307 related articles for article (PubMed ID: 22773666)
1. Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Cunha DA; Igoillo-Esteve M; Gurzov EN; Germano CM; Naamane N; Marhfour I; Fukaya M; Vanderwinden JM; Gysemans C; Mathieu C; Marselli L; Marchetti P; Harding HP; Ron D; Eizirik DL; Cnop M
Diabetes; 2012 Nov; 61(11):2763-75. PubMed ID: 22773666
[TBL] [Abstract][Full Text] [Related]
2. The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity.
Wali JA; Rondas D; McKenzie MD; Zhao Y; Elkerbout L; Fynch S; Gurzov EN; Akira S; Mathieu C; Kay TW; Overbergh L; Strasser A; Thomas HE
Cell Death Dis; 2014 Mar; 5(3):e1124. PubMed ID: 24625983
[TBL] [Abstract][Full Text] [Related]
3. p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress.
Gurzov EN; Germano CM; Cunha DA; Ortis F; Vanderwinden JM; Marchetti P; Zhang L; Eizirik DL
J Biol Chem; 2010 Jun; 285(26):19910-20. PubMed ID: 20421300
[TBL] [Abstract][Full Text] [Related]
4. CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis.
Cazanave SC; Elmi NA; Akazawa Y; Bronk SF; Mott JL; Gores GJ
Am J Physiol Gastrointest Liver Physiol; 2010 Jul; 299(1):G236-43. PubMed ID: 20430872
[TBL] [Abstract][Full Text] [Related]
5. JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis.
Prause M; Christensen DP; Billestrup N; Mandrup-Poulsen T
PLoS One; 2014; 9(1):e87067. PubMed ID: 24475223
[TBL] [Abstract][Full Text] [Related]
6. PUMA mediates ER stress-induced apoptosis in portal hypertensive gastropathy.
Tan S; Wei X; Song M; Tao J; Yang Y; Khatoon S; Liu H; Jiang J; Wu B
Cell Death Dis; 2014 Mar; 5(3):e1128. PubMed ID: 24625987
[TBL] [Abstract][Full Text] [Related]
7. Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.
Cunha DA; Ladrière L; Ortis F; Igoillo-Esteve M; Gurzov EN; Lupi R; Marchetti P; Eizirik DL; Cnop M
Diabetes; 2009 Dec; 58(12):2851-62. PubMed ID: 19720788
[TBL] [Abstract][Full Text] [Related]
8. Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation.
Barthson J; Germano CM; Moore F; Maida A; Drucker DJ; Marchetti P; Gysemans C; Mathieu C; Nuñez G; Jurisicova A; Eizirik DL; Gurzov EN
J Biol Chem; 2011 Nov; 286(45):39632-43. PubMed ID: 21937453
[TBL] [Abstract][Full Text] [Related]
9. Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53.
Li J; Lee B; Lee AS
J Biol Chem; 2006 Mar; 281(11):7260-70. PubMed ID: 16407291
[TBL] [Abstract][Full Text] [Related]
10. Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.
Akerfeldt MC; Howes J; Chan JY; Stevens VA; Boubenna N; McGuire HM; King C; Biden TJ; Laybutt DR
Diabetes; 2008 Nov; 57(11):3034-44. PubMed ID: 18591394
[TBL] [Abstract][Full Text] [Related]
11. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
McKenzie MD; Jamieson E; Jansen ES; Scott CL; Huang DC; Bouillet P; Allison J; Kay TW; Strasser A; Thomas HE
Diabetes; 2010 Mar; 59(3):644-52. PubMed ID: 19959756
[TBL] [Abstract][Full Text] [Related]
12. PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.
Santin I; Moore F; Colli ML; Gurzov EN; Marselli L; Marchetti P; Eizirik DL
Diabetes; 2011 Dec; 60(12):3279-88. PubMed ID: 21984578
[TBL] [Abstract][Full Text] [Related]
13. The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
Yu C; Cui S; Zong C; Gao W; Xu T; Gao P; Chen J; Qin D; Guan Q; Liu Y; Fu Y; Li X; Wang X
J Biol Chem; 2015 Aug; 290(34):20687-20699. PubMed ID: 26157144
[TBL] [Abstract][Full Text] [Related]
14. Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis.
Kakisaka K; Cazanave SC; Fingas CD; Guicciardi ME; Bronk SF; Werneburg NW; Mott JL; Gores GJ
Am J Physiol Gastrointest Liver Physiol; 2012 Jan; 302(1):G77-84. PubMed ID: 21995961
[TBL] [Abstract][Full Text] [Related]
15. Loss of Egr-1 sensitizes pancreatic β-cells to palmitate-induced ER stress and apoptosis.
Cheong MW; Kuo LH; Cheng YN; Tsai PJ; Ho LC; Tai HC; Chiu WT; Chen SH; Lu PJ; Shan YS; Chuang LM; Tsai YS
J Mol Med (Berl); 2015 Jul; 93(7):807-18. PubMed ID: 25737480
[TBL] [Abstract][Full Text] [Related]
16. Gene expression profiling indicate role of ER stress in miR-23a~27a~24-2 cluster induced apoptosis in HEK293T cells.
Chhabra R; Dubey R; Saini N
RNA Biol; 2011; 8(4):648-64. PubMed ID: 21593605
[TBL] [Abstract][Full Text] [Related]
17. Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiency.
Ren D; Sun J; Wang C; Ye H; Mao L; Cheng EH; Bell GI; Polonsky KS
Diabetes; 2014 Aug; 63(8):2744-50. PubMed ID: 24658302
[TBL] [Abstract][Full Text] [Related]
18. Enhanced signaling downstream of ribonucleic Acid-activated protein kinase-like endoplasmic reticulum kinase potentiates lipotoxic endoplasmic reticulum stress in human islets.
Ladrière L; Igoillo-Esteve M; Cunha DA; Brion JP; Bugliani M; Marchetti P; Eizirik DL; Cnop M
J Clin Endocrinol Metab; 2010 Mar; 95(3):1442-9. PubMed ID: 20080856
[TBL] [Abstract][Full Text] [Related]
19. Ubiquitin C-terminal hydrolase L1 is required for pancreatic beta cell survival and function in lipotoxic conditions.
Chu KY; Li H; Wada K; Johnson JD
Diabetologia; 2012 Jan; 55(1):128-40. PubMed ID: 22038515
[TBL] [Abstract][Full Text] [Related]
20. Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis.
Gurzov EN; Ortis F; Cunha DA; Gosset G; Li M; Cardozo AK; Eizirik DL
Cell Death Differ; 2009 Nov; 16(11):1539-50. PubMed ID: 19629134
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
