These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 22735906)

  • 1. Phase I study of TAS-102 treatment in Japanese patients with advanced solid tumours.
    Doi T; Ohtsu A; Yoshino T; Boku N; Onozawa Y; Fukutomi A; Hironaka S; Koizumi W; Sasaki T
    Br J Cancer; 2012 Jul; 107(3):429-34. PubMed ID: 22735906
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phase 1 study of TAS-102 administered once daily on a 5-day-per-week schedule in patients with solid tumors.
    Overman MJ; Varadhachary G; Kopetz S; Thomas MB; Fukushima M; Kuwata K; Mita A; Wolff RA; Hoff PM; Xiong H; Abbruzzese JL
    Invest New Drugs; 2008 Oct; 26(5):445-54. PubMed ID: 18528634
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Phase I dose-escalation study of third-line regorafenib with trifluridine/tipiracil in metastatic colorectal cancer.
    Moehler M; Michel M; Stein A; Trojan J; Marquardt J; Tintelnot J; Waidmann O; Weinmann A; Woerns MA; Schroeder H; Maenz M; Foerster F
    Future Oncol; 2021 Sep; 17(25):3309-3319. PubMed ID: 33993741
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phase I study of trifluridine/tipiracil (TAS-102) plus irinotecan in combination with bevacizumab as a second-line therapy for patients with metastatic colorectal cancer.
    Zhang J; Yang W; Liu J; Wang N; Ren Z; Yang T; Xie G; Wu G; Sun Y
    Invest New Drugs; 2024 Aug; 42(4):454-461. PubMed ID: 38990451
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phase I dose-escalation of trifluridine/tipiracil in combination with oxaliplatin in patients with metastatic colorectal cancer.
    Argilés G; André T; Hollebecque A; Calvo A; Dahan L; Cervantes A; Leger C; Amellal N; Fougeray R; Tabernero J
    Eur J Cancer; 2019 May; 112():12-19. PubMed ID: 30889492
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Open-label study to evaluate trifluridine/tipiracil safety, tolerability and pharmacokinetics in patients with advanced solid tumours and hepatic impairment.
    Saif MW; Rosen L; Rudek MA; Sun W; Shepard DR; Becerra C; Yamashita F; Bebeau P; Winkler R
    Br J Clin Pharmacol; 2019 Jun; 85(6):1239-1246. PubMed ID: 30628113
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A multicenter phase II study of TAS-102 monotherapy in patients with pre-treated advanced gastric cancer (EPOC1201).
    Bando H; Doi T; Muro K; Yasui H; Nishina T; Yamaguchi K; Takahashi S; Nomura S; Kuno H; Shitara K; Sato A; Ohtsu A
    Eur J Cancer; 2016 Jul; 62():46-53. PubMed ID: 27208903
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A phase 1b expansion study of TAS-102 with oxaliplatin for refractory metastatic colorectal cancer.
    Cecchini M; Kortmansky JS; Cui C; Wei W; Thumar JR; Uboha NV; Hafez N; Lacy J; Fischbach NA; Sabbath KD; Gomez CM; Sporn JR; Stein S; Hochster HS
    Cancer; 2021 May; 127(9):1417-1424. PubMed ID: 33351187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phase 1 dose escalation trial of TAS-102 (trifluridine/tipiracil) and temozolomide in the treatment of advanced neuroendocrine tumors.
    Uboha NV; Lubner SJ; LoConte NK; Mulkerin DL; Eickhoff JC; Deming DA
    Invest New Drugs; 2020 Oct; 38(5):1520-1525. PubMed ID: 32253554
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of food on the pharmacokinetics of TAS-102 and its efficacy and safety in patients with advanced solid tumors.
    Yoshino T; Kojima T; Bando H; Yamazaki T; Naito Y; Mukai H; Fuse N; Goto K; Ito Y; Doi T; Ohtsu A
    Cancer Sci; 2016 May; 107(5):659-65. PubMed ID: 26918279
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Phase 1, Open-Label, Randomized, Crossover Study Evaluating the Bioavailability of TAS-102 (Trifluridine/Tipiracil) Tablets Relative to an Oral Solution Containing Equivalent Amounts of Trifluridine and Tipiracil.
    Becerra CR; Yoshida K; Mizuguchi H; Patel M; Von Hoff D
    J Clin Pharmacol; 2017 Jun; 57(6):751-759. PubMed ID: 28070894
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phase I study of TAS-102 and irinotecan combination therapy in Japanese patients with advanced colorectal cancer.
    Doi T; Yoshino T; Fuse N; Boku N; Yamazaki K; Koizumi W; Shimada K; Takinishi Y; Ohtsu A
    Invest New Drugs; 2015 Oct; 33(5):1068-77. PubMed ID: 26163340
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phase I study to determine the safety and pharmacokinetics of oral administration of TAS-102 in patients with solid tumors.
    Hong DS; Abbruzzese JL; Bogaard K; Lassere Y; Fukushima M; Mita A; Kuwata K; Hoff PM
    Cancer; 2006 Sep; 107(6):1383-90. PubMed ID: 16902987
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A phase I, open-label study evaluating the safety and pharmacokinetics of trifluridine/tipiracil in patients with advanced solid tumors and varying degrees of renal impairment.
    Saif MW; Becerra CR; Fakih MG; Sun W; Popovic L; Krishnamurthi S; George TJ; Rudek MA; Shepard DR; Skopek J; Sramek V; Zaric B; Yamamiya I; Benhadji KA; Hamada K; He Y; Rosen L
    Cancer Chemother Pharmacol; 2021 Sep; 88(3):485-497. PubMed ID: 34097100
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phase I clinical study of three times a day oral administration of TAS-102 in patients with solid tumors.
    Overman MJ; Kopetz S; Varadhachary G; Fukushima M; Kuwata K; Mita A; Wolff RA; Hoff P; Xiong H; Abbruzzese JL
    Cancer Invest; 2008 Oct; 26(8):794-9. PubMed ID: 18798063
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adherence, Dosing, and Managing Toxicities With Trifluridine/Tipiracil (TAS-102).
    Lee JJ; Chu E
    Clin Colorectal Cancer; 2017 Jun; 16(2):85-92. PubMed ID: 28242161
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A phase 1 study of the pharmacokinetics of nucleoside analog trifluridine and thymidine phosphorylase inhibitor tipiracil (components of TAS-102) vs trifluridine alone.
    Cleary JM; Rosen LS; Yoshida K; Rasco D; Shapiro GI; Sun W
    Invest New Drugs; 2017 Apr; 35(2):189-197. PubMed ID: 28111727
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors.
    Bendell JC; Patel MR; Yoshida K; Seraj J; Weaver R; Lemech C; Todaro TG; Pant S; Arkenau HT
    Cancer Chemother Pharmacol; 2016 Jun; 77(6):1275-83. PubMed ID: 27151157
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer.
    Bendell JC; Rosen LS; Mayer RJ; Goldman JW; Infante JR; Benedetti F; Lin D; Mizuguchi H; Zergebel C; Patel MR
    Cancer Chemother Pharmacol; 2015 Nov; 76(5):925-32. PubMed ID: 26370544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phase II study of trifluridine/tipiracil (TAS-102) therapy in elderly patients with colorectal cancer (T-CORE1401): geriatric assessment tools and plasma drug concentrations as possible predictive biomarkers.
    Takahashi M; Sakamoto Y; Ohori H; Tsuji Y; Kuroki M; Kato S; Otsuka K; Komine K; Takahashi M; Takahashi S; Shirota H; Ouchi K; Takahashi Y; Imai H; Shibata H; Yoshioka T; Tanaka M; Yamaguchi H; Yamaguchi T; Shimodaira H; Ishioka C
    Cancer Chemother Pharmacol; 2021 Sep; 88(3):393-402. PubMed ID: 34028598
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.