190 related articles for article (PubMed ID: 22701533)
1. Withanolides-induced breast cancer cell death is correlated with their ability to inhibit heat protein 90.
Wang HC; Tsai YL; Wu YC; Chang FR; Liu MH; Chen WY; Wu CC
PLoS One; 2012; 7(5):e37764. PubMed ID: 22701533
[TBL] [Abstract][Full Text] [Related]
2. Tubocapsenolide A, a novel withanolide, inhibits proliferation and induces apoptosis in MDA-MB-231 cells by thiol oxidation of heat shock proteins.
Chen WY; Chang FR; Huang ZY; Chen JH; Wu YC; Wu CC
J Biol Chem; 2008 Jun; 283(25):17184-93. PubMed ID: 18442981
[TBL] [Abstract][Full Text] [Related]
3. Structure-activity relationship (SAR) of withanolides to inhibit Hsp90 for its activity in pancreatic cancer cells.
Gu M; Yu Y; Gunaherath GM; Gunatilaka AA; Li D; Sun D
Invest New Drugs; 2014 Feb; 32(1):68-74. PubMed ID: 23887853
[TBL] [Abstract][Full Text] [Related]
4. Different effects of 4β-hydroxywithanolide E and withaferin A, two withanolides from Solanaceae plants, on the Akt signaling pathway in human breast cancer cells.
Wang HC; Hu HH; Chang FR; Tsai JY; Kuo CY; Wu YC; Wu CC
Phytomedicine; 2019 Feb; 53():213-222. PubMed ID: 30668401
[TBL] [Abstract][Full Text] [Related]
5. Additive viability-loss following hsp70/hsc70 double interference and Hsp90 inhibition in two breast cancer cell lines.
Håvik B; Bramham CR
Oncol Rep; 2007 Jun; 17(6):1501-10. PubMed ID: 17487411
[TBL] [Abstract][Full Text] [Related]
6. Anti-cancer activity of withaferin A in B-cell lymphoma.
McKenna MK; Gachuki BW; Alhakeem SS; Oben KN; Rangnekar VM; Gupta RC; Bondada S
Cancer Biol Ther; 2015; 16(7):1088-98. PubMed ID: 26020511
[TBL] [Abstract][Full Text] [Related]
7. The flavonoid TL-2-8 induces cell death and immature mitophagy in breast cancer cells via abrogating the function of the AHA1/Hsp90 complex.
Liu HJ; Jiang XX; Guo YZ; Sun FH; Kou XH; Bao Y; Zhang ZQ; Lin ZH; Ding TB; Jiang L; Lei XS; Yang YH
Acta Pharmacol Sin; 2017 Oct; 38(10):1381-1393. PubMed ID: 28504248
[TBL] [Abstract][Full Text] [Related]
8. Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.
Broemer M; Krappmann D; Scheidereit C
Oncogene; 2004 Jul; 23(31):5378-86. PubMed ID: 15077173
[TBL] [Abstract][Full Text] [Related]
9. Blocking NF-κB and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death.
Bai L; Xu S; Chen W; Li Z; Wang X; Tang H; Lin Y
Apoptosis; 2011 Jan; 16(1):45-54. PubMed ID: 20862547
[TBL] [Abstract][Full Text] [Related]
10. Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90.
Salminen A; Paimela T; Suuronen T; Kaarniranta K
Immunol Lett; 2008 Apr; 117(1):9-15. PubMed ID: 18282612
[TBL] [Abstract][Full Text] [Related]
11. Hsp90/Cdc37 chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A.
Grover A; Shandilya A; Agrawal V; Pratik P; Bhasme D; Bisaria VS; Sundar D
BMC Bioinformatics; 2011 Feb; 12 Suppl 1(Suppl 1):S30. PubMed ID: 21342561
[TBL] [Abstract][Full Text] [Related]
12. Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer.
Srirangam A; Mitra R; Wang M; Gorski JC; Badve S; Baldridge L; Hamilton J; Kishimoto H; Hawes J; Li L; Orschell CM; Srour EF; Blum JS; Donner D; Sledge GW; Nakshatri H; Potter DA
Clin Cancer Res; 2006 Mar; 12(6):1883-96. PubMed ID: 16551874
[TBL] [Abstract][Full Text] [Related]
13. NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models.
Jensen MR; Schoepfer J; Radimerski T; Massey A; Guy CT; Brueggen J; Quadt C; Buckler A; Cozens R; Drysdale MJ; Garcia-Echeverria C; Chène P
Breast Cancer Res; 2008; 10(2):R33. PubMed ID: 18430202
[TBL] [Abstract][Full Text] [Related]
14. Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells.
Gougelet A; Bouclier C; Marsaud V; Maillard S; Mueller SO; Korach KS; Renoir JM
J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):71-81. PubMed ID: 15862952
[TBL] [Abstract][Full Text] [Related]
15. Withaferin A targets heat shock protein 90 in pancreatic cancer cells.
Yu Y; Hamza A; Zhang T; Gu M; Zou P; Newman B; Li Y; Gunatilaka AA; Zhan CG; Sun D
Biochem Pharmacol; 2010 Feb; 79(4):542-51. PubMed ID: 19769945
[TBL] [Abstract][Full Text] [Related]
16. A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
Massey AJ; Williamson DS; Browne H; Murray JB; Dokurno P; Shaw T; Macias AT; Daniels Z; Geoffroy S; Dopson M; Lavan P; Matassova N; Francis GL; Graham CJ; Parsons R; Wang Y; Padfield A; Comer M; Drysdale MJ; Wood M
Cancer Chemother Pharmacol; 2010 Aug; 66(3):535-45. PubMed ID: 20012863
[TBL] [Abstract][Full Text] [Related]
17. Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
El-Shafey HW; Gomaa RM; El-Messery SM; Goda FE
Bioorg Med Chem Lett; 2020 Aug; 30(15):127281. PubMed ID: 32527460
[TBL] [Abstract][Full Text] [Related]
18. Obligatory role of heat shock protein 90 in iNOS induction.
Luo S; Wang T; Qin H; Lei H; Xia Y
Am J Physiol Cell Physiol; 2011 Jul; 301(1):C227-33. PubMed ID: 21430289
[TBL] [Abstract][Full Text] [Related]
19. Epigallocatechin-3-gallate suppresses the expression of HSP70 and HSP90 and exhibits anti-tumor activity in vitro and in vivo.
Tran PL; Kim SA; Choi HS; Yoon JH; Ahn SG
BMC Cancer; 2010 Jun; 10():276. PubMed ID: 20537126
[TBL] [Abstract][Full Text] [Related]
20. Disruption of hsp90 function results in degradation of the death domain kinase, receptor-interacting protein (RIP), and blockage of tumor necrosis factor-induced nuclear factor-kappaB activation.
Lewis J; Devin A; Miller A; Lin Y; Rodriguez Y; Neckers L; Liu ZG
J Biol Chem; 2000 Apr; 275(14):10519-26. PubMed ID: 10744744
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
