BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

633 related articles for article (PubMed ID: 22723710)

  • 1. Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.
    Martinez TL; Kong L; Wang X; Osborne MA; Crowder ME; Van Meerbeke JP; Xu X; Davis C; Wooley J; Goldhamer DJ; Lutz CM; Rich MM; Sumner CJ
    J Neurosci; 2012 Jun; 32(25):8703-15. PubMed ID: 22723710
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene.
    Park GH; Maeno-Hikichi Y; Awano T; Landmesser LT; Monani UR
    J Neurosci; 2010 Sep; 30(36):12005-19. PubMed ID: 20826664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Motor neuronal repletion of the NMJ organizer, Agrin, modulates the severity of the spinal muscular atrophy disease phenotype in model mice.
    Kim JK; Caine C; Awano T; Herbst R; Monani UR
    Hum Mol Genet; 2017 Jul; 26(13):2377-2385. PubMed ID: 28379354
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Improvement of neuromuscular synaptic phenotypes without enhanced survival and motor function in severe spinal muscular atrophy mice selectively rescued in motor neurons.
    Paez-Colasante X; Seaberg B; Martinez TL; Kong L; Sumner CJ; Rimer M
    PLoS One; 2013; 8(9):e75866. PubMed ID: 24086650
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy.
    Wang ZB; Zhang X; Li XJ
    Cell Res; 2013 Mar; 23(3):378-93. PubMed ID: 23208423
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.
    Murray LM; Comley LH; Thomson D; Parkinson N; Talbot K; Gillingwater TH
    Hum Mol Genet; 2008 Apr; 17(7):949-62. PubMed ID: 18065780
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn
    Reedich EJ; Kalski M; Armijo N; Cox GA; DiDonato CJ
    Exp Neurol; 2021 Mar; 337():113587. PubMed ID: 33382987
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Limited phenotypic effects of selectively augmenting the SMN protein in the neurons of a mouse model of severe spinal muscular atrophy.
    Lee AJ; Awano T; Park GH; Monani UR
    PLoS One; 2012; 7(9):e46353. PubMed ID: 23029491
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy.
    Deguise MO; De Repentigny Y; Tierney A; Beauvais A; Michaud J; Chehade L; Thabet M; Paul B; Reilly A; Gagnon S; Renaud JM; Kothary R
    EBioMedicine; 2020 May; 55():102750. PubMed ID: 32339936
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypothermia improves disease manifestations in SMA mice via SMN augmentation.
    Tsai LK; Chen CL; Tsai YC; Ting CH; Chien YH; Lee NC; Hwu WL
    Hum Mol Genet; 2016 Feb; 25(4):631-41. PubMed ID: 26647309
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.
    Bowerman M; Murray LM; Beauvais A; Pinheiro B; Kothary R
    Neuromuscul Disord; 2012 Mar; 22(3):263-76. PubMed ID: 22071333
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Muscle-specific SMN reduction reveals motor neuron-independent disease in spinal muscular atrophy models.
    Kim JK; Jha NN; Feng Z; Faleiro MR; Chiriboga CA; Wei-Lapierre L; Dirksen RT; Ko CP; Monani UR
    J Clin Invest; 2020 Mar; 130(3):1271-1287. PubMed ID: 32039917
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chronic Pharmacological Increase of Neuronal Activity Improves Sensory-Motor Dysfunction in Spinal Muscular Atrophy Mice.
    Simon CM; Blanco-Redondo B; Buettner JM; Pagiazitis JG; Fletcher EV; Sime Longang JK; Mentis GZ
    J Neurosci; 2021 Jan; 41(2):376-389. PubMed ID: 33219005
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reversible molecular pathology of skeletal muscle in spinal muscular atrophy.
    Mutsaers CA; Wishart TM; Lamont DJ; Riessland M; Schreml J; Comley LH; Murray LM; Parson SH; Lochmüller H; Wirth B; Talbot K; Gillingwater TH
    Hum Mol Genet; 2011 Nov; 20(22):4334-44. PubMed ID: 21840928
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy.
    Kariya S; Park GH; Maeno-Hikichi Y; Leykekhman O; Lutz C; Arkovitz MS; Landmesser LT; Monani UR
    Hum Mol Genet; 2008 Aug; 17(16):2552-69. PubMed ID: 18492800
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synaptic withdrawal following nerve injury is influenced by postnatal maturity, muscle-specific properties, and the presence of underlying pathology in mice.
    Mole AJ; Bell S; Thomson AK; Dissanayake KN; Ribchester RR; Murray LM
    J Anat; 2020 Aug; 237(2):263-274. PubMed ID: 32311115
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice.
    Tsai LK; Tsai MS; Ting CH; Li H
    J Mol Med (Berl); 2008 Nov; 86(11):1243-54. PubMed ID: 18649067
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
    Monani UR; Sendtner M; Coovert DD; Parsons DW; Andreassi C; Le TT; Jablonka S; Schrank B; Rossoll W; Prior TW; Morris GE; Burghes AH
    Hum Mol Genet; 2000 Feb; 9(3):333-9. PubMed ID: 10655541
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins.
    Huo Q; Kayikci M; Odermatt P; Meyer K; Michels O; Saxena S; Ule J; Schümperli D
    RNA Biol; 2014; 11(11):1430-46. PubMed ID: 25692239
    [TBL] [Abstract][Full Text] [Related]  

  • 20. What Genetics Has Told Us and How It Can Inform Future Experiments for Spinal Muscular Atrophy, a Perspective.
    Blatnik AJ; McGovern VL; Burghes AHM
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445199
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.