232 related articles for article (PubMed ID: 22729780)
1. Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo.
Sarkar S; Dutta D; Samanta SK; Bhattacharya K; Pal BC; Li J; Datta K; Mandal C; Mandal C
Int J Cancer; 2013 Feb; 132(3):695-706. PubMed ID: 22729780
[TBL] [Abstract][Full Text] [Related]
2. A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells.
Zhang T; Hamza A; Cao X; Wang B; Yu S; Zhan CG; Sun D
Mol Cancer Ther; 2008 Jan; 7(1):162-70. PubMed ID: 18202019
[TBL] [Abstract][Full Text] [Related]
3. Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.
Li Y; Karagöz GE; Seo YH; Zhang T; Jiang Y; Yu Y; Duarte AM; Schwartz SJ; Boelens R; Carroll K; Rüdiger SG; Sun D
J Nutr Biochem; 2012 Dec; 23(12):1617-26. PubMed ID: 22444872
[TBL] [Abstract][Full Text] [Related]
4. Simvastatin functions as a heat shock protein 90 inhibitor against triple-negative breast cancer.
Kou X; Jiang X; Liu H; Wang X; Sun F; Han J; Fan J; Feng G; Lin Z; Jiang L; Yang Y
Cancer Sci; 2018 Oct; 109(10):3272-3284. PubMed ID: 30039622
[TBL] [Abstract][Full Text] [Related]
5. Withaferin A targets heat shock protein 90 in pancreatic cancer cells.
Yu Y; Hamza A; Zhang T; Gu M; Zou P; Newman B; Li Y; Gunatilaka AA; Zhan CG; Sun D
Biochem Pharmacol; 2010 Feb; 79(4):542-51. PubMed ID: 19769945
[TBL] [Abstract][Full Text] [Related]
6. Discovery of a covalent inhibitor of heat shock protein 90 with antitumor activity that blocks the co-chaperone binding via C-terminal modification.
Li L; Chen N; Xia D; Xu S; Dai W; Tong Y; Wang L; Jiang Z; You Q; Xu X
Cell Chem Biol; 2021 Oct; 28(10):1446-1459.e6. PubMed ID: 33932325
[TBL] [Abstract][Full Text] [Related]
7. Mahanine drives pancreatic adenocarcinoma cells into endoplasmic reticular stress-mediated apoptosis through modulating sialylation process and Ca
Sarkar Bhattacharya S; Mandal C; Albiez RS; Samanta SK; Mandal C
Sci Rep; 2018 Mar; 8(1):3911. PubMed ID: 29500369
[TBL] [Abstract][Full Text] [Related]
8. Structure-activity relationship (SAR) of withanolides to inhibit Hsp90 for its activity in pancreatic cancer cells.
Gu M; Yu Y; Gunaherath GM; Gunatilaka AA; Li D; Sun D
Invest New Drugs; 2014 Feb; 32(1):68-74. PubMed ID: 23887853
[TBL] [Abstract][Full Text] [Related]
9. Hsp90/Cdc37 chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A.
Grover A; Shandilya A; Agrawal V; Pratik P; Bhasme D; Bisaria VS; Sundar D
BMC Bioinformatics; 2011 Feb; 12 Suppl 1(Suppl 1):S30. PubMed ID: 21342561
[TBL] [Abstract][Full Text] [Related]
10. DCZ3112, a novel Hsp90 inhibitor, exerts potent antitumor activity against HER2-positive breast cancer through disruption of Hsp90-Cdc37 interaction.
Chen X; Liu P; Wang Q; Li Y; Fu L; Fu H; Zhu J; Chen Z; Zhu W; Xie C; Lou L
Cancer Lett; 2018 Oct; 434():70-80. PubMed ID: 30017966
[TBL] [Abstract][Full Text] [Related]
11. Targeting CDC37: an alternative, kinase-directed strategy for disruption of oncogenic chaperoning.
Smith JR; Workman P
Cell Cycle; 2009 Feb; 8(3):362-72. PubMed ID: 19177013
[TBL] [Abstract][Full Text] [Related]
12. Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.
Ota A; Zhang J; Ping P; Han J; Wang Y
Circ Res; 2010 Apr; 106(8):1404-12. PubMed ID: 20299663
[TBL] [Abstract][Full Text] [Related]
13. Tubocapsenolide A, a novel withanolide, inhibits proliferation and induces apoptosis in MDA-MB-231 cells by thiol oxidation of heat shock proteins.
Chen WY; Chang FR; Huang ZY; Chen JH; Wu YC; Wu CC
J Biol Chem; 2008 Jun; 283(25):17184-93. PubMed ID: 18442981
[TBL] [Abstract][Full Text] [Related]
14. Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins.
Li R; Yuan F; Fu W; Zhang L; Zhang N; Wang Y; Ma K; Li X; Wang L; Zhu WG; Zhao Y
J Biol Chem; 2017 Feb; 292(7):2830-2841. PubMed ID: 28073914
[TBL] [Abstract][Full Text] [Related]
15. FW-04-806 inhibits proliferation and induces apoptosis in human breast cancer cells by binding to N-terminus of Hsp90 and disrupting Hsp90-Cdc37 complex formation.
Huang W; Ye M; Zhang LR; Wu QD; Zhang M; Xu JH; Zheng W
Mol Cancer; 2014 Jun; 13():150. PubMed ID: 24927996
[TBL] [Abstract][Full Text] [Related]
16. Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer.
Wang L; Zhang L; Li L; Jiang J; Zheng Z; Shang J; Wang C; Chen W; Bao Q; Xu X; Jiang Z; Zhang J; You Q
Sci Adv; 2019 Sep; 5(9):eaax2277. PubMed ID: 31555737
[TBL] [Abstract][Full Text] [Related]
17. Characterization of celastrol to inhibit hsp90 and cdc37 interaction.
Zhang T; Li Y; Yu Y; Zou P; Jiang Y; Sun D
J Biol Chem; 2009 Dec; 284(51):35381-9. PubMed ID: 19858214
[TBL] [Abstract][Full Text] [Related]
18. ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system.
Polier S; Samant RS; Clarke PA; Workman P; Prodromou C; Pearl LH
Nat Chem Biol; 2013 May; 9(5):307-12. PubMed ID: 23502424
[TBL] [Abstract][Full Text] [Related]
19. Discovery of 18β-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance.
Jin L; Huang R; Huang X; Zhang B; Ji M; Wang H
Bioorg Med Chem; 2018 May; 26(8):1759-1775. PubMed ID: 29486954
[TBL] [Abstract][Full Text] [Related]
20. Antiproliferative effect of HSP90 inhibitor Y306zh against pancreatic cancer is mediated by interruption of AKT and MAPK signaling pathways.
Xue N; Jin J; Liu D; Yan R; Zhang S; Yu X; Chen X
Curr Cancer Drug Targets; 2014; 14(7):671-83. PubMed ID: 25219422
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]