BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 22763434)

  • 1. E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity.
    Guo H; Qiao G; Ying H; Li Z; Zhao Y; Liang Y; Yang L; Lipkowitz S; Penninger JM; Langdon WY; Zhang J
    Cell Rep; 2012 May; 1(5):472-82. PubMed ID: 22763434
    [TBL] [Abstract][Full Text] [Related]  

  • 2. T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b.
    Qiao G; Li Z; Molinero L; Alegre ML; Ying H; Sun Z; Penninger JM; Zhang J
    Mol Cell Biol; 2008 Apr; 28(7):2470-80. PubMed ID: 18227156
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation.
    Gruber T; Hermann-Kleiter N; Hinterleitner R; Fresser F; Schneider R; Gastl G; Penninger JM; Baier G
    Sci Signal; 2009 Jun; 2(76):ra30. PubMed ID: 19549985
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells.
    Yang B; Gay DL; MacLeod MK; Cao X; Hala T; Sweezer EM; Kappler J; Marrack P; Oliver PM
    Nat Immunol; 2008 Dec; 9(12):1356-63. PubMed ID: 18931680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells.
    Qiao G; Zhao Y; Li Z; Tang PQ; Langdon WY; Yang T; Zhang J
    J Immunol; 2013 Jul; 191(2):632-9. PubMed ID: 23749633
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions.
    Paolino M; Thien CB; Gruber T; Hinterleitner R; Baier G; Langdon WY; Penninger JM
    J Immunol; 2011 Feb; 186(4):2138-47. PubMed ID: 21248250
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.
    Fang D; Liu YC
    Nat Immunol; 2001 Sep; 2(9):870-5. PubMed ID: 11526404
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway.
    Liu J; Wan L; Liu P; Inuzuka H; Liu J; Wang Z; Wei W
    Oncotarget; 2014 Feb; 5(4):1026-37. PubMed ID: 24657926
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Negative regulation of CD40-mediated B cell responses by E3 ubiquitin ligase Casitas-B-lineage lymphoma protein-B.
    Qiao G; Lei M; Li Z; Sun Y; Minto A; Fu YX; Ying H; Quigg RJ; Zhang J
    J Immunol; 2007 Oct; 179(7):4473-9. PubMed ID: 17878343
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo.
    Wohlfert EA; Gorelik L; Mittler R; Flavell RA; Clark RB
    J Immunol; 2006 Feb; 176(3):1316-20. PubMed ID: 16424156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation.
    Tran CW; Saibil SD; Le Bihan T; Hamilton SR; Lang KS; You H; Lin AE; Garza KM; Elford AR; Tai K; Parsons ME; Wigmore K; Vainberg MG; Penninger JM; Woodgett JR; Mak TW; Ohashi PS
    J Immunol; 2017 Dec; 199(12):4056-4065. PubMed ID: 29109121
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc.
    Kwak YD; Wang B; Pan W; Xu H; Jiang X; Liao FF
    J Biol Chem; 2010 Mar; 285(13):9847-9857. PubMed ID: 20100827
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization.
    Fouladkou F; Landry T; Kawabe H; Neeb A; Lu C; Brose N; Stambolic V; Rotin D
    Proc Natl Acad Sci U S A; 2008 Jun; 105(25):8585-90. PubMed ID: 18562292
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.
    Ahn Y; Hwang CY; Lee SR; Kwon KS; Lee C
    Biochem J; 2008 Jun; 412(2):331-8. PubMed ID: 18307411
    [TBL] [Abstract][Full Text] [Related]  

  • 15. E3 ubiquitin ligase Cbl-b suppresses proallergic T cell development and allergic airway inflammation.
    Qiao G; Ying H; Zhao Y; Liang Y; Guo H; Shen H; Li Z; Solway J; Tao E; Chiang YJ; Lipkowitz S; Penninger JM; Langdon WY; Zhang J
    Cell Rep; 2014 Feb; 6(4):709-23. PubMed ID: 24508458
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p85beta phosphoinositide 3-kinase regulates CD28 coreceptor function.
    Alcázar I; Cortés I; Zaballos A; Hernandez C; Fruman DA; Barber DF; Carrera AC
    Blood; 2009 Apr; 113(14):3198-208. PubMed ID: 19190244
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.
    Hsia HE; Kumar R; Luca R; Takeda M; Courchet J; Nakashima J; Wu S; Goebbels S; An W; Eickholt BJ; Polleux F; Rotin D; Wu H; Rossner MJ; Bagni C; Rhee JS; Brose N; Kawabe H
    Proc Natl Acad Sci U S A; 2014 Sep; 111(36):13205-10. PubMed ID: 25157163
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b.
    Krawczyk CM; Jones RG; Atfield A; Bachmaier K; Arya S; Odermatt B; Ohashi PS; Penninger JM
    J Immunol; 2005 Feb; 174(3):1472-8. PubMed ID: 15661906
    [TBL] [Abstract][Full Text] [Related]  

  • 19. E3 ligase Nedd4 promotes axon branching by downregulating PTEN.
    Drinjakovic J; Jung H; Campbell DS; Strochlic L; Dwivedy A; Holt CE
    Neuron; 2010 Feb; 65(3):341-57. PubMed ID: 20159448
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway.
    Eide PW; Cekaite L; Danielsen SA; Eilertsen IA; Kjenseth A; Fykerud TA; Ågesen TH; Bruun J; Rivedal E; Lothe RA; Leithe E
    Cell Signal; 2013 Jan; 25(1):12-8. PubMed ID: 22974840
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.