119 related articles for article (PubMed ID: 22738631)
1. New farnesyltransferase inhibitors in the phenothiazine series.
Belei D; Dumea C; Samson A; Farce A; Dubois J; Bîcu E; Ghinet A
Bioorg Med Chem Lett; 2012 Jul; 22(14):4517-22. PubMed ID: 22738631
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of new phenothiazine derivatives bearing a pyrazole unit as protein farnesyltransferase inhibitors.
Baciu-Atudosie L; Ghinet A; Farce A; Dubois J; Belei D; Bîcu E
Bioorg Med Chem Lett; 2012 Nov; 22(22):6896-902. PubMed ID: 23036952
[TBL] [Abstract][Full Text] [Related]
3. Peptide chemistry applied to a new family of phenothiazine-containing inhibitors of human farnesyltransferase.
Dumitriu GM; Ghinet A; Bîcu E; Rigo B; Dubois J; Farce A; Belei D
Bioorg Med Chem Lett; 2014 Jul; 24(14):3180-5. PubMed ID: 24856060
[TBL] [Abstract][Full Text] [Related]
4. Indolizine-phenothiazine hybrids as the first dual inhibitors of tubulin polymerization and farnesyltransferase with synergistic antitumor activity.
Moise IM; Bîcu E; Farce A; Dubois J; Ghinet A
Bioorg Chem; 2020 Oct; 103():104184. PubMed ID: 32891861
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of a new series of phenothiazine-containing protein farnesyltransferase inhibitors.
Abuhaie CM; Ghinet A; Farce A; Dubois J; Gautret P; Rigo B; Belei D; Bîcu E
Eur J Med Chem; 2013 Jan; 59():101-10. PubMed ID: 23207411
[TBL] [Abstract][Full Text] [Related]
6. Phenothiazine-based CaaX competitive inhibitors of human farnesyltransferase bearing a cysteine, methionine, serine or valine moiety as a new family of antitumoral compounds.
Dumitriu GM; Bîcu E; Belei D; Rigo B; Dubois J; Farce A; Ghinet A
Bioorg Med Chem Lett; 2015 Oct; 25(20):4447-52. PubMed ID: 26372651
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of a new series of N-ylides as protein farnesyltransferase inhibitors.
Abuhaie CM; Ghinet A; Farce A; Dubois J; Rigo B; Bîcu E
Bioorg Med Chem Lett; 2013 Nov; 23(21):5887-92. PubMed ID: 24054122
[TBL] [Abstract][Full Text] [Related]
8. Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.
Wlodarczyk N; Le Broc-Ryckewaert D; Gilleron P; Lemoine A; Farce A; Chavatte P; Dubois J; Pommery N; Hénichart JP; Furman C; Millet R
J Med Chem; 2011 Mar; 54(5):1178-90. PubMed ID: 21299244
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of imidazole-containing analogues of farnesyl pyrophosphate and evaluation of their biological activity on protein farnesyltransferase.
Coudray L; de Figueiredo RM; Duez S; Cortial S; Dubois J
J Enzyme Inhib Med Chem; 2009 Aug; 24(4):972-85. PubMed ID: 19555171
[TBL] [Abstract][Full Text] [Related]
10. Non-thiol farnesyltransferase inhibitors: FTase-inhibition and cellular activity of benzophenone-based bisubstrate analogue farnesyltransferase inhibitors.
Mitsch A; Bergemann S; Gust R; Sattler I; Schlitzer M
Arch Pharm (Weinheim); 2003 Jul; 336(4-5):242-50. PubMed ID: 12916059
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and characterization of piperazinedione-based dual protein inhibitors for both farnesyltransferase and geranylgeranyltransferase-I.
Qiao Y; Gao J; Qiu Y; Wu L; Guo F; Lo KK; Li D
Eur J Med Chem; 2011 Jun; 46(6):2264-73. PubMed ID: 21440964
[TBL] [Abstract][Full Text] [Related]
12. New indolizine-chalcones as potent inhibitors of human farnesyltransferase: Design, synthesis and biological evaluation.
Moise IM; Ghinet A; Belei D; Dubois J; Farce A; Bîcu E
Bioorg Med Chem Lett; 2016 Aug; 26(15):3730-4. PubMed ID: 27282741
[TBL] [Abstract][Full Text] [Related]
13. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Prinz H; Chamasmani B; Vogel K; Böhm KJ; Aicher B; Gerlach M; Günther EG; Amon P; Ivanov I; Müller K
J Med Chem; 2011 Jun; 54(12):4247-63. PubMed ID: 21563750
[TBL] [Abstract][Full Text] [Related]
14. Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues.
Duez S; Coudray L; Mouray E; Grellier P; Dubois J
Bioorg Med Chem; 2010 Jan; 18(2):543-56. PubMed ID: 20036564
[TBL] [Abstract][Full Text] [Related]
15. Computer-aided drug design and ADMET predictions for identification and evaluation of novel potential farnesyltransferase inhibitors in cancer therapy.
da Silva CH; da Silva VB; Resende J; Rodrigues PF; Bononi FC; Benevenuto CG; Taft CA
J Mol Graph Model; 2010 Feb; 28(6):513-23. PubMed ID: 20074987
[TBL] [Abstract][Full Text] [Related]
16. Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors.
Cadelis MM; Bourguet-Kondracki ML; Dubois J; Valentin A; Barker D; Copp BR
Bioorg Med Chem; 2016 Jul; 24(14):3102-7. PubMed ID: 27240468
[TBL] [Abstract][Full Text] [Related]
17. 3D-QSAR with the aid of pharmacophore search and docking-based alignments for farnesyltransferase inhibitors.
Vaidya M; Weigt M; Wiese M
Eur J Med Chem; 2009 Oct; 44(10):4070-82. PubMed ID: 19515462
[TBL] [Abstract][Full Text] [Related]
18. Antitumor activity of phenothiazine-related compounds.
Nagy S; Argyelan G; Molnár J; Kawase M; Motohashi N
Anticancer Res; 1996; 16(4A):1915-8. PubMed ID: 8712720
[TBL] [Abstract][Full Text] [Related]
19. Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase.
Nara S; Tanaka R; Eishima J; Hara M; Takahashi Y; Otaki S; Foglesong RJ; Hughes PF; Turkington S; Kanda Y
J Med Chem; 2003 Jun; 46(12):2467-73. PubMed ID: 12773050
[TBL] [Abstract][Full Text] [Related]
20. Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency.
Bolchi C; Pallavicini M; Rusconi C; Diomede L; Ferri N; Corsini A; Fumagalli L; Pedretti A; Vistoli G; Valoti E
Bioorg Med Chem Lett; 2007 Nov; 17(22):6192-6. PubMed ID: 17889533
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
