BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 22743999)

  • 1. Cyclin-dependent kinases 7 and 9 specifically regulate neutrophil transcription and their inhibition drives apoptosis to promote resolution of inflammation.
    Leitch AE; Lucas CD; Marwick JA; Duffin R; Haslett C; Rossi AG
    Cell Death Differ; 2012 Dec; 19(12):1950-61. PubMed ID: 22743999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis.
    Wang K; Hampson P; Hazeldine J; Krystof V; Strnad M; Pechan P; M J
    PLoS One; 2012; 7(1):e30128. PubMed ID: 22276149
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the cyclin-dependent kinases at the beginning of human cytomegalovirus infection specifically alters the levels and localization of the RNA polymerase II carboxyl-terminal domain kinases cdk9 and cdk7 at the viral transcriptosome.
    Kapasi AJ; Spector DH
    J Virol; 2008 Jan; 82(1):394-407. PubMed ID: 17942543
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cyclin-dependent kinase inhibitor R-roscovitine down-regulates Mcl-1 to override pro-inflammatory signalling and drive neutrophil apoptosis.
    Leitch AE; Riley NA; Sheldrake TA; Festa M; Fox S; Duffin R; Haslett C; Rossi AG
    Eur J Immunol; 2010 Apr; 40(4):1127-38. PubMed ID: 20127676
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Xylocydine, a novel Cdk inhibitor, is an effective inducer of apoptosis in hepatocellular carcinoma cells in vitro and in vivo.
    Cho SJ; Lee SS; Kim YJ; Park BD; Choi JS; Liu L; Ham YM; Moon Kim B; Lee SK
    Cancer Lett; 2010 Jan; 287(2):196-206. PubMed ID: 19616371
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of the cyclin-dependent kinase inhibitor R-roscovitine on eosinophil survival and clearance.
    Farahi N; Uller L; Juss JK; Langton AJ; Cowburn AS; Gibson A; Foster MR; Farrow SN; Marco-Casanova P; Sobolewski A; Condliffe AM; Chilvers ER
    Clin Exp Allergy; 2011 May; 41(5):673-87. PubMed ID: 21255143
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia.
    Chen R; Wierda WG; Chubb S; Hawtin RE; Fox JA; Keating MJ; Gandhi V; Plunkett W
    Blood; 2009 May; 113(19):4637-45. PubMed ID: 19234140
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells.
    Kelso TW; Baumgart K; Eickhoff J; Albert T; Antrecht C; Lemcke S; Klebl B; Meisterernst M
    Mol Cell Biol; 2014 Oct; 34(19):3675-88. PubMed ID: 25047832
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of post-transcriptional RNA processing by CDK inhibitors and its implication in anti-viral therapy.
    Holcakova J; Muller P; Tomasec P; Hrstka R; Nekulova M; Krystof V; Strnad M; Wilkinson GW; Vojtesek B
    PLoS One; 2014; 9(2):e89228. PubMed ID: 24586613
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents.
    Leitch AE; Haslett C; Rossi AG
    Br J Pharmacol; 2009 Oct; 158(4):1004-16. PubMed ID: 19775281
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis.
    Rossi AG; Sawatzky DA; Walker A; Ward C; Sheldrake TA; Riley NA; Caldicott A; Martinez-Losa M; Walker TR; Duffin R; Gray M; Crescenzi E; Martin MC; Brady HJ; Savill JS; Dransfield I; Haslett C
    Nat Med; 2006 Sep; 12(9):1056-64. PubMed ID: 16951685
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roscovitine, olomoucine, purvalanol: inducers of apoptosis in maturing cerebellar granule neurons.
    Monaco EA; Beaman-Hall CM; Mathur A; Vallano ML
    Biochem Pharmacol; 2004 May; 67(10):1947-64. PubMed ID: 15130771
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Varicella-zoster virus IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity.
    Habran L; Bontems S; Di Valentin E; Sadzot-Delvaux C; Piette J
    J Biol Chem; 2005 Aug; 280(32):29135-43. PubMed ID: 15955820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel R-roscovitine NO-donor hybrid compounds as potential pro-resolution of inflammation agents.
    Montanaro G; Bertinaria M; Rolando B; Fruttero R; Lucas CD; Dorward DA; Rossi AG; Megson IL; Gasco A
    Bioorg Med Chem; 2013 Apr; 21(7):2107-16. PubMed ID: 23394865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roscovitine blocks leukocyte extravasation by inhibition of cyclin-dependent kinases 5 and 9.
    Berberich N; Uhl B; Joore J; Schmerwitz UK; Mayer BA; Reichel CA; Krombach F; Zahler S; Vollmar AM; Fürst R
    Br J Pharmacol; 2011 Jul; 163(5):1086-98. PubMed ID: 21391976
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heat-shock-specific phosphorylation and transcriptional activity of RNA polymerase II.
    Egyházi E; Ossoinak A; Lee JM; Greenleaf AL; Mäkelä TP; Pigon A
    Exp Cell Res; 1998 Jul; 242(1):211-21. PubMed ID: 9665818
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apoptosis of metastatic prostate cancer cells by a combination of cyclin-dependent kinase and AKT inhibitors.
    Mohapatra S; Chu B; Zhao X; Djeu J; Cheng JQ; Pledger WJ
    Int J Biochem Cell Biol; 2009 Mar; 41(3):595-602. PubMed ID: 18708158
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional role of RNA polymerase II and P70 S6 kinase in KCl withdrawal-induced cerebellar granule neuron apoptosis.
    Padmanabhan J; Brown KR; Padilla A; Shelanski ML
    J Biol Chem; 2015 Feb; 290(9):5267-79. PubMed ID: 25568312
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interference with ER-α enhances the therapeutic efficacy of the selective CDK inhibitor roscovitine towards ER-positive breast cancer cells.
    Węsierska-Gądek J; Gritsch D; Zulehner N; Komina O; Maurer M
    J Cell Biochem; 2011 Apr; 112(4):1103-17. PubMed ID: 21308739
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ibulocydine is a novel prodrug Cdk inhibitor that effectively induces apoptosis in hepatocellular carcinoma cells.
    Cho SJ; Kim YJ; Surh YJ; Kim BM; Lee SK
    J Biol Chem; 2011 Jun; 286(22):19662-71. PubMed ID: 21478145
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.