BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 22722337)

  • 1. Control of FLIP(L) expression and TRAIL resistance by the extracellular signal-regulated kinase1/2 pathway in breast epithelial cells.
    Yerbes R; López-Rivas A; Reginato MJ; Palacios C
    Cell Death Differ; 2012 Dec; 19(12):1908-16. PubMed ID: 22722337
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TRAIL induces proliferation of human glioma cells by c-FLIPL-mediated activation of ERK1/2.
    Vilimanovich U; Bumbasirevic V
    Cell Mol Life Sci; 2008 Mar; 65(5):814-26. PubMed ID: 18239851
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity.
    Ricci MS; Jin Z; Dews M; Yu D; Thomas-Tikhonenko A; Dicker DT; El-Deiry WS
    Mol Cell Biol; 2004 Oct; 24(19):8541-55. PubMed ID: 15367674
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Epidermal growth factor receptor-mediated tissue transglutaminase overexpression couples acquired tumor necrosis factor-related apoptosis-inducing ligand resistance and migration through c-FLIP and MMP-9 proteins in lung cancer cells.
    Li Z; Xu X; Bai L; Chen W; Lin Y
    J Biol Chem; 2011 Jun; 286(24):21164-72. PubMed ID: 21525012
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective inhibition of FLICE-like inhibitory protein expression with small interfering RNA oligonucleotides is sufficient to sensitize tumor cells for TRAIL-induced apoptosis.
    Siegmund D; Hadwiger P; Pfizenmaier K; Vornlocher HP; Wajant H
    Mol Med; 2002 Nov; 8(11):725-32. PubMed ID: 12520089
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Progesterone induces apoptosis in TRAIL-resistant ovarian cancer cells by circumventing c-FLIPL overexpression.
    Syed V; Mukherjee K; Godoy-Tundidor S; Ho SM
    J Cell Biochem; 2007 Oct; 102(2):442-52. PubMed ID: 17393432
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.
    Elrod HA; Lin YD; Yue P; Wang X; Lonial S; Khuri FR; Sun SY
    Mol Cancer Ther; 2007 Jul; 6(7):2029-38. PubMed ID: 17604333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells.
    Wang X; Chen W; Zeng W; Bai L; Tesfaigzi Y; Belinsky SA; Lin Y
    Mol Cancer Ther; 2008 May; 7(5):1156-63. PubMed ID: 18483303
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Upregulation of c-FLIP-short in response to TRAIL promotes survival of NSCLC cells, which could be suppressed by inhibition of Ca2+/calmodulin signaling.
    Kaminskyy VO; Surova OV; Piskunova T; Zborovskaya IB; Tchevkina EM; Andera L; Zhivotovsky B
    Cell Death Dis; 2013 Mar; 4(3):e522. PubMed ID: 23470529
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interleukin-8 signaling attenuates TRAIL- and chemotherapy-induced apoptosis through transcriptional regulation of c-FLIP in prostate cancer cells.
    Wilson C; Wilson T; Johnston PG; Longley DB; Waugh DJ
    Mol Cancer Ther; 2008 Sep; 7(9):2649-61. PubMed ID: 18790747
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL.
    Piggott L; Omidvar N; Martí Pérez S; French R; Eberl M; Clarkson RW
    Breast Cancer Res; 2011 Sep; 13(5):R88. PubMed ID: 21914219
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism.
    Ortiz-Ferrón G; Yerbes R; Eramo A; López-Pérez AI; De Maria R; López-Rivas A
    Cell Res; 2008 Jun; 18(6):664-76. PubMed ID: 18458681
    [TBL] [Abstract][Full Text] [Related]  

  • 13. F-box protein 10, an NF-κB-dependent anti-apoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway.
    Ge R; Wang Z; Zeng Q; Xu X; Olumi AF
    Cell Death Differ; 2011 Jul; 18(7):1184-95. PubMed ID: 21252908
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MG-132 sensitizes TRAIL-resistant prostate cancer cells by activating c-Fos/c-Jun heterodimers and repressing c-FLIP(L).
    Li W; Zhang X; Olumi AF
    Cancer Res; 2007 Mar; 67(5):2247-55. PubMed ID: 17332355
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
    Ding J; Polier G; Köhler R; Giaisi M; Krammer PH; Li-Weber M
    J Biol Chem; 2012 Jan; 287(1):641-649. PubMed ID: 22086925
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ku70 acetylation and modulation of c-Myc/ATF4/CHOP signaling axis by SIRT1 inhibition lead to sensitization of HepG2 cells to TRAIL through induction of DR5 and down-regulation of c-FLIP.
    Kim MJ; Hong KS; Kim HB; Lee SH; Bae JH; Kim DW; Dao TT; Oh WK; Kang CD; Kim SH
    Int J Biochem Cell Biol; 2013 Mar; 45(3):711-23. PubMed ID: 23247197
    [TBL] [Abstract][Full Text] [Related]  

  • 17. α-TEA induces apoptosis of human breast cancer cells via activation of TRAIL/DR5 death receptor pathway.
    Yu W; Tiwary R; Li J; Park SK; Jia L; Xiong A; Simmons-Menchaca M; Sanders BG; Kline K
    Mol Carcinog; 2010 Nov; 49(11):964-73. PubMed ID: 20886583
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Persistent c-FLIP(L) expression is necessary and sufficient to maintain resistance to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in prostate cancer.
    Zhang X; Jin TG; Yang H; DeWolf WC; Khosravi-Far R; Olumi AF
    Cancer Res; 2004 Oct; 64(19):7086-91. PubMed ID: 15466204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells.
    Palacios C; Yerbes R; López-Rivas A
    Cancer Res; 2006 Sep; 66(17):8858-69. PubMed ID: 16951203
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cystatin B inhibition of TRAIL-induced apoptosis is associated with the protection of FLIP(L) from degradation by the E3 ligase itch in human melanoma cells.
    Yang F; Tay KH; Dong L; Thorne RF; Jiang CC; Yang E; Tseng HY; Liu H; Christopherson R; Hersey P; Zhang XD
    Cell Death Differ; 2010 Aug; 17(8):1354-67. PubMed ID: 20300110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.