199 related articles for article (PubMed ID: 22740703)
1. The in silico screening and X-ray structure analysis of the inhibitor complex of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase.
Takashima Y; Mizohata E; Krungkrai SR; Fukunishi Y; Kinoshita T; Sakata T; Matsumura H; Krungkrai J; Horii T; Inoue T
J Biochem; 2012 Aug; 152(2):133-8. PubMed ID: 22740703
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for the decarboxylation of orotidine 5'-monophosphate (OMP) by Plasmodium falciparum OMP decarboxylase.
Tokuoka K; Kusakari Y; Krungkrai SR; Matsumura H; Kai Y; Krungkrai J; Horii T; Inoue T
J Biochem; 2008 Jan; 143(1):69-78. PubMed ID: 17981823
[TBL] [Abstract][Full Text] [Related]
3. A novel enzyme complex of orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase in human malaria parasite Plasmodium falciparum: physical association, kinetics, and inhibition characterization.
Krungkrai SR; DelFraino BJ; Smiley JA; Prapunwattana P; Mitamura T; Horii T; Krungkrai J
Biochemistry; 2005 Feb; 44(5):1643-52. PubMed ID: 15683248
[TBL] [Abstract][Full Text] [Related]
4. A potent, covalent inhibitor of orotidine 5'-monophosphate decarboxylase with antimalarial activity.
Bello AM; Poduch E; Fujihashi M; Amani M; Li Y; Crandall I; Hui R; Lee PI; Kain KC; Pai EF; Kotra LP
J Med Chem; 2007 Mar; 50(5):915-21. PubMed ID: 17290979
[TBL] [Abstract][Full Text] [Related]
5. Structure and inhibition of orotidine 5'-monophosphate decarboxylase from Plasmodium falciparum.
Langley DB; Shojaei M; Chan C; Lok HC; Mackay JP; Traut TW; Guss JM; Christopherson RI
Biochemistry; 2008 Mar; 47(12):3842-54. PubMed ID: 18303855
[TBL] [Abstract][Full Text] [Related]
6. Re-refinement of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase provides a clearer picture of an important malarial drug target.
Novak WRP; West KHJ; Kirkman LMD; Brandt GS
Acta Crystallogr F Struct Biol Commun; 2018 Oct; 74(Pt 10):664-668. PubMed ID: 30279319
[TBL] [Abstract][Full Text] [Related]
7. Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase.
Bello AM; Poduch E; Liu Y; Wei L; Crandall I; Wang X; Dyanand C; Kain KC; Pai EF; Kotra LP
J Med Chem; 2008 Feb; 51(3):439-48. PubMed ID: 18189347
[TBL] [Abstract][Full Text] [Related]
8. Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.
Purohit MK; Poduch E; Wei LW; Crandall IE; To T; Kain KC; Pai EF; Kotra LP
J Med Chem; 2012 Nov; 55(22):9988-97. PubMed ID: 22991951
[TBL] [Abstract][Full Text] [Related]
9. Substrate binding induces domain movements in orotidine 5'-monophosphate decarboxylase.
Harris P; Poulsen JC; Jensen KF; Larsen S
J Mol Biol; 2002 May; 318(4):1019-29. PubMed ID: 12054799
[TBL] [Abstract][Full Text] [Related]
10. Design of inhibitors of orotidine monophosphate decarboxylase using bioisosteric replacement and determination of inhibition kinetics.
Poduch E; Bello AM; Tang S; Fujihashi M; Pai EF; Kotra LP
J Med Chem; 2006 Aug; 49(16):4937-45. PubMed ID: 16884305
[TBL] [Abstract][Full Text] [Related]
11. Crystallization and preliminary crystallographic analysis of orotidine 5'-monophosphate decarboxylase from the human malaria parasite Plasmodium falciparum.
Krungkrai SR; Tokuoka K; Kusakari Y; Inoue T; Adachi H; Matsumura H; Takano K; Murakami S; Mori Y; Kai Y; Krungkrai J; Horii T
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2006 Jun; 62(Pt 6):542-5. PubMed ID: 16754976
[TBL] [Abstract][Full Text] [Related]
12. Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase.
Wu N; Pai EF
J Biol Chem; 2002 Aug; 277(31):28080-7. PubMed ID: 12011084
[TBL] [Abstract][Full Text] [Related]
13. Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase.
Heinrich D; Diederichsen U; Rudolph MG
Chemistry; 2009 Jul; 15(27):6619-25. PubMed ID: 19472232
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of orotidine-5'-monophosphate decarboxylase--discoveries and lessons.
Kotra LP; Pai EF
Nucleic Acids Symp Ser (Oxf); 2008; (52):85-6. PubMed ID: 18776265
[TBL] [Abstract][Full Text] [Related]
15. Orotidine Monophosphate Decarboxylase--A Fascinating Workhorse Enzyme with Therapeutic Potential.
Fujihashi M; Mnpotra JS; Mishra RK; Pai EF; Kotra LP
J Genet Genomics; 2015 May; 42(5):221-34. PubMed ID: 26059770
[TBL] [Abstract][Full Text] [Related]
16. Structural basis for the catalytic mechanism of a proficient enzyme: orotidine 5'-monophosphate decarboxylase.
Harris P; Navarro Poulsen JC; Jensen KF; Larsen S
Biochemistry; 2000 Apr; 39(15):4217-24. PubMed ID: 10757968
[TBL] [Abstract][Full Text] [Related]
17. Orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum.
Krungkrai SR; Prapunwattana P; Horii T; Krungkrai J
Biochem Biophys Res Commun; 2004 Jun; 318(4):1012-8. PubMed ID: 15147974
[TBL] [Abstract][Full Text] [Related]
18. Pseudo-merohedral twinning in monoclinic crystals of human orotidine-5'-monophosphate decarboxylase.
Wittmann JG; Rudolph MG
Acta Crystallogr D Biol Crystallogr; 2007 Jun; 63(Pt 6):744-9. PubMed ID: 17505114
[TBL] [Abstract][Full Text] [Related]
19. Structural diversity and plasticity associated with nucleotides targeting orotidine monophosphate decarboxylase.
Poduch E; Wei L; Pai EF; Kotra LP
J Med Chem; 2008 Feb; 51(3):432-8. PubMed ID: 18181562
[TBL] [Abstract][Full Text] [Related]
20. Chemical models and their mechanistic implications for the transformation of 6-cyanouridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase.
Wu YJ; Liao CC; Jen CH; Shih YC; Chien TC
Chem Commun (Camb); 2010 Jul; 46(26):4821-3. PubMed ID: 20498911
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
