BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

371 related articles for article (PubMed ID: 22751103)

  • 1. Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.
    Strong A; Ding Q; Edmondson AC; Millar JS; Sachs KV; Li X; Kumaravel A; Wang MY; Ai D; Guo L; Alexander ET; Nguyen D; Lund-Katz S; Phillips MC; Morales CR; Tall AR; Kathiresan S; Fisher EA; Musunuru K; Rader DJ
    J Clin Invest; 2012 Aug; 122(8):2807-16. PubMed ID: 22751103
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Macrophage sortilin promotes LDL uptake, foam cell formation, and atherosclerosis.
    Patel KM; Strong A; Tohyama J; Jin X; Morales CR; Billheimer J; Millar J; Kruth H; Rader DJ
    Circ Res; 2015 Feb; 116(5):789-96. PubMed ID: 25593281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.
    Ai D; Baez JM; Jiang H; Conlon DM; Hernandez-Ono A; Frank-Kamenetsky M; Milstein S; Fitzgerald K; Murphy AJ; Woo CW; Strong A; Ginsberg HN; Tabas I; Rader DJ; Tall AR
    J Clin Invest; 2012 May; 122(5):1677-87. PubMed ID: 22466652
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sortilin restricts secretion of apolipoprotein B-100 by hepatocytes under stressed but not basal conditions.
    Conlon DM; Schneider CV; Ko YA; Rodrigues A; Guo K; Hand NJ; Rader DJ
    J Clin Invest; 2022 Mar; 132(6):. PubMed ID: 35113816
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autophagy Is Required for Sortilin-Mediated Degradation of Apolipoprotein B100.
    Amengual J; Guo L; Strong A; Madrigal-Matute J; Wang H; Kaushik S; Brodsky JL; Rader DJ; Cuervo AM; Fisher EA
    Circ Res; 2018 Feb; 122(4):568-582. PubMed ID: 29301854
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export.
    Kjolby M; Andersen OM; Breiderhoff T; Fjorback AW; Pedersen KM; Madsen P; Jansen P; Heeren J; Willnow TE; Nykjaer A
    Cell Metab; 2010 Sep; 12(3):213-23. PubMed ID: 20816088
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gene transfer of cytidine deaminase apoBEC-1 lowers lipoprotein(a) in transgenic mice and induces apolipoprotein B editing in rabbits.
    Hughes SD; Rouy D; Navaratnam N; Scott J; Rubin EM
    Hum Gene Ther; 1996 Jan; 7(1):39-49. PubMed ID: 8825867
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of sortilin in lipid metabolism.
    Conlon DM
    Curr Opin Lipidol; 2019 Jun; 30(3):198-204. PubMed ID: 30946050
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Low expression of the apolipoprotein B mRNA-editing transgene in mice reduces LDL levels but does not cause liver dysplasia or tumors.
    Qian X; Balestra ME; Yamanaka S; Borén J; Lee I; Innerarity TL
    Arterioscler Thromb Vasc Biol; 1998 Jun; 18(6):1013-20. PubMed ID: 9633945
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Complete phenotypic characterization of apobec-1 knockout mice with a wild-type genetic background and a human apolipoprotein B transgenic background, and restoration of apolipoprotein B mRNA editing by somatic gene transfer of Apobec-1.
    Nakamuta M; Chang BH; Zsigmond E; Kobayashi K; Lei H; Ishida BY; Oka K; Li E; Chan L
    J Biol Chem; 1996 Oct; 271(42):25981-8. PubMed ID: 8824235
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and watanabe heritable hyperlipidemic rabbits.
    Greeve J; Jona VK; Chowdhury NR; Horwitz MS; Chowdhury JR
    J Lipid Res; 1996 Sep; 37(9):2001-17. PubMed ID: 8895066
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatic secretion of small lipoprotein particles in apobec-1-/- mice is regulated by the LDL receptor.
    Nassir F; Xie Y; Patterson BW; Luo J; Davidson NO
    J Lipid Res; 2004 Sep; 45(9):1649-59. PubMed ID: 15145984
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Studies on the binding and degradation of human very-low-density lipoproteins by human hepatoma cell line HepG2.
    Dashti N; Wolfbauer G
    Biochim Biophys Acta; 1986 Feb; 875(3):473-86. PubMed ID: 3004589
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of microRNA-378a-3p biogenesis promotes hepatic secretion of VLDL and hyperlipidemia by modulating ApoB100-Sortilin1 axis.
    Zhang T; Shi H; Liu N; Tian J; Zhao X; Steer CJ; Han Q; Song G
    Theranostics; 2020; 10(9):3952-3966. PubMed ID: 32226531
    [No Abstract]   [Full Text] [Related]  

  • 15. Sortilin enhances secretion of apolipoprotein(a) through effects on apolipoprotein B secretion and promotes uptake of lipoprotein(a).
    Clark JR; Gemin M; Youssef A; Marcovina SM; Prat A; Seidah NG; Hegele RA; Boffa MB; Koschinsky ML
    J Lipid Res; 2022 Jun; 63(6):100216. PubMed ID: 35469919
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endothelial lipase promotes the catabolism of ApoB-containing lipoproteins.
    Broedl UC; Maugeais C; Millar JS; Jin W; Moore RE; Fuki IV; Marchadier D; Glick JM; Rader DJ
    Circ Res; 2004 Jun; 94(12):1554-61. PubMed ID: 15117821
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of HMG-CoA reductase by atorvastatin decreases both VLDL and LDL apolipoprotein B production in miniature pigs.
    Burnett JR; Wilcox LJ; Telford DE; Kleinstiver SJ; Barrett PH; Newton RS; Huff MW
    Arterioscler Thromb Vasc Biol; 1997 Nov; 17(11):2589-600. PubMed ID: 9409231
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The peroxisome proliferator-activated receptor alpha (PPARalpha) agonist ciprofibrate inhibits apolipoprotein B mRNA editing in low density lipoprotein receptor-deficient mice: effects on plasma lipoproteins and the development of atherosclerotic lesions.
    Fu T; Mukhopadhyay D; Davidson NO; Borensztajn J
    J Biol Chem; 2004 Jul; 279(27):28662-9. PubMed ID: 15123680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sortilin promotes macrophage cholesterol accumulation and aortic atherosclerosis through lysosomal degradation of ATP-binding cassette transporter A1 protein.
    Lv Y; Yang J; Gao A; Sun S; Zheng X; Chen X; Wan W; Tang C; Xie W; Li S; Guo D; Peng T; Zhao G; Zhong L
    Acta Biochim Biophys Sin (Shanghai); 2019 May; 51(5):471-483. PubMed ID: 30950489
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phenotype interaction of apobec-1 and CETP, LDLR, and apoE gene expression in mice: role of apoB mRNA editing in lipoprotein phenotype expression.
    Nakamuta M; Taniguchi S; Ishida BY; Kobayashi K; Chan L
    Arterioscler Thromb Vasc Biol; 1998 May; 18(5):747-55. PubMed ID: 9598833
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.