These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
6. Inhibition of DNA-repair genes Ercc1 and Mgmt enhances temozolomide efficacy in gliomas treatment: a pre-clinical study. Boccard SG; Marand SV; Geraci S; Pycroft L; Berger FR; Pelletier LA Oncotarget; 2015 Oct; 6(30):29456-68. PubMed ID: 26336131 [TBL] [Abstract][Full Text] [Related]
7. Combination of levetiracetam and IFN-α increased temozolomide efficacy in MGMT-positive glioma. Ni XR; Guo CC; Yu YJ; Yu ZH; Cai HP; Wu WC; Ma JX; Chen FR; Wang J; Chen ZP Cancer Chemother Pharmacol; 2020 Dec; 86(6):773-782. PubMed ID: 33074386 [TBL] [Abstract][Full Text] [Related]
8. Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression. Lan F; Yang Y; Han J; Wu Q; Yu H; Yue X Int J Oncol; 2016 Feb; 48(2):559-68. PubMed ID: 26648123 [TBL] [Abstract][Full Text] [Related]
9. Inhibition of NF-κB results in anti-glioma activity and reduces temozolomide-induced chemoresistance by down-regulating MGMT gene expression. Yu Z; Chen Y; Wang S; Li P; Zhou G; Yuan Y Cancer Lett; 2018 Aug; 428():77-89. PubMed ID: 29705182 [TBL] [Abstract][Full Text] [Related]
10. Interferon-α/β enhances temozolomide activity against MGMT-positive glioma stem-like cells. Shen D; Guo CC; Wang J; Qiu ZK; Sai K; Yang QY; Chen YS; Chen FR; Wang J; Panasci L; Chen ZP Oncol Rep; 2015 Nov; 34(5):2715-21. PubMed ID: 26329778 [TBL] [Abstract][Full Text] [Related]
11. AP-2α decreases TMZ resistance of recurrent GBM by downregulating MGMT expression and improving DNA damage. Huang G; Ouyang M; Xiao K; Zhou H; Zhong Z; Long S; Li Z; Zhang Y; Li L; Xiang S; Ding X Life Sci; 2024 Nov; 357():123111. PubMed ID: 39369843 [TBL] [Abstract][Full Text] [Related]
12. Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells. Happold C; Roth P; Wick W; Schmidt N; Florea AM; Silginer M; Reifenberger G; Weller M J Neurochem; 2012 Jul; 122(2):444-55. PubMed ID: 22564186 [TBL] [Abstract][Full Text] [Related]
13. Methionine restriction of glioma does not induce MGMT and greatly improves temozolomide efficacy in an orthotopic nude-mouse model: A potential curable approach to a clinically-incurable disease. Kubota Y; Aoki Y; Masaki N; Obara K; Hamada K; Han Q; Bouvet M; Tsunoda T; Hoffman RM Biochem Biophys Res Commun; 2024 Feb; 695():149418. PubMed ID: 38176171 [TBL] [Abstract][Full Text] [Related]
14. MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas. Oldrini B; Vaquero-Siguero N; Mu Q; Kroon P; Zhang Y; Galán-Ganga M; Bao Z; Wang Z; Liu H; Sa JK; Zhao J; Kim H; Rodriguez-Perales S; Nam DH; Verhaak RGW; Rabadan R; Jiang T; Wang J; Squatrito M Nat Commun; 2020 Aug; 11(1):3883. PubMed ID: 32753598 [TBL] [Abstract][Full Text] [Related]
15. Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation. Van Nifterik KA; Van den Berg J; Slotman BJ; Lafleur MV; Sminia P; Stalpers LJ J Neurooncol; 2012 Mar; 107(1):61-7. PubMed ID: 22037799 [TBL] [Abstract][Full Text] [Related]
16. Cedrol, a Sesquiterpene Alcohol, Enhances the Anticancer Efficacy of Temozolomide in Attenuating Drug Resistance via Regulation of the DNA Damage Response and MGMT Expression. Chang KF; Huang XF; Chang JT; Huang YC; Lo WS; Hsiao CY; Tsai NM J Nat Prod; 2020 Oct; 83(10):3021-3029. PubMed ID: 32960603 [TBL] [Abstract][Full Text] [Related]
17. Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model. Kitange GJ; Carlson BL; Mladek AC; Decker PA; Schroeder MA; Wu W; Grogan PT; Giannini C; Ballman KV; Buckner JC; James CD; Sarkaria JN J Neurooncol; 2009 Mar; 92(1):23-31. PubMed ID: 19011762 [TBL] [Abstract][Full Text] [Related]
18. Enhanced anti-tumor effect of zoledronic acid combined with temozolomide against human malignant glioma cell expressing O6-methylguanine DNA methyltransferase. Fukai J; Koizumi F; Nakao N PLoS One; 2014; 9(8):e104538. PubMed ID: 25111384 [TBL] [Abstract][Full Text] [Related]
19. O6-Methylguanine-methyltransferase (MGMT) promoter methylation status in glioma stem-like cells is correlated to temozolomide sensitivity under differentiation-promoting conditions. Villalva C; Cortes U; Wager M; Tourani JM; Rivet P; Marquant C; Martin S; Turhan AG; Karayan-Tapon L Int J Mol Sci; 2012; 13(6):6983-6994. PubMed ID: 22837675 [TBL] [Abstract][Full Text] [Related]
20. Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts. Kitange GJ; Carlson BL; Schroeder MA; Grogan PT; Lamont JD; Decker PA; Wu W; James CD; Sarkaria JN Neuro Oncol; 2009 Jun; 11(3):281-91. PubMed ID: 18952979 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]