120 related articles for article (PubMed ID: 2271521)
1. Inhibition of chymotrypsin by peptidyl trifluoromethyl ketones: determinants of slow-binding kinetics.
Brady K; Abeles RH
Biochemistry; 1990 Aug; 29(33):7608-17. PubMed ID: 2271521
[TBL] [Abstract][Full Text] [Related]
2. Correlations of the basicity of His 57 with transition state analogue binding, substrate reactivity, and the strength of the low-barrier hydrogen bond in chymotrypsin.
Lin J; Cassidy CS; Frey PA
Biochemistry; 1998 Aug; 37(34):11940-8. PubMed ID: 9718318
[TBL] [Abstract][Full Text] [Related]
3. Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors.
Brady K; Wei AZ; Ringe D; Abeles RH
Biochemistry; 1990 Aug; 29(33):7600-7. PubMed ID: 2271520
[TBL] [Abstract][Full Text] [Related]
4. pH dependence of the inhibition of chymotrypsin by a peptidyl trifluoromethyl ketone.
Brady K; Liang TC; Abeles RH
Biochemistry; 1989 Nov; 28(23):9066-70. PubMed ID: 2605240
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of serine proteases by peptidyl fluoromethyl ketones.
Imperiali B; Abeles RH
Biochemistry; 1986 Jul; 25(13):3760-7. PubMed ID: 3527255
[TBL] [Abstract][Full Text] [Related]
6. Fractionation factors and activation energies for exchange of the low barrier hydrogen bonding proton in peptidyl trifluoromethyl ketone complexes of chymotrypsin.
Lin J; Westler WM; Cleland WW; Markley JL; Frey PA
Proc Natl Acad Sci U S A; 1998 Dec; 95(25):14664-8. PubMed ID: 9843946
[TBL] [Abstract][Full Text] [Related]
7. A new concept for the mechanism of action of chymotrypsin: the role of the low-barrier hydrogen bond.
Cassidy CS; Lin J; Frey PA
Biochemistry; 1997 Apr; 36(15):4576-84. PubMed ID: 9109667
[TBL] [Abstract][Full Text] [Related]
8. Designing of substrates and inhibitors of bovine alpha-chymotrypsin with synthetic phenylalanine analogues in position P(1).
Wysocka M; Lesner A; Legowska A; Jaśkiewicz A; Miecznikowska H; Rolka K
Protein Pept Lett; 2008; 15(3):260-4. PubMed ID: 18336354
[TBL] [Abstract][Full Text] [Related]
9. Enzyme-inhibitory conformation of dipeptides containing sterically constrained amino acid 2,3-methanophenylalanine.
Ogawa T; Kodama H; Yoshioka K; Shimohigashi Y
Pept Res; 1990; 3(1):35-41. PubMed ID: 2134046
[TBL] [Abstract][Full Text] [Related]
10. N-[2,2-dimethyl-3-(N-(4-cyanobenzoyl)amino)nonanoyl]-L-phenylalanine ethyl ester as a stable ester-type inhibitor of chymotrypsin-like serine proteases: structural requirements for potent inhibition of alpha-chymotrypsin.
Iijima K; Katada J; Yasuda E; Uno I; Hayashi Y
J Med Chem; 1999 Jan; 42(2):312-23. PubMed ID: 9925737
[TBL] [Abstract][Full Text] [Related]
11. Molecular recognition in acetylcholinesterase catalysis: free-energy correlations for substrate turnover and inhibition by trifluoro ketone transition-state analogs.
Nair HK; Seravalli J; Arbuckle T; Quinn DM
Biochemistry; 1994 Jul; 33(28):8566-76. PubMed ID: 8031791
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of cathepsin B by peptidyl aldehydes and ketones: slow-binding behavior of a trifluoromethyl ketone.
Smith RA; Copp LJ; Donnelly SL; Spencer RW; Krantz A
Biochemistry; 1988 Aug; 27(17):6568-73. PubMed ID: 3219354
[TBL] [Abstract][Full Text] [Related]
13. Chymotrypsin inhibitory conformation of dipeptides constructed by side chain-side chain hydrophobic interactions.
Sakamoto H; Shimohigashi Y; Maeda I; Nose T; Nakashima K; Nakamura I; Ogawa T; Kawano K; Ohno M
J Mol Recognit; 1993 Jun; 6(2):95-100. PubMed ID: 8305253
[TBL] [Abstract][Full Text] [Related]
14. Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors.
Powers JC; Tanaka T; Harper JW; Minematsu Y; Barker L; Lincoln D; Crumley KV; Fraki JE; Schechter NM; Lazarus GG
Biochemistry; 1985 Apr; 24(8):2048-58. PubMed ID: 3893542
[TBL] [Abstract][Full Text] [Related]
15. Specific inhibitory conformation of dipeptides for chymotrypsin.
Shimohigashi Y; Ogawa T; Kodama H; Sakamoto H; Yoshitomi H; Waki M; Ohno M
Biochem Biophys Res Commun; 1990 Feb; 166(3):1460-6. PubMed ID: 2306257
[TBL] [Abstract][Full Text] [Related]
16. Enzyme inhibition by dipeptides containing 2,3-methanophenylalanine, a sterically constrained amino acid.
Ogawa T; Yoshitomi H; Kodama H; Waki M; Stammer CH; Shimohigashi Y
FEBS Lett; 1989 Jul; 250(2):227-30. PubMed ID: 2753131
[TBL] [Abstract][Full Text] [Related]
17. Complex of alpha-chymotrypsin and N-acetyl-L-leucyl-L-phenylalanyl trifluoromethyl ketone: structural studies with NMR spectroscopy.
Liang TC; Abeles RH
Biochemistry; 1987 Dec; 26(24):7603-8. PubMed ID: 3427096
[TBL] [Abstract][Full Text] [Related]
18. Peptidyl human heart chymase inhibitors. 1. Synthesis and inhibitory activity of difluoromethylene ketone derivatives bearing P' binding subsites.
Eda M; Ashimori A; Akahoshi F; Yoshimura T; Inoue Y; Fukaya C; Nakajima M; Fukuyama H; Imada T; Takai S; Shiota N; Miyazaki M; Nakamura N
Bioorg Med Chem Lett; 1998 Apr; 8(8):913-8. PubMed ID: 9871511
[TBL] [Abstract][Full Text] [Related]
19. Chymotrypsin inhibition induced by side chain-side chain intramolecular CH/pi interaction in D-Thr-L-Phe benzylamide.
Maeda I; Shimohigashi Y; Ikesue K; Nose T; Ide Y; Kawano K; Ohno M
J Biochem; 1996 May; 119(5):870-7. PubMed ID: 8797086
[TBL] [Abstract][Full Text] [Related]
20. Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones.
Kreutter K; Steinmetz AC; Liang TC; Prorok M; Abeles RH; Ringe D
Biochemistry; 1994 Nov; 33(46):13792-800. PubMed ID: 7947790
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
