289 related articles for article (PubMed ID: 22763238)
21. 5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells.
Yuo CY; Lin HH; Chang YS; Yang WK; Chang JG
Ann Neurol; 2008 Jan; 63(1):26-34. PubMed ID: 17924536
[TBL] [Abstract][Full Text] [Related]
22. SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN.
Le TT; Pham LT; Butchbach ME; Zhang HL; Monani UR; Coovert DD; Gavrilina TO; Xing L; Bassell GJ; Burghes AH
Hum Mol Genet; 2005 Mar; 14(6):845-57. PubMed ID: 15703193
[TBL] [Abstract][Full Text] [Related]
23. A degron created by SMN2 exon 7 skipping is a principal contributor to spinal muscular atrophy severity.
Cho S; Dreyfuss G
Genes Dev; 2010 Mar; 24(5):438-42. PubMed ID: 20194437
[TBL] [Abstract][Full Text] [Related]
24. Combination of SMN trans-splicing and a neurotrophic factor increases the life span and body mass in a severe model of spinal muscular atrophy.
Shababi M; Glascock J; Lorson CL
Hum Gene Ther; 2011 Feb; 22(2):135-44. PubMed ID: 20804424
[TBL] [Abstract][Full Text] [Related]
25. hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing.
Kashima T; Rao N; David CJ; Manley JL
Hum Mol Genet; 2007 Dec; 16(24):3149-59. PubMed ID: 17884807
[TBL] [Abstract][Full Text] [Related]
26. Targeting SR proteins improves SMN expression in spinal muscular atrophy cells.
Wee CD; Havens MA; Jodelka FM; Hastings ML
PLoS One; 2014; 9(12):e115205. PubMed ID: 25506695
[TBL] [Abstract][Full Text] [Related]
27. Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA.
Dominguez CE; Cunningham D; Venkataramany AS; Chandler DS
Hum Genet; 2022 Feb; 141(2):239-256. PubMed ID: 35088120
[TBL] [Abstract][Full Text] [Related]
28. Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Nadal M; Anton R; Dorca-Arévalo J; Estébanez-Perpiñá E; Tizzano EF; Fuentes-Prior P
Protein Sci; 2023 Apr; 32(4):e4553. PubMed ID: 36560896
[TBL] [Abstract][Full Text] [Related]
29. Optimization of SMN trans-splicing through the analysis of SMN introns.
Shababi M; Lorson CL
J Mol Neurosci; 2012 Mar; 46(3):459-69. PubMed ID: 21826391
[TBL] [Abstract][Full Text] [Related]
30. A rare SMN2 variant in a previously unrecognized composite splicing regulatory element induces exon 7 inclusion and reduces the clinical severity of spinal muscular atrophy.
Vezain M; Saugier-Veber P; Goina E; Touraine R; Manel V; Toutain A; Fehrenbach S; Frébourg T; Pagani F; Tosi M; Martins A
Hum Mutat; 2010 Jan; 31(1):E1110-25. PubMed ID: 19953646
[TBL] [Abstract][Full Text] [Related]
31. Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.
Cartegni L; Hastings ML; Calarco JA; de Stanchina E; Krainer AR
Am J Hum Genet; 2006 Jan; 78(1):63-77. PubMed ID: 16385450
[TBL] [Abstract][Full Text] [Related]
32. Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model.
Hua Y; Sahashi K; Rigo F; Hung G; Horev G; Bennett CF; Krainer AR
Nature; 2011 Oct; 478(7367):123-6. PubMed ID: 21979052
[TBL] [Abstract][Full Text] [Related]
33. Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy.
Butchbach ME; Singh J; Thorsteinsdóttir M; Saieva L; Slominski E; Thurmond J; Andrésson T; Zhang J; Edwards JD; Simard LR; Pellizzoni L; Jarecki J; Burghes AH; Gurney ME
Hum Mol Genet; 2010 Feb; 19(3):454-67. PubMed ID: 19897588
[TBL] [Abstract][Full Text] [Related]
34. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
Kannan A; Jiang X; He L; Ahmad S; Gangwani L
Brain; 2020 Jan; 143(1):69-93. PubMed ID: 31828288
[TBL] [Abstract][Full Text] [Related]
35. A negatively acting bifunctional RNA increases survival motor neuron both in vitro and in vivo.
Dickson A; Osman E; Lorson CL
Hum Gene Ther; 2008 Nov; 19(11):1307-15. PubMed ID: 19848583
[TBL] [Abstract][Full Text] [Related]
36. A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.
Jodelka FM; Ebert AD; Duelli DM; Hastings ML
Hum Mol Genet; 2010 Dec; 19(24):4906-17. PubMed ID: 20884664
[TBL] [Abstract][Full Text] [Related]
37. High expression level of Tra2-β1 is responsible for increased SMN2 exon 7 inclusion in the testis of SMA mice.
Chen YC; Chang JG; Jong YJ; Liu TY; Yuo CY
PLoS One; 2015; 10(3):e0120721. PubMed ID: 25781985
[TBL] [Abstract][Full Text] [Related]
38. Combined treatment with the histone deacetylase inhibitor LBH589 and a splice-switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atrophy cells.
Pagliarini V; Guerra M; Di Rosa V; Compagnucci C; Sette C
J Neurochem; 2020 Apr; 153(2):264-275. PubMed ID: 31811660
[TBL] [Abstract][Full Text] [Related]
39. Extracellular pH change modulates the exon 7 splicing in SMN2 mRNA.
Chen YC; Yuo CY; Yang WK; Jong YJ; Lin HH; Chang YS; Chang JG
Mol Cell Neurosci; 2008 Oct; 39(2):268-72. PubMed ID: 18672065
[TBL] [Abstract][Full Text] [Related]
40. Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes.
Singh RN; Singh NN
Adv Neurobiol; 2018; 20():31-61. PubMed ID: 29916015
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]