BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

649 related articles for article (PubMed ID: 22733434)

  • 1. Long-term arsenic exposure induces histone H3 Lys9 dimethylation without altering DNA methylation in the promoter region of p16(INK4a) and down-regulates its expression in the liver of mice.
    Suzuki T; Nohara K
    J Appl Toxicol; 2013 Sep; 33(9):951-8. PubMed ID: 22733434
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.
    Hinshelwood RA; Melki JR; Huschtscha LI; Paul C; Song JZ; Stirzaker C; Reddel RR; Clark SJ
    Hum Mol Genet; 2009 Aug; 18(16):3098-109. PubMed ID: 19477956
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications.
    Zhang C; Li H; Wang Y; Liu W; Zhang Q; Zhang T; Zhang X; Han B; Zhou G
    J Hepatol; 2010 Nov; 53(5):889-95. PubMed ID: 20675009
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Carcinogen exposure and gene promoter hypermethylation in bladder cancer.
    Marsit CJ; Karagas MR; Danaee H; Liu M; Andrew A; Schned A; Nelson HH; Kelsey KT
    Carcinogenesis; 2006 Jan; 27(1):112-6. PubMed ID: 15987713
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chronic oral exposure to inorganic arsenate interferes with methylation status of p16INK4a and RASSF1A and induces lung cancer in A/J mice.
    Cui X; Wakai T; Shirai Y; Hatakeyama K; Hirano S
    Toxicol Sci; 2006 Jun; 91(2):372-81. PubMed ID: 16543296
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9a.
    Zhang X; Wu J; Choiniere J; Yang Z; Huang Y; Bennett J; Wang L
    Toxicol Appl Pharmacol; 2016 Aug; 304():42-7. PubMed ID: 27217333
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Arsenic activates the expression of 3β-HSD in mouse Leydig cells through repression of histone H3K9 methylation.
    Alamdar A; Xi G; Huang Q; Tian M; Eqani SAMAS; Shen H
    Toxicol Appl Pharmacol; 2017 Jul; 326():7-14. PubMed ID: 28414027
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comprehensive epigenetic analysis using oral rinse samples: a pilot study.
    Kusumoto T; Hamada T; Yamada N; Nagata S; Kanmura Y; Houjou I; Kamikawa Y; Yonezawa S; Sugihara K
    J Oral Maxillofac Surg; 2012 Jun; 70(6):1486-94. PubMed ID: 21821326
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of acute dichlorodiphenyltrichloroethane exposure on hypermethylation status and down-regulation of p53 and p16INK4a genes in rat liver.
    Kostka G; Urbanek-Olejnik K; Liszewska M; Winczura A
    Environ Toxicol; 2016 May; 31(5):584-92. PubMed ID: 25410620
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma.
    Zhang YJ; Ahsan H; Chen Y; Lunn RM; Wang LY; Chen SY; Lee PH; Chen CJ; Santella RM
    Mol Carcinog; 2002 Oct; 35(2):85-92. PubMed ID: 12325038
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells.
    Zhang C; Li H; Zhou G; Zhang Q; Zhang T; Li J; Zhang J; Hou J; Liew CT; Yin D
    J Pathol; 2007 Jun; 212(2):134-42. PubMed ID: 17471463
    [TBL] [Abstract][Full Text] [Related]  

  • 12. H3K9me-enhanced DNA hypermethylation of the p16INK4a gene: an epigenetic signature for spontaneous transformation of rat mesenchymal stem cells.
    Zheng Y; He L; Wan Y; Song J
    Stem Cells Dev; 2013 Jan; 22(2):256-67. PubMed ID: 22873822
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells.
    Lee SH; Kim J; Kim WH; Lee YM
    Oncogene; 2009 Jan; 28(2):184-94. PubMed ID: 18850007
    [TBL] [Abstract][Full Text] [Related]  

  • 14. G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription.
    Tachibana M; Matsumura Y; Fukuda M; Kimura H; Shinkai Y
    EMBO J; 2008 Oct; 27(20):2681-90. PubMed ID: 18818694
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo.
    Park KE; Johnson CM; Cabot RA
    Reprod Fertil Dev; 2012; 24(6):813-21. PubMed ID: 22781932
    [TBL] [Abstract][Full Text] [Related]  

  • 16. H3K27 trimethylation is an early epigenetic event of p16INK4a silencing for regaining tumorigenesis in fusion reprogrammed hepatoma cells.
    Yao JY; Zhang L; Zhang X; He ZY; Ma Y; Hui LJ; Wang X; Hu YP
    J Biol Chem; 2010 Jun; 285(24):18828-37. PubMed ID: 20382980
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells.
    Zhu WG; Dai Z; Ding H; Srinivasan K; Hall J; Duan W; Villalona-Calero MA; Plass C; Otterson GA
    Oncogene; 2001 Nov; 20(53):7787-96. PubMed ID: 11753657
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice.
    Subbanna S; Nagre NN; Shivakumar M; Umapathy NS; Psychoyos D; Basavarajappa BS
    Neuroscience; 2014 Jan; 258():422-32. PubMed ID: 24300108
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [DNA methylation and histone modification relate to RASSF1A gene deletion in laryngeal carcinoma tissues].
    Yang J; Ji WY; Qu YR; He LX; Zhao XD; Jin MZ
    Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2011 Apr; 46(4):308-12. PubMed ID: 21624251
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glutathione S-transferase P1 and NADPH quinone oxidoreductase polymorphisms are associated with aberrant promoter methylation of P16(INK4a) and O(6)-methylguanine-DNA methyltransferase in sputum.
    Gilliland FD; Harms HJ; Crowell RE; Li YF; Willink R; Belinsky SA
    Cancer Res; 2002 Apr; 62(8):2248-52. PubMed ID: 11956078
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.