BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

333 related articles for article (PubMed ID: 22733759)

  • 1. Phosphoinositide isoforms determine compartment-specific ion channel activity.
    Zhang X; Li X; Xu H
    Proc Natl Acad Sci U S A; 2012 Jul; 109(28):11384-9. PubMed ID: 22733759
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drosophila TRPML forms PI(3,5)P2-activated cation channels in both endolysosomes and plasma membrane.
    Feng X; Huang Y; Lu Y; Xiong J; Wong CO; Yang P; Xia J; Chen D; Du G; Venkatachalam K; Xia X; Zhu MX
    J Biol Chem; 2014 Feb; 289(7):4262-72. PubMed ID: 24375408
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome.
    Dong XP; Shen D; Wang X; Dawson T; Li X; Zhang Q; Cheng X; Zhang Y; Weisman LS; Delling M; Xu H
    Nat Commun; 2010 Jul; 1(4):38. PubMed ID: 20802798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides.
    Borbiro I; Badheka D; Rohacs T
    Sci Signal; 2015 Feb; 8(363):ra15. PubMed ID: 25670203
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A TRP channel in the lysosome regulates large particle phagocytosis via focal exocytosis.
    Samie M; Wang X; Zhang X; Goschka A; Li X; Cheng X; Gregg E; Azar M; Zhuo Y; Garrity AG; Gao Q; Slaugenhaupt S; Pickel J; Zolov SN; Weisman LS; Lenk GM; Titus S; Bryant-Genevier M; Southall N; Juan M; Ferrer M; Xu H
    Dev Cell; 2013 Sep; 26(5):511-24. PubMed ID: 23993788
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The lysosomal Ca
    Cao Q; Yang Y; Zhong XZ; Dong XP
    J Biol Chem; 2017 May; 292(20):8424-8435. PubMed ID: 28360104
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transient receptor potential melastatin 3 is a phosphoinositide-dependent ion channel.
    Badheka D; Borbiro I; Rohacs T
    J Gen Physiol; 2015 Jul; 146(1):65-77. PubMed ID: 26123195
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism.
    Zhang S; Li N; Zeng W; Gao N; Yang M
    Protein Cell; 2017 Nov; 8(11):834-847. PubMed ID: 28936784
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis.
    Dong XP; Wang X; Shen D; Chen S; Liu M; Wang Y; Mills E; Cheng X; Delling M; Xu H
    J Biol Chem; 2009 Nov; 284(46):32040-52. PubMed ID: 19638346
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Phosphoinositide-Gated Lysosomal Ca(2+) Channel, TRPML1, Is Required for Phagosome Maturation.
    Dayam RM; Saric A; Shilliday RE; Botelho RJ
    Traffic; 2015 Sep; 16(9):1010-26. PubMed ID: 26010303
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides.
    Korzeniowski MK; Popovic MA; Szentpetery Z; Varnai P; Stojilkovic SS; Balla T
    J Biol Chem; 2009 Jul; 284(31):21027-35. PubMed ID: 19483082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel.
    Dong XP; Cheng X; Mills E; Delling M; Wang F; Kurz T; Xu H
    Nature; 2008 Oct; 455(7215):992-6. PubMed ID: 18794901
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation.
    Li X; Rydzewski N; Hider A; Zhang X; Yang J; Wang W; Gao Q; Cheng X; Xu H
    Nat Cell Biol; 2016 Apr; 18(4):404-17. PubMed ID: 26950892
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR.
    Zhang X; Chen W; Gao Q; Yang J; Yan X; Zhao H; Su L; Yang M; Gao C; Yao Y; Inoki K; Li D; Shao R; Wang S; Sahoo N; Kudo F; Eguchi T; Ruan B; Xu H
    PLoS Biol; 2019 May; 17(5):e3000252. PubMed ID: 31112550
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics.
    Li X; Wang X; Zhang X; Zhao M; Tsang WL; Zhang Y; Yau RG; Weisman LS; Xu H
    Proc Natl Acad Sci U S A; 2013 Dec; 110(52):21165-70. PubMed ID: 24324172
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lysosomal Ca
    Yang Y; Xu M; Zhu X; Yao J; Shen B; Dong XP
    Eur J Cell Biol; 2019 Jun; 98(2-4):116-123. PubMed ID: 31122790
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential mechanisms of action of the mucolipin synthetic agonist, ML-SA1, on insect TRPML and mammalian TRPML1.
    Feng X; Xiong J; Lu Y; Xia X; Zhu MX
    Cell Calcium; 2014 Dec; 56(6):446-56. PubMed ID: 25266962
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P
    Gan N; Han Y; Zeng W; Wang Y; Xue J; Jiang Y
    Proc Natl Acad Sci U S A; 2022 Feb; 119(7):. PubMed ID: 35131932
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fusion of lysosomes with secretory organelles leads to uncontrolled exocytosis in the lysosomal storage disease mucolipidosis type IV.
    Park S; Ahuja M; Kim MS; Brailoiu GC; Jha A; Zeng M; Baydyuk M; Wu LG; Wassif CA; Porter FD; Zerfas PM; Eckhaus MA; Brailoiu E; Shin DM; Muallem S
    EMBO Rep; 2016 Feb; 17(2):266-78. PubMed ID: 26682800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release.
    Shen D; Wang X; Li X; Zhang X; Yao Z; Dibble S; Dong XP; Yu T; Lieberman AP; Showalter HD; Xu H
    Nat Commun; 2012 Mar; 3():731. PubMed ID: 22415822
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.