BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 22719950)

  • 1. Regulation of RasGRP1 function in T cell development and activation by its unique tail domain.
    Fuller DM; Zhu M; Song X; Ou-Yang CW; Sullivan SA; Stone JC; Zhang W
    PLoS One; 2012; 7(6):e38796. PubMed ID: 22719950
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.
    Golec DP; Dower NA; Stone JC; Baldwin TA
    PLoS One; 2013; 8(1):e53300. PubMed ID: 23308188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development.
    Priatel JJ; Chen X; Dhanji S; Abraham N; Teh HS
    J Immunol; 2006 Aug; 177(3):1470-80. PubMed ID: 16849453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.
    Roose JP; Mollenauer M; Gupta VA; Stone J; Weiss A
    Mol Cell Biol; 2005 Jun; 25(11):4426-41. PubMed ID: 15899849
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preferential development of CD4 and CD8 T regulatory cells in RasGRP1-deficient mice.
    Chen X; Priatel JJ; Chow MT; Teh HS
    J Immunol; 2008 May; 180(9):5973-82. PubMed ID: 18424717
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chronic immunodeficiency in mice lacking RasGRP1 results in CD4 T cell immune activation and exhaustion.
    Priatel JJ; Chen X; Zenewicz LA; Shen H; Harder KW; Horwitz MS; Teh HS
    J Immunol; 2007 Aug; 179(4):2143-52. PubMed ID: 17675473
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RasGRP1 and RasGRP3 Are Required for Efficient Generation of Early Thymic Progenitors.
    Golec DP; Henao Caviedes LM; Baldwin TA
    J Immunol; 2016 Sep; 197(5):1743-53. PubMed ID: 27465532
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells.
    Schneider H; Wang H; Raab M; Valk E; Smith X; Lovatt M; Wu Z; Maqueira-Iglesias B; Strebhardt K; Rudd CE
    PLoS One; 2008 Mar; 3(3):e1718. PubMed ID: 18320039
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential requirement of RasGRP1 for γδ T cell development and activation.
    Chen Y; Ci X; Gorentla B; Sullivan SA; Stone JC; Zhang W; Pereira P; Lu J; Zhong XP
    J Immunol; 2012 Jul; 189(1):61-71. PubMed ID: 22623331
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthetic bryostatin analogues activate the RasGRP1 signaling pathway.
    Stone JC; Stang SL; Zheng Y; Dower NA; Brenner SE; Baryza JL; Wender PA
    J Med Chem; 2004 Dec; 47(26):6638-44. PubMed ID: 15588099
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G alpha i2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions.
    Kremer KN; Kumar A; Hedin KE
    J Immunol; 2011 Sep; 187(6):3177-85. PubMed ID: 21856938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cutting Edge: Induced Loss of Rasgrp1 in Peripheral CD4+ T Cells of Conditional Rasgrp1-Deficient Mice Reveals an Essential Role for Rasgrp1 in TCR/CD28-Induced Ras-MAPK Signaling.
    Chang Y; Manivannan P; Doosti A; Lapinski PE; Chen D; Roose JP; King PD
    J Immunol; 2023 Sep; 211(6):917-922. PubMed ID: 37566514
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sos1 regulates sustained TCR-mediated Erk activation.
    Poltorak M; Meinert I; Stone JC; Schraven B; Simeoni L
    Eur J Immunol; 2014 May; 44(5):1535-40. PubMed ID: 24497027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.
    Daley SR; Coakley KM; Hu DY; Randall KL; Jenne CN; Limnander A; Myers DR; Polakos NK; Enders A; Roots C; Balakishnan B; Miosge LA; Sjollema G; Bertram EM; Field MA; Shao Y; Andrews TD; Whittle B; Barnes SW; Walker JR; Cyster JG; Goodnow CC; Roose JP
    Elife; 2013 Dec; 2():e01020. PubMed ID: 24336796
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.
    Priatel JJ; Teh SJ; Dower NA; Stone JC; Teh HS
    Immunity; 2002 Nov; 17(5):617-27. PubMed ID: 12433368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RasGRP1 regulates antigen-induced developmental programming by naive CD8 T cells.
    Priatel JJ; Chen X; Huang YH; Chow MT; Zenewicz LA; Coughlin JJ; Shen H; Stone JC; Tan R; Teh HS
    J Immunol; 2010 Jan; 184(2):666-76. PubMed ID: 20007535
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deconstructing Ras signaling in the thymus.
    Kortum RL; Sommers CL; Pinski JM; Alexander CP; Merrill RK; Li W; Love PE; Samelson LE
    Mol Cell Biol; 2012 Jul; 32(14):2748-59. PubMed ID: 22586275
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A phospholipase C-γ1-independent, RasGRP1-ERK-dependent pathway drives lymphoproliferative disease in linker for activation of T cells-Y136F mutant mice.
    Kortum RL; Rouquette-Jazdanian AK; Miyaji M; Merrill RK; Markegard E; Pinski JM; Wesselink A; Nath NN; Alexander CP; Li W; Kedei N; Roose JP; Blumberg PM; Samelson LE; Sommers CL
    J Immunol; 2013 Jan; 190(1):147-58. PubMed ID: 23209318
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thymic progenitors of TCRαβ
    Golec DP; Hoeppli RE; Henao Caviedes LM; McCann J; Levings MK; Baldwin TA
    J Exp Med; 2017 Aug; 214(8):2421-2435. PubMed ID: 28652304
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TCR-mediated Erk activation does not depend on Sos and Grb2 in peripheral human T cells.
    Warnecke N; Poltorak M; Kowtharapu BS; Arndt B; Stone JC; Schraven B; Simeoni L
    EMBO Rep; 2012 Apr; 13(4):386-91. PubMed ID: 22344067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.