BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 22732416)

  • 1. A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2.
    Kim HL; Jeon KH; Jun KY; Choi Y; Kim DK; Na Y; Kwon Y
    Cancer Lett; 2012 Dec; 325(1):72-9. PubMed ID: 22732416
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dithiiranylmethyloxy azaxanthone shows potent anti-tumor activity via suppression of HER2 expression and HER2-mediated signals in HER2-overexpressing breast cancer cells.
    Nam JM; Jeon KH; Kwon H; Lee E; Jun KY; Jin YB; Lee YS; Na Y; Kwon Y
    Eur J Pharm Sci; 2013 Oct; 50(2):181-90. PubMed ID: 23835029
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Magnolol down-regulates HER2 gene expression, leading to inhibition of HER2-mediated metastatic potential in ovarian cancer cells.
    Chuang TC; Hsu SC; Cheng YT; Shao WS; Wu K; Fang GS; Ou CC; Wang V
    Cancer Lett; 2011 Dec; 311(1):11-9. PubMed ID: 21757288
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
    Hofland K; Petersen BO; Falck J; Helin K; Jensen PB; Sehested M
    Clin Cancer Res; 2000 Apr; 6(4):1488-97. PubMed ID: 10778981
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cycle arrest and apoptosis in MDA-MB-231/Her2 cells induced by curcumin.
    Sun SH; Huang HC; Huang C; Lin JK
    Eur J Pharmacol; 2012 Sep; 690(1-3):22-30. PubMed ID: 22705896
    [TBL] [Abstract][Full Text] [Related]  

  • 7. E1A sensitizes HER2/neu-overexpressing Ewing's sarcoma cells to topoisomerase II-targeting anticancer drugs.
    Zhou Z; Jia SF; Hung MC; Kleinerman ES
    Cancer Res; 2001 Apr; 61(8):3394-8. PubMed ID: 11309298
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Testican-1-mediated epithelial-mesenchymal transition signaling confers acquired resistance to lapatinib in HER2-positive gastric cancer.
    Kim HP; Han SW; Song SH; Jeong EG; Lee MY; Hwang D; Im SA; Bang YJ; Kim TY
    Oncogene; 2014 Jun; 33(25):3334-41. PubMed ID: 23873022
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of sensitivity to doxorubicin and etoposide by transfection of MCF-7 breast cancer cells with heregulin beta-2.
    Harris LN; Yang L; Tang C; Yang D; Lupu R
    Clin Cancer Res; 1998 Apr; 4(4):1005-12. PubMed ID: 9563896
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human epidermal growth factor receptor 2 regulates angiopoietin-2 expression in breast cancer via AKT and mitogen-activated protein kinase pathways.
    Niu G; Carter WB
    Cancer Res; 2007 Feb; 67(4):1487-93. PubMed ID: 17308086
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SUCI02 inhibits the erbB-2 tyrosine kinase receptor signaling pathway and arrests the cell cycle in G1 phase in breast cancer cells.
    Zhu XF; Wang JS; Cai LL; Zeng YX; Yang D
    Cancer Sci; 2006 Jan; 97(1):84-9. PubMed ID: 16367926
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Contribution of c-erbB-2 and topoisomerase IIalpha to chemoresistance in ovarian cancer.
    Hengstler JG; Lange J; Kett A; Dornhöfer N; Meinert R; Arand M; Knapstein PG; Becker R; Oesch F; Tanner B
    Cancer Res; 1999 Jul; 59(13):3206-14. PubMed ID: 10397267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells.
    Chinni SR; Li Y; Upadhyay S; Koppolu PK; Sarkar FH
    Oncogene; 2001 May; 20(23):2927-36. PubMed ID: 11420705
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sodium salicylate is a novel catalytic inhibitor of human DNA topoisomerase II alpha.
    Bau JT; Kurz EU
    Biochem Pharmacol; 2011 Feb; 81(3):345-54. PubMed ID: 20959117
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Topoisomerase IIalpha gene amplification in gastric carcinomas: correlation with the HER2 gene. An immunohistochemical, immunoblotting, and multicolor fluorescence in situ hybridization study.
    Kanta SY; Yamane T; Dobashi Y; Mitsui F; Kono K; Ooi A
    Hum Pathol; 2006 Oct; 37(10):1333-43. PubMed ID: 16949920
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cleistanthoside A tetraacetate-induced DNA damage leading to cell cycle arrest and apoptosis with the involvement of p53 in lung cancer cells.
    Wanitchakool P; Jariyawat S; Suksen K; Soorukram D; Tuchinda P; Piyachaturawat P
    Eur J Pharmacol; 2012 Dec; 696(1-3):35-42. PubMed ID: 23041153
    [TBL] [Abstract][Full Text] [Related]  

  • 17. All-trans retinoic acid suppresses topoisomerase IIα through the proteasomal pathway.
    Li X; Li Y; Shen X; Fu S; Han S; Feng Q
    Anticancer Drugs; 2015 Aug; 26(7):737-46. PubMed ID: 25946380
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Her-2/neu and topoisomerase IIα in advanced breast cancer: a comprehensive FISH analysis of 245 cases.
    Engelstaedter V; Schiffers J; Kahlert S; Mainka P; Engel J; Kirchner T; Diebold J; Mayr D
    Diagn Mol Pathol; 2012 Jun; 21(2):77-83. PubMed ID: 22555090
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nitric oxide inhibits gastric cancer cell growth through the modulation of the Akt pathway.
    Sang J; Chen Y; Tao Y
    Mol Med Rep; 2011; 4(6):1163-7. PubMed ID: 21769431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Classical lobular breast carcinoma consistently lacks topoisomerase-IIα gene amplification: implications for the tailored use of anthracycline-based chemotherapies.
    Brunello E; Brunelli M; Manfrin E; Nottegar A; Bersani S; Vergine M; Molino A; Fiorio E; Chilosi M; Gobbo S; Martignoni G; Bonetti F
    Histopathology; 2012 Feb; 60(3):482-8. PubMed ID: 22168383
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.