153 related articles for article (PubMed ID: 22709003)
1. Synthetic 2-methoxyestradiol derivatives: structure-activity relationships.
Peyrat JF; Brion JD; Alami M
Curr Med Chem; 2012; 19(24):4142-56. PubMed ID: 22709003
[TBL] [Abstract][Full Text] [Related]
2. Mechanism of action of 2-methoxyestradiol: new developments.
Mooberry SL
Drug Resist Updat; 2003 Dec; 6(6):355-61. PubMed ID: 14744499
[TBL] [Abstract][Full Text] [Related]
3. Recent Advances in chemistry and pharmacology of 2-methoxyestradiol: An anticancer investigational drug.
Kumar BS; Raghuvanshi DS; Hasanain M; Alam S; Sarkar J; Mitra K; Khan F; Negi AS
Steroids; 2016 Jun; 110():9-34. PubMed ID: 27020471
[TBL] [Abstract][Full Text] [Related]
4. Role of 2-methoxyestradiol, an Endogenous Estrogen Metabolite, in Health and Disease.
Parada-Bustamante A; Valencia C; Reuquen P; Diaz P; Rincion-Rodriguez R; Orihuela PA
Mini Rev Med Chem; 2015; 15(5):427-38. PubMed ID: 25723461
[TBL] [Abstract][Full Text] [Related]
5. The effect of exchanging various substituents at the 2-position of 2-methoxyestradiol on cytotoxicity in human cancer cell cultures and inhibition of tubulin polymerization.
Cushman M; Mohanakrishnan AK; Hollingshead M; Hamel E
J Med Chem; 2002 Oct; 45(21):4748-54. PubMed ID: 12361402
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and antimitotic activity of novel 2-methoxyestradiol analogs.
Rao PN; Cessac JW; Tinley TL; Mooberry SL
Steroids; 2002 Dec; 67(13-14):1079-89. PubMed ID: 12441194
[TBL] [Abstract][Full Text] [Related]
7. Structure activity analysis of 2-methoxyestradiol analogues reveals targeting of microtubules as the major mechanism of antiproliferative and proapoptotic activity.
Chua YS; Chua YL; Hagen T
Mol Cancer Ther; 2010 Jan; 9(1):224-35. PubMed ID: 20053769
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and Pharmacological Effects of the Anti-Cancer Agent 2-Methoxyestradiol.
Solum EJ; Akselsen ØW; Vik A; Hansen TV
Curr Pharm Des; 2015; 21(38):5453-66. PubMed ID: 26429718
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and structure-activity relationships of 16-modified analogs of 2-methoxyestradiol.
Agoston GE; Shah JH; Lavallee TM; Zhan X; Pribluda VS; Treston AM
Bioorg Med Chem; 2007 Dec; 15(24):7524-37. PubMed ID: 17910916
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and antimitotic activity of novel 2-methoxyestradiol analogs. Part III.
Rao PN; Cessac JW; Boyd JW; Hanson AD; Shah J
Steroids; 2008 Feb; 73(2):171-83. PubMed ID: 18155739
[TBL] [Abstract][Full Text] [Related]
11. New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent.
Mooberry SL
Curr Opin Oncol; 2003 Nov; 15(6):425-30. PubMed ID: 14624224
[TBL] [Abstract][Full Text] [Related]
12. Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.
Visagie M; Theron A; Mqoco T; Vieira W; Prudent R; Martinez A; Lafanechère L; Joubert A
PLoS One; 2013; 8(9):e71935. PubMed ID: 24039728
[TBL] [Abstract][Full Text] [Related]
13. The physiological estrogen metabolite 2-methoxyestradiol reduces tumor growth and induces apoptosis in human solid tumors.
Schumacher G; Neuhaus P
J Cancer Res Clin Oncol; 2001 Jul; 127(7):405-10. PubMed ID: 11469676
[TBL] [Abstract][Full Text] [Related]
14. A short, economical synthesis of 2-methoxyestradiol, an anticancer agent in clinical trials.
Hou Y; Meyers CY; Akomeah M
J Org Chem; 2009 Aug; 74(16):6362-4. PubMed ID: 19610601
[TBL] [Abstract][Full Text] [Related]
15. 2-Methoxyestradiol and analogs as novel antiproliferative agents: analysis of three-dimensional quantitative structure-activity relationships for DNA synthesis inhibition and estrogen receptor binding.
Hughes RA; Harris T; Altmann E; McAllister D; Vlahos R; Robertson A; Cushman M; Wang Z; Stewart AG
Mol Pharmacol; 2002 May; 61(5):1053-69. PubMed ID: 11961123
[TBL] [Abstract][Full Text] [Related]
16. 2-Methoxyestradiol, a promising anticancer agent.
Lakhani NJ; Sarkar MA; Venitz J; Figg WD
Pharmacotherapy; 2003 Feb; 23(2):165-72. PubMed ID: 12587805
[TBL] [Abstract][Full Text] [Related]
17. Therapeutic promises of 2-methoxyestradiol and its drug disposition challenges.
Verenich S; Gerk PM
Mol Pharm; 2010 Dec; 7(6):2030-9. PubMed ID: 20831190
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
Wang Z; Yang D; Mohanakrishnan AK; Fanwick PE; Nampoothiri P; Hamel E; Cushman M
J Med Chem; 2000 Jun; 43(12):2419-29. PubMed ID: 10882369
[TBL] [Abstract][Full Text] [Related]
19. Neuronal nitric oxide synthase induction in the antitumorigenic and neurotoxic effects of 2-methoxyestradiol.
Gorska M; Kuban-Jankowska A; Zmijewski MA; Gorzynik M; Szkatula M; Wozniak M
Molecules; 2014 Aug; 19(9):13267-81. PubMed ID: 25170949
[TBL] [Abstract][Full Text] [Related]
20. Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors.
Dahut WL; Lakhani NJ; Gulley JL; Arlen PM; Kohn EC; Kotz H; McNally D; Parr A; Nguyen D; Yang SX; Steinberg SM; Venitz J; Sparreboom A; Figg WD
Cancer Biol Ther; 2006 Jan; 5(1):22-7. PubMed ID: 16357512
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]