These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

515 related articles for article (PubMed ID: 22753465)

  • 1. Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors.
    Gurney A; Axelrod F; Bond CJ; Cain J; Chartier C; Donigan L; Fischer M; Chaudhari A; Ji M; Kapoun AM; Lam A; Lazetic S; Ma S; Mitra S; Park IK; Pickell K; Sato A; Satyal S; Stroud M; Tran H; Yen WC; Lewicki J; Hoey T
    Proc Natl Acad Sci U S A; 2012 Jul; 109(29):11717-22. PubMed ID: 22753465
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Frizzled Receptors in Tumors, Focusing on Signaling, Roles, Modulation Mechanisms, and Targeted Therapies.
    Sun Y; Wang W; Zhao C
    Oncol Res; 2021 Mar; 28(6):661-674. PubMed ID: 32998794
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28.
    Le PN; McDermott JD; Jimeno A
    Pharmacol Ther; 2015 Feb; 146():1-11. PubMed ID: 25172549
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel humanized Frizzled-7-targeting antibody enhances antitumor effects of Bevacizumab against triple-negative breast cancer via blocking Wnt/β-catenin signaling pathway.
    Xie W; Zhao H; Wang F; Wang Y; He Y; Wang T; Zhang K; Yang H; Zhou Z; Shi H; Wang J; Huang G
    J Exp Clin Cancer Res; 2021 Jan; 40(1):30. PubMed ID: 33436039
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8.
    Hendaoui I; Lavergne E; Lee HS; Hong SH; Kim HZ; Parent C; Heuzé-Vourc'h N; Clément B; Musso O
    PLoS One; 2012; 7(1):e30601. PubMed ID: 22303445
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled.
    Lee HJ; Bao J; Miller A; Zhang C; Wu J; Baday YC; Guibao C; Li L; Wu D; Zheng JJ
    J Biol Chem; 2015 Dec; 290(51):30596-606. PubMed ID: 26504084
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Wnt Signaling in Cancer: Not a Binary ON:OFF Switch.
    Flanagan DJ; Vincan E; Phesse TJ
    Cancer Res; 2019 Dec; 79(23):5901-5906. PubMed ID: 31431458
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties.
    Pavlovic Z; Adams JJ; Blazer LL; Gakhal AK; Jarvik N; Steinhart Z; Robitaille M; Mascall K; Pan J; Angers S; Moffat J; Sidhu SS
    MAbs; 2018; 10(8):1157-1167. PubMed ID: 30183492
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frizzled Receptors as Potential Therapeutic Targets in Human Cancers.
    Zeng CM; Chen Z; Fu L
    Int J Mol Sci; 2018 May; 19(5):. PubMed ID: 29789460
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis.
    Romero G; Sneddon WB; Yang Y; Wheeler D; Blair HC; Friedman PA
    J Biol Chem; 2010 May; 285(19):14756-63. PubMed ID: 20212039
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer.
    Bravo DT; Yang YL; Kuchenbecker K; Hung MS; Xu Z; Jablons DM; You L
    BMC Cancer; 2013 Jul; 13():316. PubMed ID: 23815780
    [TBL] [Abstract][Full Text] [Related]  

  • 12.
    Flanagan DJ; Barker N; Costanzo NSD; Mason EA; Gurney A; Meniel VS; Koushyar S; Austin CR; Ernst M; Pearson HB; Boussioutas A; Clevers H; Phesse TJ; Vincan E
    Cancer Res; 2019 Mar; 79(5):970-981. PubMed ID: 30622113
    [TBL] [Abstract][Full Text] [Related]  

  • 13. E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling.
    Yamada K; Hori Y; Inoue S; Yamamoto Y; Iso K; Kamiyama H; Yamaguchi A; Kimura T; Uesugi M; Ito J; Matsuki M; Nakamoto K; Harada H; Yoneda N; Takemura A; Kushida I; Wakayama N; Kubara K; Kato Y; Semba T; Yokoi A; Matsukura M; Odagami T; Iwata M; Tsuruoka A; Uenaka T; Matsui J; Matsushima T; Nomoto K; Kouji H; Owa T; Funahashi Y; Ozawa Y
    Cancer Res; 2021 Feb; 81(4):1052-1062. PubMed ID: 33408116
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CDDO-Me Elicits Anti-Breast Cancer Activity by Targeting LRP6 and FZD7 Receptor Complex.
    Zhou L; Wang Z; Yu S; Xiong Y; Fan J; Lyu Y; Su Z; Song J; Liu S; Sun Q; Lu D
    J Pharmacol Exp Ther; 2020 Apr; 373(1):149-159. PubMed ID: 32015160
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
    Nile AH; de Sousa E Melo F; Mukund S; Piskol R; Hansen S; Zhou L; Zhang Y; Fu Y; Gogol EB; Kömüves LG; Modrusan Z; Angers S; Franke Y; Koth C; Fairbrother WJ; Wang W; de Sauvage FJ; Hannoush RN
    Nat Chem Biol; 2018 Jun; 14(6):582-590. PubMed ID: 29632413
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glypican-3 binds to Frizzled and plays a direct role in the stimulation of canonical Wnt signaling.
    Capurro M; Martin T; Shi W; Filmus J
    J Cell Sci; 2014 Apr; 127(Pt 7):1565-75. PubMed ID: 24496449
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy.
    Wang J; Ren XR; Piao H; Zhao S; Osada T; Premont RT; Mook RA; Morse MA; Lyerly HK; Chen W
    Biochem J; 2019 Feb; 476(3):535-546. PubMed ID: 30635359
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1.
    Tennis MA; Van Scoyk M; Heasley LE; Vandervest K; Weiser-Evans M; Freeman S; Keith RL; Simpson P; Nemenoff RA; Winn RA
    Neoplasia; 2010 Mar; 12(3):244-53. PubMed ID: 20234818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting the WNT Signaling Pathway in Cancer Therapeutics.
    Tai D; Wells K; Arcaroli J; Vanderbilt C; Aisner DL; Messersmith WA; Lieu CH
    Oncologist; 2015 Oct; 20(10):1189-98. PubMed ID: 26306903
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel recombinant human Frizzled-7 protein exhibits anti-tumor activity against triple negative breast cancer via abating Wnt/β-catenin pathway.
    Xie W; Zhang Y; He Y; Zhang K; Wan G; Huang Y; Zhou Z; Huang G; Wang J
    Int J Biochem Cell Biol; 2018 Oct; 103():45-55. PubMed ID: 30096373
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.