74 related articles for article (PubMed ID: 22747506)
1. Structural characteristics determine the cause of the low enzyme activity of two thiopurine S-methyltransferase allelic variants: a biophysical characterization of TPMT*2 and TPMT*5.
Wennerstrand P; Dametto P; Hennig J; Klingstedt T; Skoglund K; Appell ML; Mårtensson LG
Biochemistry; 2012 Jul; 51(30):5912-20. PubMed ID: 22747506
[TBL] [Abstract][Full Text] [Related]
2. Characterization of a novel sequence variant, TPMT*28, in the human thiopurine methyltransferase gene.
Appell ML; Wennerstrand P; Peterson C; Hertervig E; Mårtensson LG
Pharmacogenet Genomics; 2010 Nov; 20(11):700-7. PubMed ID: 20881512
[TBL] [Abstract][Full Text] [Related]
3. Functional characterization of 23 allelic variants of thiopurine S-methyltransferase gene (TPMT*2 - *24).
Ujiie S; Sasaki T; Mizugaki M; Ishikawa M; Hiratsuka M
Pharmacogenet Genomics; 2008 Oct; 18(10):887-93. PubMed ID: 18708949
[TBL] [Abstract][Full Text] [Related]
4. In Vitro Protein Stability of Two Naturally Occurring Thiopurine
Wennerstrand P; Blissing A; Mårtensson LG
ACS Omega; 2017 Aug; 2(8):4991-4999. PubMed ID: 30023734
[TBL] [Abstract][Full Text] [Related]
5. Identification and functional analysis of two rare allelic variants of the thiopurine S-methyltransferase gene, TPMT*16 and TPMT*19.
Hamdan-Khalil R; Gala JL; Allorge D; Lo-Guidice JM; Horsmans Y; Houdret N; Broly F
Biochem Pharmacol; 2005 Feb; 69(3):525-9. PubMed ID: 15652243
[TBL] [Abstract][Full Text] [Related]
6. RT-PCR permits simultaneous genotyping of thiopurine S-methyltransferase allelic variants by multiplex induced heteroduplex analysis.
Wood N; Fraser A; Bidwell J; Standen G
Hum Mutat; 2004 Jul; 24(1):93-9. PubMed ID: 15221793
[TBL] [Abstract][Full Text] [Related]
7. Human thiopurine methyltransferase: molecular cloning and expression of T84 colon carcinoma cell cDNA.
Honchel R; Aksoy IA; Szumlanski C; Wood TC; Otterness DM; Wieben ED; Weinshilboum RM
Mol Pharmacol; 1993 Jun; 43(6):878-87. PubMed ID: 8316220
[TBL] [Abstract][Full Text] [Related]
8. Four human thiopurine s-methyltransferase alleles severely affect protein structure and dynamics.
Rutherford K; Daggett V
J Mol Biol; 2008 Jun; 379(4):803-14. PubMed ID: 18482735
[TBL] [Abstract][Full Text] [Related]
9. Trinucleotide repeat variants in the promoter of the thiopurine S-methyltransferase gene of patients exhibiting ultra-high enzyme activity.
Roberts RL; Gearry RB; Bland MV; Sies CW; George PM; Burt M; Marinaki AM; Arenas M; Barclay ML; Kennedy MA
Pharmacogenet Genomics; 2008 May; 18(5):434-8. PubMed ID: 18408566
[TBL] [Abstract][Full Text] [Related]
10. Characterisation of novel defective thiopurine S-methyltransferase allelic variants.
Garat A; Cauffiez C; Renault N; Lo-Guidice JM; Allorge D; Chevalier D; Houdret N; Chavatte P; Loriot MA; Gala JL; Broly F
Biochem Pharmacol; 2008 Aug; 76(3):404-15. PubMed ID: 18602085
[TBL] [Abstract][Full Text] [Related]
11. Tracing the origin of the most common thiopurine methyltransferase (TPMT) variants: preliminary data from the patterns of haplotypic association with two CA repeats.
Alves S; Rocha J; Amorim A; Prata MJ
Ann Hum Genet; 2004 Jul; 68(Pt 4):313-23. PubMed ID: 15225157
[TBL] [Abstract][Full Text] [Related]
12. Consequences of binding an S-adenosylmethionine analogue on the structure and dynamics of the thiopurine methyltransferase protein backbone.
Scheuermann TH; Keeler C; Hodsdon ME
Biochemistry; 2004 Sep; 43(38):12198-209. PubMed ID: 15379558
[TBL] [Abstract][Full Text] [Related]
13. Thiopurine S-methyltransferase phenotype-genotype correlation in children with acute lymphoblastic leukemia.
Chrzanowska M; Kuehn M; Januszkiewicz-Lewandowska D; Kurzawski M; Droździk M
Acta Pol Pharm; 2012; 69(3):405-10. PubMed ID: 22594254
[TBL] [Abstract][Full Text] [Related]
14. Molecular analysis of the thiopurine S-methyltransferase alleles in Bolivians and Tibetans.
Lu HF; Shih MC; Hsueh SC; Chen CM; Chang JY; Chang JG
J Clin Pharm Ther; 2005 Oct; 30(5):491-6. PubMed ID: 16164497
[TBL] [Abstract][Full Text] [Related]
15. Thiopurine S-methyltransferase pharmacogenetics: variant allele functional and comparative genomics.
Salavaggione OE; Wang L; Wiepert M; Yee VC; Weinshilboum RM
Pharmacogenet Genomics; 2005 Nov; 15(11):801-15. PubMed ID: 16220112
[TBL] [Abstract][Full Text] [Related]
16. Allelic variants of the thiopurine S-methyltransferase deficiency in patients with ulcerative colitis and in healthy controls.
Corominas H; Domènech M; González D; Diaz C; Roca M; García-González MA; Peña S; Baiget M
Am J Gastroenterol; 2000 Sep; 95(9):2313-7. PubMed ID: 11007234
[TBL] [Abstract][Full Text] [Related]
17. Frequency of the thiopurine S-methyltransferase alleles in the ancient genetic population isolate of Sardinia.
Rossino R; Vincis C; Alves S; Prata MJ; Macis MD; Nucaro AL; Schirru E; Congia M
J Clin Pharm Ther; 2006 Jun; 31(3):283-7. PubMed ID: 16789994
[TBL] [Abstract][Full Text] [Related]
18. Thiopurine S-methyltransferase (TPMT) genetic polymorphisms in Mexican newborns.
González-Del Angel A; Bermúdez-López C; Alcántara-Ortigoza MA; Vela-Amieva M; Castillo-Cruz RA; Martínez V; Torres-Espíndola L
J Clin Pharm Ther; 2009 Dec; 34(6):703-8. PubMed ID: 20175804
[TBL] [Abstract][Full Text] [Related]
19. The low frequency of defective TPMT alleles in Turkish population: a study on pediatric patients with acute lymphoblastic leukemia.
Tumer TB; Ulusoy G; Adali O; Sahin G; Gozdasoglu S; Arinç E
Am J Hematol; 2007 Oct; 82(10):906-10. PubMed ID: 17617792
[TBL] [Abstract][Full Text] [Related]
20. Analysis of thiopurine S-methyltransferase polymorphism in the population of Serbia and Montenegro and mercaptopurine therapy tolerance in childhood acute lymphoblastic leukemia.
Dokmanovic L; Urosevic J; Janic D; Jovanovic N; Petrucev B; Tosic N; Pavlovic S
Ther Drug Monit; 2006 Dec; 28(6):800-6. PubMed ID: 17164697
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
