BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 22745126)

  • 1. DnaK chaperone-dependent disaggregation by caseinolytic peptidase B (ClpB) mutants reveals functional overlap in the N-terminal domain and nucleotide-binding domain-1 pore tyrosine.
    Doyle SM; Hoskins JR; Wickner S
    J Biol Chem; 2012 Aug; 287(34):28470-9. PubMed ID: 22745126
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interplay between E. coli DnaK, ClpB and GrpE during protein disaggregation.
    Doyle SM; Shastry S; Kravats AN; Shih YH; Miot M; Hoskins JR; Stan G; Wickner S
    J Mol Biol; 2015 Jan; 427(2):312-27. PubMed ID: 25451597
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation.
    Miot M; Reidy M; Doyle SM; Hoskins JR; Johnston DM; Genest O; Vitery MC; Masison DC; Wickner S
    Proc Natl Acad Sci U S A; 2011 Apr; 108(17):6915-20. PubMed ID: 21474779
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Coupling ATP utilization to protein remodeling by ClpB, a hexameric AAA+ protein.
    Hoskins JR; Doyle SM; Wickner S
    Proc Natl Acad Sci U S A; 2009 Dec; 106(52):22233-8. PubMed ID: 19940245
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ClpB N-terminal domain plays a regulatory role in protein disaggregation.
    Rosenzweig R; Farber P; Velyvis A; Rennella E; Latham MP; Kay LE
    Proc Natl Acad Sci U S A; 2015 Dec; 112(50):E6872-81. PubMed ID: 26621746
    [TBL] [Abstract][Full Text] [Related]  

  • 6. M domains couple the ClpB threading motor with the DnaK chaperone activity.
    Haslberger T; Weibezahn J; Zahn R; Lee S; Tsai FT; Bukau B; Mogk A
    Mol Cell; 2007 Jan; 25(2):247-60. PubMed ID: 17244532
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dissociation between the critical role of ClpB of Francisella tularensis for the heat shock response and the DnaK interaction and its important role for efficient type VI secretion and bacterial virulence.
    Alam A; Golovliov I; Javed E; Kumar R; Ådén J; Sjöstedt A
    PLoS Pathog; 2020 Apr; 16(4):e1008466. PubMed ID: 32275693
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation.
    Desantis ME; Sweeny EA; Snead D; Leung EH; Go MS; Gupta K; Wendler P; Shorter J
    J Biol Chem; 2014 Jan; 289(2):848-67. PubMed ID: 24280225
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fusion protein analysis reveals the precise regulation between Hsp70 and Hsp100 during protein disaggregation.
    Hayashi S; Nakazaki Y; Kagii K; Imamura H; Watanabe YH
    Sci Rep; 2017 Aug; 7(1):8648. PubMed ID: 28819163
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB.
    Weibezahn J; Tessarz P; Schlieker C; Zahn R; Maglica Z; Lee S; Zentgraf H; Weber-Ban EU; Dougan DA; Tsai FT; Mogk A; Bukau B
    Cell; 2004 Nov; 119(5):653-65. PubMed ID: 15550247
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a trap mutant of the AAA+ chaperone ClpB.
    Weibezahn J; Schlieker C; Bukau B; Mogk A
    J Biol Chem; 2003 Aug; 278(35):32608-17. PubMed ID: 12805357
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Escherichia coli DnaK Allosterically Modulates ClpB between High- and Low-Peptide Affinity States.
    Durie CL; Duran EC; Lucius AL
    Biochemistry; 2018 Jul; 57(26):3665-3675. PubMed ID: 29812913
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation.
    Mogk A; Deuerling E; Vorderwülbecke S; Vierling E; Bukau B
    Mol Microbiol; 2003 Oct; 50(2):585-95. PubMed ID: 14617181
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conserved amino acid residues within the amino-terminal domain of ClpB are essential for the chaperone activity.
    Liu Z; Tek V; Akoev V; Zolkiewski M
    J Mol Biol; 2002 Aug; 321(1):111-20. PubMed ID: 12139937
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repurposing p97 inhibitors for chemical modulation of the bacterial ClpB-DnaK bichaperone system.
    Glaza P; Ranaweera CB; Shiva S; Roy A; Geisbrecht BV; Schoenen FJ; Zolkiewski M
    J Biol Chem; 2021; 296():100079. PubMed ID: 33187983
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Flexible connection of the N-terminal domain in ClpB modulates substrate binding and the aggregate reactivation efficiency.
    Zhang T; Ploetz EA; Nagy M; Doyle SM; Wickner S; Smith PE; Zolkiewski M
    Proteins; 2012 Dec; 80(12):2758-68. PubMed ID: 22890624
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Roles of individual domains and conserved motifs of the AAA+ chaperone ClpB in oligomerization, ATP hydrolysis, and chaperone activity.
    Mogk A; Schlieker C; Strub C; Rist W; Weibezahn J; Bukau B
    J Biol Chem; 2003 May; 278(20):17615-24. PubMed ID: 12624113
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A chaperone network for the resolubilization of protein aggregates: direct interaction of ClpB and DnaK.
    Schlee S; Beinker P; Akhrymuk A; Reinstein J
    J Mol Biol; 2004 Feb; 336(1):275-85. PubMed ID: 14741222
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the DnaK-ClpB Complex is Regulated by the Properties of the Bound Substrate.
    Fernández-Higuero JA; Aguado A; Perales-Calvo J; Moro F; Muga A
    Sci Rep; 2018 Apr; 8(1):5796. PubMed ID: 29643454
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effect of co-overproduction of DnaK/DnaJ/GrpE and ClpB proteins on the removal of heat-aggregated proteins from Escherichia coli DeltaclpB mutant cells--new insight into the role of Hsp70 in a functional cooperation with Hsp100.
    Kedzierska S; Matuszewska E
    FEMS Microbiol Lett; 2001 Nov; 204(2):355-60. PubMed ID: 11731148
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.