BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 22728709)

  • 1. Pharmacological inhibition of ATM by KU55933 stimulates ATM transcription.
    Khalil HS; Tummala H; Hupp TR; Zhelev N
    Exp Biol Med (Maywood); 2012 Jun; 237(6):622-34. PubMed ID: 22728709
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Persistence of unrepaired DNA double strand breaks caused by inhibition of ATM does not lead to radio-sensitisation in the absence of NF-κB activation.
    Veuger SJ; Durkacz BW
    DNA Repair (Amst); 2011 Feb; 10(2):235-44. PubMed ID: 21144805
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clioquinol induces DNA double-strand breaks, activation of ATM, and subsequent activation of p53 signaling.
    Katsuyama M; Iwata K; Ibi M; Matsuno K; Matsumoto M; Yabe-Nishimura C
    Toxicology; 2012 Sep; 299(1):55-9. PubMed ID: 22627294
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1.
    Yoon JH; Ahn SG; Lee BH; Jung SH; Oh SH
    Biochem Pharmacol; 2012 Mar; 83(6):747-57. PubMed ID: 22226932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
    Powers JT; Hong S; Mayhew CN; Rogers PM; Knudsen ES; Johnson DG
    Mol Cancer Res; 2004 Apr; 2(4):203-14. PubMed ID: 15140942
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response.
    Golding SE; Rosenberg E; Neill S; Dent P; Povirk LF; Valerie K
    Cancer Res; 2007 Feb; 67(3):1046-53. PubMed ID: 17283137
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ataxia telangiectasia mutated and p21CIP1 modulate cell survival of drug-induced senescent tumor cells: implications for chemotherapy.
    Crescenzi E; Palumbo G; de Boer J; Brady HJ
    Clin Cancer Res; 2008 Mar; 14(6):1877-87. PubMed ID: 18347191
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress.
    Kirshner J; Jobling MF; Pajares MJ; Ravani SA; Glick AB; Lavin MJ; Koslov S; Shiloh Y; Barcellos-Hoff MH
    Cancer Res; 2006 Nov; 66(22):10861-9. PubMed ID: 17090522
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription.
    Moiola C; De Luca P; Cotignola J; Gardner K; Vazquez E; De Siervi A
    Cell Physiol Biochem; 2012; 30(3):596-608. PubMed ID: 22832221
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway.
    Pamment J; Ramsay E; Kelleher M; Dornan D; Ball KL
    Oncogene; 2002 Nov; 21(51):7776-85. PubMed ID: 12420214
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATM-dependent and -independent dynamics of the nuclear phosphoproteome after DNA damage.
    Bensimon A; Schmidt A; Ziv Y; Elkon R; Wang SY; Chen DJ; Aebersold R; Shiloh Y
    Sci Signal; 2010 Dec; 3(151):rs3. PubMed ID: 21139141
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of a high-content high-throughput screening assay for the discovery of ATM signaling inhibitors.
    Bardelle C; Boros J
    J Biomol Screen; 2012 Aug; 17(7):912-20. PubMed ID: 22653913
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM.
    Peng Y; Woods RG; Beamish H; Ye R; Lees-Miller SP; Lavin MF; Bedford JS
    Cancer Res; 2005 Mar; 65(5):1670-7. PubMed ID: 15753361
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.
    Goldstine JV; Nahas S; Gamo K; Gartler SM; Hansen RS; Roelfsema JH; Gatti RA; Marahrens Y
    DNA Repair (Amst); 2006 Apr; 5(4):432-43. PubMed ID: 16426903
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sodium salicylate acts through direct inhibition of phosphoinositide 3-kinase-like kinases to modulate topoisomerase-mediated DNA damage responses.
    Fan JR; Huang TH; Wen CY; Shen TL; Li TK
    Eur J Pharmacol; 2010 Jul; 638(1-3):13-20. PubMed ID: 20406630
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells.
    Korwek Z; Sewastianik T; Bielak-Zmijewska A; Mosieniak G; Alster O; Moreno-Villanueva M; Burkle A; Sikora E
    DNA Repair (Amst); 2012 Nov; 11(11):864-73. PubMed ID: 23058634
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATM-deficient human fibroblast cells are resistant to low levels of DNA double-strand break induced apoptosis and subsequently undergo drug-induced premature senescence.
    Park J; Jo YH; Cho CH; Choe W; Kang I; Baik HH; Yoon KS
    Biochem Biophys Res Commun; 2013 Jan; 430(1):429-35. PubMed ID: 23178571
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional characterization connects individual patient mutations in ataxia telangiectasia mutated (ATM) with dysfunction of specific DNA double-strand break-repair signaling pathways.
    Keimling M; Volcic M; Csernok A; Wieland B; Dörk T; Wiesmüller L
    FASEB J; 2011 Nov; 25(11):3849-60. PubMed ID: 21778326
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway.
    Lim DS; Kim ST; Xu B; Maser RS; Lin J; Petrini JH; Kastan MB
    Nature; 2000 Apr; 404(6778):613-7. PubMed ID: 10766245
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.
    Horejsí Z; Falck J; Bakkenist CJ; Kastan MB; Lukas J; Bartek J
    Oncogene; 2004 Apr; 23(17):3122-7. PubMed ID: 15048089
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.