BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 22713343)

  • 1. DNA binding residues in the RQC domain of Werner protein are critical for its catalytic activities.
    Tadokoro T; Kulikowicz T; Dawut L; Croteau DL; Bohr VA
    Aging (Albany NY); 2012 Jun; 4(6):417-29. PubMed ID: 22713343
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intrinsic ssDNA annealing activity in the C-terminal region of WRN.
    Muftuoglu M; Kulikowicz T; Beck G; Lee JW; Piotrowski J; Bohr VA
    Biochemistry; 2008 Sep; 47(39):10247-54. PubMed ID: 18771289
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain.
    Lee JW; Kusumoto R; Doherty KM; Lin GX; Zeng W; Cheng WH; von Kobbe C; Brosh RM; Hu JS; Bohr VA
    J Biol Chem; 2005 Nov; 280(47):39627-36. PubMed ID: 16150736
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional deficit associated with a missense Werner syndrome mutation.
    Tadokoro T; Rybanska-Spaeder I; Kulikowicz T; Dawut L; Oshima J; Croteau DL; Bohr VA
    DNA Repair (Amst); 2013 Jun; 12(6):414-21. PubMed ID: 23583337
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN.
    Kitano K; Kim SY; Hakoshima T
    Structure; 2010 Feb; 18(2):177-87. PubMed ID: 20159463
    [TBL] [Abstract][Full Text] [Related]  

  • 6. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
    Aggarwal M; Brosh RM
    Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
    Machwe A; Lozada EM; Xiao L; Orren DK
    BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing.
    Kusumoto R; Dawut L; Marchetti C; Wan Lee J; Vindigni A; Ramsden D; Bohr VA
    Biochemistry; 2008 Jul; 47(28):7548-56. PubMed ID: 18558713
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of the HRDC domain of human Werner syndrome protein, WRN.
    Kitano K; Yoshihara N; Hakoshima T
    J Biol Chem; 2007 Jan; 282(4):2717-28. PubMed ID: 17148451
    [TBL] [Abstract][Full Text] [Related]  

  • 10. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
    Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
    Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops.
    Kusumoto-Matsuo R; Opresko PL; Ramsden D; Tahara H; Bohr VA
    Aging (Albany NY); 2010 May; 2(5):274-84. PubMed ID: 20519774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Werner syndrome protein binds replication fork and holliday junction DNAs as an oligomer.
    Compton SA; Tolun G; Kamath-Loeb AS; Loeb LA; Griffith JD
    J Biol Chem; 2008 Sep; 283(36):24478-83. PubMed ID: 18596042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.
    Opresko PL; Laine JP; Brosh RM; Seidman MM; Bohr VA
    J Biol Chem; 2001 Nov; 276(48):44677-87. PubMed ID: 11572872
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.
    Shen JC; Gray MD; Oshima J; Kamath-Loeb AS; Fry M; Loeb LA
    J Biol Chem; 1998 Dec; 273(51):34139-44. PubMed ID: 9852073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase Are Involved in Unwinding G-quadruplex DNA.
    Ketkar A; Voehler M; Mukiza T; Eoff RL
    J Biol Chem; 2017 Feb; 292(8):3154-3163. PubMed ID: 28069813
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation.
    Opresko PL; Sowd G; Wang H
    PLoS One; 2009; 4(3):e4825. PubMed ID: 19283071
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions.
    Popp O; Veith S; Fahrer J; Bohr VA; Bürkle A; Mangerich A
    ACS Chem Biol; 2013 Jan; 8(1):179-88. PubMed ID: 23082994
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Replication protein A stimulates the Werner syndrome protein branch migration activity.
    Sowd G; Wang H; Pretto D; Chazin WJ; Opresko PL
    J Biol Chem; 2009 Dec; 284(50):34682-91. PubMed ID: 19812417
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Drosophila orthologue of progeroid human WRN exonuclease, DmWRNexo, cleaves replication substrates but is inhibited by uracil or abasic sites : analysis of DmWRNexo activity in vitro.
    Mason PA; Boubriak I; Robbins T; Lasala R; Saunders R; Cox LS
    Age (Dordr); 2013 Jun; 35(3):793-806. PubMed ID: 22562358
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation.
    Karmakar P; Piotrowski J; Brosh RM; Sommers JA; Miller SP; Cheng WH; Snowden CM; Ramsden DA; Bohr VA
    J Biol Chem; 2002 May; 277(21):18291-302. PubMed ID: 11889123
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.