170 related articles for article (PubMed ID: 22710402)
1. Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.
Schaap MM; Zwart EP; Wackers PF; Huijskens I; van de Water B; Breit TM; van Steeg H; Jonker MJ; Luijten M
Arch Toxicol; 2012 Nov; 86(11):1717-27. PubMed ID: 22710402
[TBL] [Abstract][Full Text] [Related]
2. A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.
Schaap MM; Wackers PF; Zwart EP; Huijskens I; Jonker MJ; Hendriks G; Breit TM; van Steeg H; van de Water B; Luijten M
Arch Toxicol; 2015 Dec; 89(12):2413-27. PubMed ID: 25270620
[TBL] [Abstract][Full Text] [Related]
3. Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time.
Mathijs K; Brauers KJ; Jennen DG; Boorsma A; van Herwijnen MH; Gottschalk RW; Kleinjans JC; van Delft JH
Toxicol Sci; 2009 Dec; 112(2):374-84. PubMed ID: 19770486
[TBL] [Abstract][Full Text] [Related]
4. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
Doktorova TY; Ellinger-Ziegelbauer H; Vinken M; Vanhaecke T; van Delft J; Kleinjans J; Ahr HJ; Rogiers V
Arch Toxicol; 2012 Sep; 86(9):1399-411. PubMed ID: 22484513
[TBL] [Abstract][Full Text] [Related]
5. Gene expression profiling in primary mouse hepatocytes discriminates true from false-positive genotoxic compounds.
Mathijs K; Brauers KJ; Jennen DG; Lizarraga D; Kleinjans JC; van Delft JH
Mutagenesis; 2010 Nov; 25(6):561-8. PubMed ID: 20650930
[TBL] [Abstract][Full Text] [Related]
6. In vivo Comet assay on isolated kidney cells to distinguish genotoxic carcinogens from epigenetic carcinogens or cytotoxic compounds.
Nesslany F; Zennouche N; Simar-Meintières S; Talahari I; Nkili-Mboui EN; Marzin D
Mutat Res; 2007 Jun; 630(1-2):28-41. PubMed ID: 17507283
[TBL] [Abstract][Full Text] [Related]
7. Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling.
van Delft JH; van Agen E; van Breda SG; Herwijnen MH; Staal YC; Kleinjans JC
Mutat Res; 2005 Aug; 575(1-2):17-33. PubMed ID: 15924884
[TBL] [Abstract][Full Text] [Related]
8. Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: toxicokinetics is essential for in vivo-in vitro comparisons.
van Kesteren PC; Zwart PE; Schaap MM; Pronk TE; van Herwijnen MH; Kleinjans JC; Bokkers BG; Godschalk RW; Zeilmaker MJ; van Steeg H; Luijten M
Arch Toxicol; 2013 Mar; 87(3):505-15. PubMed ID: 23052197
[TBL] [Abstract][Full Text] [Related]
9. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
Doktorova TY; Yildirimman R; Vinken M; Vilardell M; Vanhaecke T; Gmuender H; Bort R; Brolen G; Holmgren G; Li R; Chesne C; van Delft J; Kleinjans J; Castell J; Bjorquist P; Herwig R; Rogiers V
Carcinogenesis; 2013 Jun; 34(6):1393-402. PubMed ID: 23393228
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity.
Kirkland D; Aardema M; Henderson L; Müller L
Mutat Res; 2005 Jul; 584(1-2):1-256. PubMed ID: 15979392
[TBL] [Abstract][Full Text] [Related]
11. Are tumor incidence rates from chronic bioassays telling us what we need to know about carcinogens?
Gaylor DW
Regul Toxicol Pharmacol; 2005 Mar; 41(2):128-33. PubMed ID: 15698536
[TBL] [Abstract][Full Text] [Related]
12. Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.
Josse R; Dumont J; Fautrel A; Robin MA; Guillouzo A
Toxicol Appl Pharmacol; 2012 Jan; 258(2):176-87. PubMed ID: 22100608
[TBL] [Abstract][Full Text] [Related]
13. Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.
van Kesteren PC; Zwart PE; Pennings JL; Gottschalk WH; Kleinjans JC; van Delft JH; van Steeg H; Luijten M
Toxicol Sci; 2011 Sep; 123(1):123-32. PubMed ID: 21715664
[TBL] [Abstract][Full Text] [Related]
14. Further analysis of Ames-negative rodent carcinogens that are only genotoxic in mammalian cells in vitro at concentrations exceeding 1 mM, including retesting of compounds of concern.
Kirkland D; Fowler P
Mutagenesis; 2010 Nov; 25(6):539-53. PubMed ID: 20720197
[TBL] [Abstract][Full Text] [Related]
15. Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment.
Hendriks G; Atallah M; Raamsman M; Morolli B; van der Putten H; Jaadar H; Tijdens I; Esveldt-van Lange R; Mullenders L; van de Water B; Vrieling H
Mutat Res; 2011 May; 709-710():49-59. PubMed ID: 21382384
[TBL] [Abstract][Full Text] [Related]
16. Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.
Jonker MJ; Bruning O; van Iterson M; Schaap MM; van der Hoeven TV; Vrieling H; Beems RB; de Vries A; van Steeg H; Breit TM; Luijten M
Carcinogenesis; 2009 Oct; 30(10):1805-12. PubMed ID: 19696161
[TBL] [Abstract][Full Text] [Related]
17. Identification of potential biomarkers of genotoxicity and carcinogenicity in L5178Y mouse lymphoma cells by cDNA microarray analysis.
Kim JY; Kwon J; Kim JE; Koh WS; Chung MK; Yoon S; Song CW; Lee M
Environ Mol Mutagen; 2005; 45(1):80-9. PubMed ID: 15612046
[TBL] [Abstract][Full Text] [Related]
18. Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity.
Rieswijk L; Brauers KJ; Coonen ML; Jennen DG; van Breda SG; Kleinjans JC
Mutagenesis; 2016 Sep; 31(5):603-15. PubMed ID: 27338304
[TBL] [Abstract][Full Text] [Related]
19. Failure of the standard battery of short-term tests in detecting some rodent and human genotoxic carcinogens.
Brambilla G; Martelli A
Toxicology; 2004 Mar; 196(1-2):1-19. PubMed ID: 15036752
[TBL] [Abstract][Full Text] [Related]
20. Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver.
Ellinger-Ziegelbauer H; Stuart B; Wahle B; Bomann W; Ahr HJ
Mutat Res; 2005 Aug; 575(1-2):61-84. PubMed ID: 15890375
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]