BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 22749911)

  • 1. PinX1 is involved in telomerase recruitment and regulates telomerase function by mediating its localization.
    Cheung DH; Kung HF; Huang JJ; Shaw PC
    FEBS Lett; 2012 Sep; 586(19):3166-71. PubMed ID: 22749911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Silencing PinX1 compromises telomere length maintenance as well as tumorigenicity in telomerase-positive human cancer cells.
    Zhang B; Bai YX; Ma HH; Feng F; Jin R; Wang ZL; Lin J; Sun SP; Yang P; Wang XX; Huang PT; Huang CF; Peng Y; Chen YC; Kung HF; Huang JJ
    Cancer Res; 2009 Jan; 69(1):75-83. PubMed ID: 19117989
    [TBL] [Abstract][Full Text] [Related]  

  • 3. C-terminal amino acids 290-328 of LPTS/PinX1 confer telomerase inhibition.
    Chen G; Da L; Xu Y; Xu M; Song L; Li T; Zhao M
    Biochem Biophys Res Commun; 2010 Aug; 398(4):683-9. PubMed ID: 20620128
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length.
    Song H; Li Y; Chen G; Xing Z; Zhao J; Yokoyama KK; Li T; Zhao M
    Biochem Biophys Res Commun; 2004 Apr; 316(4):1116-23. PubMed ID: 15044100
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells.
    Zuo J; Wang DH; Zhang YJ; Liu L; Liu FL; Liu W
    Oncol Rep; 2013 Oct; 30(4):1823-31. PubMed ID: 23912465
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Pinx1 Gene Downregulates Telomerase and Inhibits Proliferation of CD133+ Cancer Stem Cells Isolated from a Nasopharyngeal Carcinoma Cell Line by Regulating Trfs and Mad1/C-Myc/p53 Pathways.
    Shen C; Chen F; Wang H; Li G; Yu C; Wang X; Wen Z
    Cell Physiol Biochem; 2018; 49(1):282-294. PubMed ID: 30138944
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual roles.
    Yoo JE; Park YN; Oh BK
    J Biol Chem; 2014 Mar; 289(10):6886-6898. PubMed ID: 24415760
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human PinX1 mediates TRF1 accumulation in nucleolus and enhances TRF1 binding to telomeres.
    Yoo JE; Oh BK; Park YN
    J Mol Biol; 2009 May; 388(5):928-40. PubMed ID: 19265708
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular analysis of PinX1 in human hepatocellular carcinoma.
    Oh BK; Chae KJ; Park C; Park YN
    Oncol Rep; 2004 Oct; 12(4):861-6. PubMed ID: 15375513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plk1-mediated mitotic phosphorylation of PinX1 regulates its stability.
    Wang C; Yu J; Yuan K; Lan J; Jin C; Huang H
    Eur J Cell Biol; 2010 Oct; 89(10):748-56. PubMed ID: 20573420
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a novel effect of hPinX1 on hTERT nucleolar localization.
    Lin J; Jin R; Zhang B; Yang PX; Chen H; Bai YX; Xie Y; Huang C; Huang J
    Biochem Biophys Res Commun; 2007 Feb; 353(4):946-52. PubMed ID: 17198684
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutant telomerase RNAs induce DNA damage and apoptosis via the TRF2-ATM pathway in telomerase-overexpressing primary fibroblasts.
    Mahalingam D; Tay LL; Tan WH; Chai JH; Wang X
    FEBS J; 2011 Oct; 278(19):3724-38. PubMed ID: 21824286
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR.
    Banik SS; Counter CM
    J Biol Chem; 2004 Dec; 279(50):51745-8. PubMed ID: 15381700
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity.
    Cheung DH; Ho ST; Lau KF; Jin R; Wang YN; Kung HF; Huang JJ; Shaw PC
    Sci Rep; 2017 Mar; 7():43650. PubMed ID: 28255170
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anthracyclines disrupt telomere maintenance by telomerase through inducing PinX1 ubiquitination and degradation.
    Zhang B; Qian D; Ma HH; Jin R; Yang PX; Cai MY; Liu YH; Liao YJ; Deng HX; Mai SJ; Zhang H; Zeng YX; Lin MC; Kung HF; Xie D; Huang JJ
    Oncogene; 2012 Jan; 31(1):1-12. PubMed ID: 21643006
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor.
    Zhou XZ; Lu KP
    Cell; 2001 Nov; 107(3):347-59. PubMed ID: 11701125
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Telomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongation.
    Soohoo CY; Shi R; Lee TH; Huang P; Lu KP; Zhou XZ
    J Biol Chem; 2011 Feb; 286(5):3894-906. PubMed ID: 21119197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rat homolog of PinX1 is a nucleolar protein involved in the regulation of telomere length.
    Oh BK; Yoon SM; Lee CH; Park YN
    Gene; 2007 Oct; 400(1-2):35-43. PubMed ID: 17624691
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The telomere/telomerase binding factor PinX1 regulates paclitaxel sensitivity depending on spindle assembly checkpoint in human cervical squamous cell carcinomas.
    Tian XP; Qian D; He LR; Huang H; Mai SJ; Li CP; Huang XX; Cai MY; Liao YJ; Kung HF; Zeng YX; Xie D
    Cancer Lett; 2014 Oct; 353(1):104-14. PubMed ID: 25045845
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Silencing of the hPOT1 gene by RNA inference promotes apoptosis and inhibits proliferation and aggressive phenotype of gastric cancer cells, likely through up-regulating PinX1 expression.
    Wan SM; Tie J; Zhang YF; Guo J; Yang LQ; Wang J; Xia SH; Yang SM; Wang RQ; Fang DC
    J Clin Pathol; 2011 Dec; 64(12):1051-7. PubMed ID: 21778296
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.