These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 22733548)

  • 1. Protein interface remodeling in a chemically induced protein dimer.
    White BR; Carlson JC; Kerns JL; Wagner CR
    J Mol Recognit; 2012 Jul; 25(7):393-403. PubMed ID: 22733548
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fluorescent biphenyl derivatives of phenylalanine suitable for protein modification.
    Chen S; Fahmi NE; Bhattacharya C; Wang L; Jin Y; Benkovic SJ; Hecht SM
    Biochemistry; 2013 Nov; 52(47):8580-9. PubMed ID: 24152169
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In Silico Study Identified Methotrexate Analog as Potential Inhibitor of Drug Resistant Human Dihydrofolate Reductase for Cancer Therapeutics.
    Rana RM; Rampogu S; Abid NB; Zeb A; Parate S; Lee G; Yoon S; Kim Y; Kim D; Lee KW
    Molecules; 2020 Jul; 25(15):. PubMed ID: 32752079
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemically induced self-assembly of enzyme nanorings.
    White BR; Li Q; Wagner CR
    Methods Mol Biol; 2011; 743():17-26. PubMed ID: 21553179
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of codon 22 mutations on substrate and inhibitor binding for human dihydrofolate reductase.
    Ercikan E; Waltham M; Dicker A; Schweitzer B; Bertino JR
    Adv Exp Med Biol; 1993; 338():515-9. PubMed ID: 8304170
    [No Abstract]   [Full Text] [Related]  

  • 6. Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.
    Senkovich O; Schormann N; Chattopadhyay D
    Acta Crystallogr D Biol Crystallogr; 2009 Jul; 65(Pt 7):704-16. PubMed ID: 19564691
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Correlations of inhibitor kinetics for Pneumocystis jirovecii and human dihydrofolate reductase with structural data for human active site mutant enzyme complexes.
    Cody V; Pace J; Makin J; Piraino J; Queener SF; Rosowsky A
    Biochemistry; 2009 Mar; 48(8):1702-11. PubMed ID: 19196009
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nonadditivity of mutational effects at the folate binding site of Escherichia coli dihydrofolate reductase.
    Huang Z; Wagner CR; Benkovic SJ
    Biochemistry; 1994 Sep; 33(38):11576-85. PubMed ID: 7918371
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment.
    Skacel N; Menon LG; Mishra PJ; Peters R; Banerjee D; Bertino JR; Abali EE
    J Biol Chem; 2005 Jun; 280(24):22721-31. PubMed ID: 15817466
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The tail wagging the dog: insights into catalysis in R67 dihydrofolate reductase.
    Kamath G; Howell EE; Agarwal PK
    Biochemistry; 2010 Oct; 49(42):9078-88. PubMed ID: 20795731
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Site-directed mutagenesis of mouse dihydrofolate reductase. Mutants with increased resistance to methotrexate and trimethoprim.
    Thillet J; Absil J; Stone SR; Pictet R
    J Biol Chem; 1988 Sep; 263(25):12500-8. PubMed ID: 3045118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The coordination of the isomerization of a conserved non-prolyl cis peptide bond with the rate-limiting steps in the folding of dihydrofolate reductase.
    Svensson AK; O'Neill JC; Matthews CR
    J Mol Biol; 2003 Feb; 326(2):569-83. PubMed ID: 12559923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of ionic interactions in ligand binding and catalysis of R67 dihydrofolate reductase.
    Hicks SN; Smiley RD; Hamilton JB; Howell EE
    Biochemistry; 2003 Sep; 42(36):10569-78. PubMed ID: 12962480
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
    McIvor RS
    Bone Marrow Transplant; 1996 Dec; 18 Suppl 3():S50-4. PubMed ID: 8971409
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Methotrexate resistance of mouse dihydrofolate reductase: effect of substitution of phenylalanine-31 by serine or tryptophan.
    Evenson DA; Adams J; McIvor RS; Wagner CR
    J Med Chem; 1996 Apr; 39(9):1763-6. PubMed ID: 8627598
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The crystal structure of dihydrofolate reductase from Thermotoga maritima: molecular features of thermostability.
    Dams T; Auerbach G; Bader G; Jacob U; Ploom T; Huber R; Jaenicke R
    J Mol Biol; 2000 Mar; 297(3):659-72. PubMed ID: 10731419
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Complementation between dimeric mutants as a probe of dimer-dimer interactions in tetrameric dihydrofolate reductase encoded by R67 plasmid of E. coli.
    Dam J; Rose T; Goldberg ME; Blondel A
    J Mol Biol; 2000 Sep; 302(1):235-50. PubMed ID: 10964572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.
    Affleck JG; Al-Batayneh KM; Neumann K; Cole SP; Walker VK
    Eur J Pharmacol; 2006 Jan; 529(1-3):71-8. PubMed ID: 16325803
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Screening of protein-ligand interactions under crude conditions by native mass spectrometry.
    Takano K; Arai S; Sakamoto S; Ushijima H; Ikegami T; Saikusa K; Konuma T; Hamachi I; Akashi S
    Anal Bioanal Chem; 2020 Jul; 412(17):4037-4043. PubMed ID: 32328689
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tobacco budworm dihydrofolate reductase is a promising target for insecticide discovery.
    Walker VK; Tyshenko MG; Kuiper MJ; Dargar RV; Yuhas DA; Cruickshank PA; Chaguturu R
    Eur J Biochem; 2000 Jan; 267(2):394-403. PubMed ID: 10632709
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.