BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 22733131)

  • 1. Essential, non-redundant roles of B-Raf and Raf-1 in Ras-driven skin tumorigenesis.
    Kern F; Doma E; Rupp C; Niault T; Baccarini M
    Oncogene; 2013 May; 32(19):2483-92. PubMed ID: 22733131
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).
    Karreth FA; DeNicola GM; Winter SP; Tuveson DA
    Mol Cell; 2009 Nov; 36(3):477-86. PubMed ID: 19917255
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells.
    Fan F; Feng L; He J; Wang X; Jiang X; Zhang Y; Wang Z; Chen Y
    Carcinogenesis; 2008 Jun; 29(6):1157-63. PubMed ID: 18515281
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RAF protein-serine/threonine kinases: structure and regulation.
    Roskoski R
    Biochem Biophys Res Commun; 2010 Aug; 399(3):313-7. PubMed ID: 20674547
    [TBL] [Abstract][Full Text] [Related]  

  • 5. B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic beta-cell carcinogenesis.
    Sobczak I; Galabova-Kovacs G; Sadzak I; Kren A; Christofori G; Baccarini M
    Oncogene; 2008 Aug; 27(35):4779-87. PubMed ID: 18490924
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia.
    Zebisch A; Staber PB; Delavar A; Bodner C; Hiden K; Fischereder K; Janakiraman M; Linkesch W; Auner HW; Emberger W; Windpassinger C; Schimek MG; Hoefler G; Troppmair J; Sill H
    Cancer Res; 2006 Apr; 66(7):3401-8. PubMed ID: 16585161
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors.
    Ikenoue T; Hikiba Y; Kanai F; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Aragaki J; Matsumura M; Kawabe T; Omata M
    Cancer Res; 2003 Dec; 63(23):8132-7. PubMed ID: 14678966
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Requirement of B-Raf, C-Raf, and A-Raf for the growth and survival of mouse embryonic stem cells.
    Guo W; Hao B; Wang Q; Lu Y; Yue J
    Exp Cell Res; 2013 Nov; 319(18):2801-11. PubMed ID: 24051329
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo.
    Ouyang B; Knauf JA; Smith EP; Zhang L; Ramsey T; Yusuff N; Batt D; Fagin JA
    Clin Cancer Res; 2006 Mar; 12(6):1785-93. PubMed ID: 16551863
    [TBL] [Abstract][Full Text] [Related]  

  • 10. c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma.
    Blasco RB; Francoz S; Santamaría D; Cañamero M; Dubus P; Charron J; Baccarini M; Barbacid M
    Cancer Cell; 2011 May; 19(5):652-63. PubMed ID: 21514245
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth.
    Zanucco E; El-Nikhely N; Götz R; Weidmann K; Pfeiffer V; Savai R; Seeger W; Ullrich A; Rapp UR
    J Biol Chem; 2014 Sep; 289(39):26804-26816. PubMed ID: 25096573
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.
    Adler V; Qu Y; Smith SJ; Izotova L; Pestka S; Kung HF; Lin M; Friedman FK; Chie L; Chung D; Boutjdir M; Pincus MR
    Biochemistry; 2005 Aug; 44(32):10784-95. PubMed ID: 16086581
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation and role of Raf-1/B-Raf heterodimerization.
    Rushworth LK; Hindley AD; O'Neill E; Kolch W
    Mol Cell Biol; 2006 Mar; 26(6):2262-72. PubMed ID: 16508002
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Skin tumorigenesis stimulated by Raf inhibitors relies upon Raf functions that are dependent and independent of ERK.
    Doma E; Rupp C; Varga A; Kern F; Riegler B; Baccarini M
    Cancer Res; 2013 Dec; 73(23):6926-37. PubMed ID: 24129679
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.
    Dorard C; Estrada C; Barbotin C; Larcher M; Garancher A; Leloup J; Beermann F; Baccarini M; Pouponnot C; Larue L; Eychène A; Druillennec S
    Nat Commun; 2017 May; 8():15262. PubMed ID: 28497782
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Leukemia inhibitory factor can mediate Ras/Raf/MEK/ERK-induced growth inhibitory signaling in medullary thyroid cancer cells.
    Arthan D; Hong SK; Park JI
    Cancer Lett; 2010 Nov; 297(1):31-41. PubMed ID: 20570039
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Raf-1 addiction in Ras-induced skin carcinogenesis.
    Ehrenreiter K; Kern F; Velamoor V; Meissl K; Galabova-Kovacs G; Sibilia M; Baccarini M
    Cancer Cell; 2009 Aug; 16(2):149-60. PubMed ID: 19647225
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf.
    Mercer K; Chiloeches A; Hüser M; Kiernan M; Marais R; Pritchard C
    Oncogene; 2002 Jan; 21(3):347-55. PubMed ID: 11821947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deficiency of kinase suppressor of Ras1 prevents oncogenic ras signaling in mice.
    Lozano J; Xing R; Cai Z; Jensen HL; Trempus C; Mark W; Cannon R; Kolesnick R
    Cancer Res; 2003 Jul; 63(14):4232-8. PubMed ID: 12874031
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.