BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 22733822)

  • 1. Ring finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damage.
    Chen J; Feng W; Jiang J; Deng Y; Huen MS
    J Biol Chem; 2012 Aug; 287(33):27715-22. PubMed ID: 22733822
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks.
    Poulsen M; Lukas C; Lukas J; Bekker-Jensen S; Mailand N
    J Cell Biol; 2012 Apr; 197(2):189-99. PubMed ID: 22492721
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases.
    Mosbech A; Lukas C; Bekker-Jensen S; Mailand N
    J Biol Chem; 2013 Jun; 288(23):16579-16587. PubMed ID: 23615962
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.
    Thorslund T; Ripplinger A; Hoffmann S; Wild T; Uckelmann M; Villumsen B; Narita T; Sixma TK; Choudhary C; Bekker-Jensen S; Mailand N
    Nature; 2015 Nov; 527(7578):389-93. PubMed ID: 26503038
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18.
    Hu Q; Botuyan MV; Cui G; Zhao D; Mer G
    Mol Cell; 2017 May; 66(4):473-487.e9. PubMed ID: 28506460
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNF126 Quenches RNF168 Function in the DNA Damage Response.
    Zhang L; Wang Z; Shi R; Zhu X; Zhou J; Peng B; Xu X
    Genomics Proteomics Bioinformatics; 2018 Dec; 16(6):428-438. PubMed ID: 30529286
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks.
    Panier S; Ichijima Y; Fradet-Turcotte A; Leung CC; Kaustov L; Arrowsmith CH; Durocher D
    Mol Cell; 2012 Aug; 47(3):383-95. PubMed ID: 22742833
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events.
    Giunta S; Jackson SP
    Cell Cycle; 2011 Apr; 10(8):1215-21. PubMed ID: 21412056
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells.
    Oestergaard VH; Pentzold C; Pedersen RT; Iosif S; Alpi A; Bekker-Jensen S; Mailand N; Lisby M
    DNA Repair (Amst); 2012 Nov; 11(11):892-905. PubMed ID: 23010445
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks.
    Bekker-Jensen S; Mailand N
    FEBS Lett; 2011 Sep; 585(18):2914-9. PubMed ID: 21664912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks.
    Sy SM; Jiang J; O WS; Deng Y; Huen MS
    Nucleic Acids Res; 2013 Oct; 41(18):8572-80. PubMed ID: 23863847
    [TBL] [Abstract][Full Text] [Related]  

  • 12. L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage.
    Nowsheen S; Aziz K; Aziz A; Deng M; Qin B; Luo K; Jeganathan KB; Zhang H; Liu T; Yu J; Deng Y; Yuan J; Ding W; van Deursen JM; Lou Z
    Nat Cell Biol; 2018 Apr; 20(4):455-464. PubMed ID: 29581593
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNF8-independent Lys63 poly-ubiquitylation prevents genomic instability in response to replication-associated DNA damage.
    Ramaekers CH; van den Beucken T; Bristow RG; Chiu RK; Durocher D; Wouters BG
    PLoS One; 2014; 9(2):e89997. PubMed ID: 24587176
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168.
    KocyƂowski MK; Rey AJ; Stewart GS; Halazonetis TD
    Cell Cycle; 2015; 14(11):1748-58. PubMed ID: 25695757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNF169 limits 53BP1 deposition at DSBs to stimulate single-strand annealing repair.
    An L; Dong C; Li J; Chen J; Yuan J; Huang J; Chan KM; Yu CH; Huen MSY
    Proc Natl Acad Sci U S A; 2018 Aug; 115(35):E8286-E8295. PubMed ID: 30104380
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice.
    Nakada S
    J Radiat Res; 2016 Aug; 57 Suppl 1(Suppl 1):i33-i40. PubMed ID: 26983989
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.
    Doil C; Mailand N; Bekker-Jensen S; Menard P; Larsen DH; Pepperkok R; Ellenberg J; Panier S; Durocher D; Bartek J; Lukas J; Lukas C
    Cell; 2009 Feb; 136(3):435-46. PubMed ID: 19203579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response.
    Walser F; Mulder MPC; Bragantini B; Burger S; Gubser T; Gatti M; Botuyan MV; Villa A; Altmeyer M; Neri D; Ovaa H; Mer G; Penengo L
    Mol Cell; 2020 Nov; 80(3):423-436.e9. PubMed ID: 33022275
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dual-utility NLS drives RNF169-dependent DNA damage responses.
    An L; Jiang Y; Ng HH; Man EP; Chen J; Khoo US; Gong Q; Huen MS
    Proc Natl Acad Sci U S A; 2017 Apr; 114(14):E2872-E2881. PubMed ID: 28325877
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.
    Galanty Y; Belotserkovskaya R; Coates J; Polo S; Miller KM; Jackson SP
    Nature; 2009 Dec; 462(7275):935-9. PubMed ID: 20016603
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.