups in dinuclear Zn(II) complexes that catalyze the cleavage of a simple phosphate diester RNA analogue.
    Mohamed MF; Neverov AA; Brown RS
    Inorg Chem; 2009 Dec; 48(23):11425-33. PubMed ID: 19874005
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cooperativity between metal ions in the cleavage of phosphate diesters and RNA by dinuclear Zn(II) catalysts.
    Iranzo O; Elmer T; Richard JP; Morrow JR
    Inorg Chem; 2003 Dec; 42(24):7737-46. PubMed ID: 14632489
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity studies on the cleavage of an RNA analogue by a potent dinuclear metal ion catalyst: effect of changing the metal ion.
    Iranzo O; Richard JP; Morrow JR
    Inorg Chem; 2004 Mar; 43(5):1743-50. PubMed ID: 14989667
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rapid three-step cleavage of RNA and DNA model systems promoted by a dinuclear Cu(II) complex in methanol. energetic origins of the catalytic efficacy.
    Lu ZL; Liu CT; Neverov AA; Brown RS
    J Am Chem Soc; 2007 Sep; 129(37):11642-52. PubMed ID: 17715924
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The dinuclear Zn(II) complex catalyzed cyclization of a series of 2-hydroxypropyl aryl phosphate RNA models: progressive change in mechanism from rate-limiting P-O bond cleavage to substrate binding.
    Bunn SE; Liu CT; Lu ZL; Neverov AA; Brown RS
    J Am Chem Soc; 2007 Dec; 129(51):16238-48. PubMed ID: 18047345
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Physical and kinetic analysis of the cooperative role of metal ions in catalysis of phosphodiester cleavage by a dinuclear Zn(II) complex.
    Iranzo O; Kovalevsky AY; Morrow JR; Richard JP
    J Am Chem Soc; 2003 Feb; 125(7):1988-93. PubMed ID: 12580627
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DFT computational study of the methanolytic cleavage of DNA and RNA phosphodiester models promoted by the dinuclear Zn(II) complex of 1,3-bis(1,5,9-triazacyclododec-1-yl)propane.
    Maxwell CI; Mosey NJ; Brown RS
    J Am Chem Soc; 2013 Nov; 135(45):17209-22. PubMed ID: 24111543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biomimetic cleavage of RNA models promoted by a dinuclear Zn(II) complex in ethanol. Greater than 30 kcal/mol stabilization of the transition state for cleavage of a phosphate diester.
    Liu CT; Neverov AA; Brown RS
    J Am Chem Soc; 2008 Dec; 130(49):16711-20. PubMed ID: 19554695
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cleavage of a RNA analog containing uridine by a bifunctional dinuclear Zn(II) catalyst.
    Rossiter CS; Mathews RA; del Mundo IM; Morrow JR
    J Inorg Biochem; 2009 Jan; 103(1):64-71. PubMed ID: 18952297
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Solvent induced cooperativity of Zn(II) complexes cleaving a phosphate diester RNA analog in methanol.
    Mohamed MF; Sánchez-Lombardo I; Neverov AA; Brown RS
    Org Biomol Chem; 2012 Jan; 10(3):631-9. PubMed ID: 22116167
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combination of a dinuclear Zn2+ complex and a medium effect exerts a 10(12)-fold rate enhancement of cleavage of an RNA and DNA model system.
    Neverov AA; Lu ZL; Maxwell CI; Mohamed MF; White CJ; Tsang JS; Brown RS
    J Am Chem Soc; 2006 Dec; 128(50):16398-405. PubMed ID: 17165797
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A simple DNase model system comprising a dinuclear Zn(II) complex in methanol accelerates the cleavage of a series of methyl aryl phosphate diesters by 10(11)-10(13).
    Neverov AA; Liu CT; Bunn SE; Edwards D; White CJ; Melnychuk SA; Brown RS
    J Am Chem Soc; 2008 May; 130(20):6639-49. PubMed ID: 18479083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and reactivity of a C3-symmetric trinuclear zinc(II) hydroxide catalyst efficient at phosphate diester transesterification.
    Mitra R; Peters MW; Scott MJ
    Dalton Trans; 2007 Sep; (35):3924-35. PubMed ID: 17893790
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Zn(II) coordination to polyamine macrocycles containing dipyridine units. New insights into the activity of dinuclear Zn(II) complexes in phosphate ester hydrolysis.
    Bazzicalupi C; Bencini A; Berni E; Bianchi A; Fornasari P; Giorgi C; Valtancoli B
    Inorg Chem; 2004 Oct; 43(20):6255-65. PubMed ID: 15446871
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Uridine binding by Zn(II) macrocyclic complexes: diversion of RNA cleavage catalysts.
    Rossiter CS; Mathews RA; Morrow JR
    Inorg Chem; 2005 Dec; 44(25):9397-404. PubMed ID: 16323926
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A reductionist biomimetic model system that demonstrates highly effective Zn(II)-catalyzed cleavage of an RNA model.
    Liu CT; Neverov AA; Brown RS
    Inorg Chem; 2007 Mar; 46(5):1778-88. PubMed ID: 17256929
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substrate specificity of an active dinuclear Zn(II) catalyst for cleavage of RNA analogues and a dinucleoside.
    O'Donoghue A; Pyun SY; Yang MY; Morrow JR; Richard JP
    J Am Chem Soc; 2006 Feb; 128(5):1615-21. PubMed ID: 16448134
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.