These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 22746203)

  • 21. Novel Bacterial Topoisomerase Inhibitors with Potent Broad-Spectrum Activity against Drug-Resistant Bacteria.
    Charrier C; Salisbury AM; Savage VJ; Duffy T; Moyo E; Chaffer-Malam N; Ooi N; Newman R; Cheung J; Metzger R; McGarry D; Pichowicz M; Sigerson R; Cooper IR; Nelson G; Butler HS; Craighead M; Ratcliffe AJ; Best SA; Stokes NR
    Antimicrob Agents Chemother; 2017 May; 61(5):. PubMed ID: 28223393
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: intelligent design and evolution through the judicious use of structure-guided design and structure-activity relationships.
    Charifson PS; Grillot AL; Grossman TH; Parsons JD; Badia M; Bellon S; Deininger DD; Drumm JE; Gross CH; LeTiran A; Liao Y; Mani N; Nicolau DP; Perola E; Ronkin S; Shannon D; Swenson LL; Tang Q; Tessier PR; Tian SK; Trudeau M; Wang T; Wei Y; Zhang H; Stamos D
    J Med Chem; 2008 Sep; 51(17):5243-63. PubMed ID: 18690678
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cleavable-complex formation by wild-type and quinolone-resistant Streptococcus pneumoniae type II topoisomerases mediated by gemifloxacin and other fluoroquinolones.
    Yague G; Morris JE; Pan XS; Gould KA; Fisher LM
    Antimicrob Agents Chemother; 2002 Feb; 46(2):413-9. PubMed ID: 11796351
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities.
    Aziz HA; El-Saghier AMM; Badr M; Abuo-Rahma GEA; Shoman ME
    Mol Divers; 2022 Jun; 26(3):1743-1759. PubMed ID: 34455532
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design, synthesis, in vitro antimicrobial evaluation and molecular docking studies of indol-2-one tagged with morpholinosulfonyl moiety as DNA gyrase inhibitors.
    Salem MA; Ragab A; El-Khalafawy A; Makhlouf AH; Askar AA; Ammar YA
    Bioorg Chem; 2020 Mar; 96():103619. PubMed ID: 32036161
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases.
    Blanche F; Cameron B; Bernard FX; Maton L; Manse B; Ferrero L; Ratet N; Lecoq C; Goniot A; Bisch D; Crouzet J
    Antimicrob Agents Chemother; 1996 Dec; 40(12):2714-20. PubMed ID: 9124828
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Interactions between Zoliflodacin and
    Collins JA; Basarab GS; Chibale K; Osheroff N
    ACS Infect Dis; 2024 Aug; 10(8):3071-3082. PubMed ID: 39082980
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site.
    Tomašič T; Katsamakas S; Hodnik Ž; Ilaš J; Brvar M; Solmajer T; Montalvão S; Tammela P; Banjanac M; Ergović G; Anderluh M; Peterlin Mašič L; Kikelj D
    J Med Chem; 2015 Jul; 58(14):5501-21. PubMed ID: 26098163
    [TBL] [Abstract][Full Text] [Related]  

  • 29. An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors.
    Tiz DB; Skok Ž; Durcik M; Tomašič T; Mašič LP; Ilaš J; Zega A; Draskovits G; Révész T; Nyerges Á; Pál C; Cruz CD; Tammela P; Žigon D; Kikelj D; Zidar N
    Eur J Med Chem; 2019 Apr; 167():269-290. PubMed ID: 30776691
    [TBL] [Abstract][Full Text] [Related]  

  • 30. New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.
    Durcik M; Lovison D; Skok Ž; Durante Cruz C; Tammela P; Tomašič T; Benedetto Tiz D; Draskovits G; Nyerges Á; Pál C; Ilaš J; Peterlin Mašič L; Kikelj D; Zidar N
    Eur J Med Chem; 2018 Jun; 154():117-132. PubMed ID: 29778894
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Triaryl Benzimidazoles as a New Class of Antibacterial Agents against Resistant Pathogenic Microorganisms.
    Picconi P; Hind C; Jamshidi S; Nahar K; Clifford M; Wand ME; Sutton JM; Rahman KM
    J Med Chem; 2017 Jul; 60(14):6045-6059. PubMed ID: 28650661
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
    Ibrahim TS; Almalki AJ; Moustafa AH; Allam RM; Abuo-Rahma GEA; El Subbagh HI; Mohamed MFA
    Bioorg Chem; 2021 Jun; 111():104885. PubMed ID: 33838559
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design, Synthesis, and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors.
    Cotman AE; Trampuž M; Brvar M; Kikelj D; Ilaš J; Peterlin-Mašič L; Montalvão S; Tammela P; Frlan R
    Arch Pharm (Weinheim); 2017 Aug; 350(8):. PubMed ID: 28621824
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Evaluation of WO2012177707 and WO2012097269: Vertex's phosphate prodrugs of gyrase and topoisomerase antibacterial agents.
    Finn J
    Expert Opin Ther Pat; 2013 Sep; 23(9):1233-7. PubMed ID: 23924360
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors.
    Liu JJ; Sun J; Fang YB; Yang YA; Jiao RH; Zhu HL
    Org Biomol Chem; 2014 Feb; 12(6):998-1008. PubMed ID: 24382549
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibition.
    Takei M; Fukuda H; Kishii R; Hosaka M
    Antimicrob Agents Chemother; 2001 Dec; 45(12):3544-7. PubMed ID: 11709337
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and antibacterial activity of novel and potent DNA gyrase inhibitors with azole ring.
    Tanitame A; Oyamada Y; Ofuji K; Fujimoto M; Suzuki K; Ueda T; Terauchi H; Kawasaki M; Nagai K; Wachi M; Yamagishi J
    Bioorg Med Chem; 2004 Nov; 12(21):5515-24. PubMed ID: 15465328
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors.
    Axford LC; Agarwal PK; Anderson KH; Andrau LN; Atherall J; Barker S; Bennett JM; Blair M; Collins I; Czaplewski LG; Davies DT; Gannon CT; Kumar D; Lancett P; Logan A; Lunniss CJ; Mitchell DR; Offermann DA; Palmer JT; Palmer N; Pitt GR; Pommier S; Price D; Narasinga Rao B; Saxena R; Shukla T; Singh AK; Singh M; Srivastava A; Steele C; Stokes NR; Thomaides-Brears HB; Tyndall EM; Watson D; Haydon DJ
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6598-603. PubMed ID: 24239017
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Antibacterial Spiropyrimidinetriones with N-Linked Azole Substituents on a Benzisoxazole Scaffold Targeting DNA Gyrase.
    Basarab GS; Doig P; Eyermann CJ; Galullo V; Kern G; Kimzey A; Kutschke A; Morningstar M; Schuck V; Vishwanathan K; Zhou F; Gowravaram M; Hauck S
    J Med Chem; 2020 Oct; 63(20):11882-11901. PubMed ID: 32914979
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mechanism of inhibition of DNA gyrase by ES-1273, a novel DNA gyrase inhibitor.
    Oyamada Y; Yamagishi J; Kihara T; Yoshida H; Wachi M; Ito H
    Microbiol Immunol; 2007; 51(10):977-84. PubMed ID: 17951987
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.