These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients. Akhavan D; Pourzia AL; Nourian AA; Williams KJ; Nathanson D; Babic I; Villa GR; Tanaka K; Nael A; Yang H; Dang J; Vinters HV; Yong WH; Flagg M; Tamanoi F; Sasayama T; James CD; Kornblum HI; Cloughesy TF; Cavenee WK; Bensinger SJ; Mischel PS Cancer Discov; 2013 May; 3(5):534-47. PubMed ID: 23533263 [TBL] [Abstract][Full Text] [Related]
6. Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling. Dong M; Xiao Q; Hu J; Cheng F; Zhang P; Zong W; Tang Q; Li X; Mao F; He Y; Yu X; Wan F; Lei T; Guo D; Wang B Cancer Gene Ther; 2020 Dec; 27(12):878-897. PubMed ID: 31988476 [TBL] [Abstract][Full Text] [Related]
7. Differential role of EGF and BFGF in human GBM-TIC proliferation: relationship to EGFR-tyrosine kinase inhibitor sensibility. Bajetto A; Porcile C; Pattarozzi A; Scotti L; Aceto A; Daga A; Barbieri F; Florio T J Biol Regul Homeost Agents; 2013; 27(1):143-54. PubMed ID: 23489694 [TBL] [Abstract][Full Text] [Related]
8. A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem-Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy. Luraghi P; Bigatto V; Cipriano E; Reato G; Orzan F; Sassi F; De Bacco F; Isella C; Bellomo SE; Medico E; Comoglio PM; Bertotti A; Trusolino L; Boccaccio C Clin Cancer Res; 2018 Feb; 24(4):807-820. PubMed ID: 28974546 [No Abstract] [Full Text] [Related]
9. Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo. Signore M; Pelacchi F; di Martino S; Runci D; Biffoni M; Giannetti S; Morgante L; De Majo M; Petricoin EF; Stancato L; Larocca LM; De Maria R; Pallini R; Ricci-Vitiani L Cell Death Dis; 2014 May; 5(5):e1223. PubMed ID: 24810059 [TBL] [Abstract][Full Text] [Related]
10. Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies. Cho J; Pastorino S; Zeng Q; Xu X; Johnson W; Vandenberg S; Verhaak R; Cherniack AD; Watanabe H; Dutt A; Kwon J; Chao YS; Onofrio RC; Chiang D; Yuza Y; Kesari S; Meyerson M Cancer Res; 2011 Dec; 71(24):7587-96. PubMed ID: 22001862 [TBL] [Abstract][Full Text] [Related]
11. Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells. Hu J; Jo M; Cavenee WK; Furnari F; VandenBerg SR; Gonias SL Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15984-9. PubMed ID: 21896743 [TBL] [Abstract][Full Text] [Related]
12. EGFR Activates a TAZ-Driven Oncogenic Program in Glioblastoma. Gao M; Fu Y; Zhou W; Gui G; Lal B; Li Y; Xia S; Ji H; Eberhart CG; Laterra J; Ying M Cancer Res; 2021 Jul; 81(13):3580-3592. PubMed ID: 33910930 [TBL] [Abstract][Full Text] [Related]
13. Expression and pharmacological inhibition of TrkB and EGFR in glioblastoma. Pinheiro KV; Thomaz A; Souza BK; Metcalfe VA; Freire NH; Brunetto AT; de Farias CB; Jaeger M; Bambini V; Smith CGS; Shaw L; Roesler R Mol Biol Rep; 2020 Sep; 47(9):6817-6828. PubMed ID: 32862352 [TBL] [Abstract][Full Text] [Related]
14. Differentiation of glioblastoma multiforme stem-like cells leads to downregulation of EGFR and EGFRvIII and decreased tumorigenic and stem-like cell potential. Stockhausen MT; Kristoffersen K; Stobbe L; Poulsen HS Cancer Biol Ther; 2014 Feb; 15(2):216-24. PubMed ID: 24525857 [TBL] [Abstract][Full Text] [Related]
16. Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, inhibits colorectal cancer stem cell growth. He Y; Liu S; Newburg DS Biomed Pharmacother; 2021 Dec; 144():112339. PubMed ID: 34656057 [TBL] [Abstract][Full Text] [Related]
17. Brain-Mimetic 3D Culture Platforms Allow Investigation of Cooperative Effects of Extracellular Matrix Features on Therapeutic Resistance in Glioblastoma. Xiao W; Zhang R; Sohrabi A; Ehsanipour A; Sun S; Liang J; Walthers CM; Ta L; Nathanson DA; Seidlits SK Cancer Res; 2018 Mar; 78(5):1358-1370. PubMed ID: 29282221 [TBL] [Abstract][Full Text] [Related]
18. Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival. Luchman HA; Stechishin OD; Nguyen SA; Lun XQ; Cairncross JG; Weiss S Clin Cancer Res; 2014 Nov; 20(22):5756-67. PubMed ID: 25316808 [TBL] [Abstract][Full Text] [Related]
19. Mechanisms of Resistance to EGFR Inhibition Reveal Metabolic Vulnerabilities in Human GBM. McKinney A; Lindberg OR; Engler JR; Chen KY; Kumar A; Gong H; Lu KV; Simonds EF; Cloughesy TF; Liau LM; Prados M; Bollen AW; Berger MS; Shieh JTC; James CD; Nicolaides TP; Yong WH; Lai A; Hegi ME; Weiss WA; Phillips JJ Mol Cancer Ther; 2019 Sep; 18(9):1565-1576. PubMed ID: 31270152 [TBL] [Abstract][Full Text] [Related]
20. The third-generation EGFR inhibitor AZD9291 overcomes primary resistance by continuously blocking ERK signaling in glioblastoma. Liu X; Chen X; Shi L; Shan Q; Cao Q; Yue C; Li H; Li S; Wang J; Gao S; Niu M; Yu R J Exp Clin Cancer Res; 2019 May; 38(1):219. PubMed ID: 31122294 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]