218 related articles for article (PubMed ID: 22729867)
1. Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter.
Latha K; Li M; Chumbalkar V; Gururaj A; Hwang Y; Dakeng S; Sawaya R; Aldape K; Cavenee WK; Bogler O; Furnari FB
Int J Cancer; 2013 Feb; 132(3):509-20. PubMed ID: 22729867
[TBL] [Abstract][Full Text] [Related]
2. Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.
Hu J; Jo M; Cavenee WK; Furnari F; VandenBerg SR; Gonias SL
Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15984-9. PubMed ID: 21896743
[TBL] [Abstract][Full Text] [Related]
3. Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ΔEGFR.
Chumbalkar V; Latha K; Hwang Y; Maywald R; Hawley L; Sawaya R; Diao L; Baggerly K; Cavenee WK; Furnari FB; Bogler O
J Proteome Res; 2011 Mar; 10(3):1343-52. PubMed ID: 21214269
[TBL] [Abstract][Full Text] [Related]
4. Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases.
Nagane M; Levitzki A; Gazit A; Cavenee WK; Huang HJ
Proc Natl Acad Sci U S A; 1998 May; 95(10):5724-9. PubMed ID: 9576951
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis.
Feng H; Hu B; Jarzynka MJ; Li Y; Keezer S; Johns TG; Tang CK; Hamilton RL; Vuori K; Nishikawa R; Sarkaria JN; Fenton T; Cheng T; Furnari FB; Cavenee WK; Cheng SY
Proc Natl Acad Sci U S A; 2012 Feb; 109(8):3018-23. PubMed ID: 22323579
[TBL] [Abstract][Full Text] [Related]
6. Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells.
Fox EM; Bernaciak TM; Wen J; Weaver AM; Shupnik MA; Silva CM
Mol Endocrinol; 2008 Aug; 22(8):1781-96. PubMed ID: 18550772
[TBL] [Abstract][Full Text] [Related]
7. Regulation of HGF expression by ΔEGFR-mediated c-Met activation in glioblastoma cells.
Garnett J; Chumbalkar V; Vaillant B; Gururaj AE; Hill KS; Latha K; Yao J; Priebe W; Colman H; Elferink LA; Bogler O
Neoplasia; 2013 Jan; 15(1):73-84. PubMed ID: 23359207
[TBL] [Abstract][Full Text] [Related]
8. Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression.
Hung LY; Tseng JT; Lee YC; Xia W; Wang YN; Wu ML; Chuang YH; Lai CH; Chang WC
Nucleic Acids Res; 2008 Aug; 36(13):4337-51. PubMed ID: 18586824
[TBL] [Abstract][Full Text] [Related]
9. Signal transducer and activator of transcription 5b drives malignant progression in a PDGFB-dependent proneural glioma model by suppressing apoptosis.
Gressot LV; Doucette TA; Yang Y; Fuller GN; Heimberger AB; Bögler O; Rao A; Latha K; Rao G
Int J Cancer; 2015 May; 136(9):2047-54. PubMed ID: 25302990
[TBL] [Abstract][Full Text] [Related]
10. EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival.
Roos A; Dhruv HD; Peng S; Inge LJ; Tuncali S; Pineda M; Millard N; Mayo Z; Eschbacher JM; Loftus JC; Winkles JA; Tran NL
Mol Cancer Res; 2018 Jul; 16(7):1185-1195. PubMed ID: 29724813
[TBL] [Abstract][Full Text] [Related]
11. Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients.
Lu KV; Zhu S; Cvrljevic A; Huang TT; Sarkaria S; Ahkavan D; Dang J; Dinca EB; Plaisier SB; Oderberg I; Lee Y; Chen Z; Caldwell JS; Xie Y; Loo JA; Seligson D; Chakravari A; Lee FY; Weinmann R; Cloughesy TF; Nelson SF; Bergers G; Graeber T; Furnari FB; James CD; Cavenee WK; Johns TG; Mischel PS
Cancer Res; 2009 Sep; 69(17):6889-98. PubMed ID: 19690143
[TBL] [Abstract][Full Text] [Related]
12. Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor.
Mishima K; Johns TG; Luwor RB; Scott AM; Stockert E; Jungbluth AA; Ji XD; Suvarna P; Voland JR; Old LJ; Huang HJ; Cavenee WK
Cancer Res; 2001 Jul; 61(14):5349-54. PubMed ID: 11454673
[TBL] [Abstract][Full Text] [Related]
13. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma.
Fan QW; Cheng CK; Gustafson WC; Charron E; Zipper P; Wong RA; Chen J; Lau J; Knobbe-Thomsen C; Weller M; Jura N; Reifenberger G; Shokat KM; Weiss WA
Cancer Cell; 2013 Oct; 24(4):438-49. PubMed ID: 24135280
[TBL] [Abstract][Full Text] [Related]
14. Forced dimerization increases the activity of ΔEGFR/EGFRvIII and enhances its oncogenicity.
Hwang Y; Chumbalkar V; Latha K; Bogler O
Mol Cancer Res; 2011 Sep; 9(9):1199-208. PubMed ID: 21775422
[TBL] [Abstract][Full Text] [Related]
15. Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways.
Kirito K; Watanabe T; Sawada K; Endo H; Ozawa K; Komatsu N
J Biol Chem; 2002 Mar; 277(10):8329-37. PubMed ID: 11756417
[TBL] [Abstract][Full Text] [Related]
16. Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.
Hu J; Muller KA; Furnari FB; Cavenee WK; VandenBerg SR; Gonias SL
Oncogene; 2015 Jul; 34(31):4078-88. PubMed ID: 25347738
[TBL] [Abstract][Full Text] [Related]
17. EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway.
Bonavia R; Inda MM; Vandenberg S; Cheng SY; Nagane M; Hadwiger P; Tan P; Sah DW; Cavenee WK; Furnari FB
Oncogene; 2012 Sep; 31(36):4054-66. PubMed ID: 22139077
[TBL] [Abstract][Full Text] [Related]
18. Access to the nucleus and functional association with c-Myc is required for the full oncogenic potential of ΔEGFR/EGFRvIII.
Gururaj AE; Gibson L; Panchabhai S; Bai M; Manyam G; Lu Y; Latha K; Rojas ML; Hwang Y; Liang S; Bogler O
J Biol Chem; 2013 Feb; 288(5):3428-38. PubMed ID: 23250739
[TBL] [Abstract][Full Text] [Related]
19. Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6.
Weaver AM; Silva CM
Breast Cancer Res; 2007; 9(6):R79. PubMed ID: 17997837
[TBL] [Abstract][Full Text] [Related]
20. Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas.
Narita Y; Nagane M; Mishima K; Huang HJ; Furnari FB; Cavenee WK
Cancer Res; 2002 Nov; 62(22):6764-9. PubMed ID: 12438278
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]