These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 22773874)

  • 1. Oxidation of dihydrotestosterone by human cytochromes P450 19A1 and 3A4.
    Cheng Q; Sohl CD; Yoshimoto FK; Guengerich FP
    J Biol Chem; 2012 Aug; 287(35):29554-67. PubMed ID: 22773874
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic Insights into the Regio- and Stereoselectivities of Testosterone and Dihydrotestosterone Hydroxylation Catalyzed by CYP3A4 and CYP19A1.
    Li J; Tang Y; Li W; Tu Y
    Chemistry; 2020 May; 26(28):6214-6223. PubMed ID: 32049373
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps.
    Krauser JA; Guengerich FP
    J Biol Chem; 2005 May; 280(20):19496-506. PubMed ID: 15772082
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H; Shimada T
    Arch Biochem Biophys; 1997 Oct; 346(1):161-9. PubMed ID: 9328296
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.
    Yamazaki H; Johnson WW; Ueng YF; Shimada T; Guengerich FP
    J Biol Chem; 1996 Nov; 271(44):27438-44. PubMed ID: 8910324
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.
    Yamazaki H; Shaw PM; Guengerich FP; Shimada T
    Chem Res Toxicol; 1998 Jun; 11(6):659-65. PubMed ID: 9625734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe.
    Wang H; Dick R; Yin H; Licad-Coles E; Kroetz DL; Szklarz G; Harlow G; Halpert JR; Correia MA
    Biochemistry; 1998 Sep; 37(36):12536-45. PubMed ID: 9730826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
    Yamazaki H; Nakano M; Imai Y; Ueng YF; Guengerich FP; Shimada T
    Arch Biochem Biophys; 1996 Jan; 325(2):174-82. PubMed ID: 8561495
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: enzyme specificity, interindividual distribution and metabolic contribution in human liver.
    Shou M; Martinet M; Korzekwa KR; Krausz KW; Gonzalez FJ; Gelboin HV
    Pharmacogenetics; 1998 Oct; 8(5):391-401. PubMed ID: 9825831
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein.
    Shet MS; Faulkner KM; Holmans PL; Fisher CW; Estabrook RW
    Arch Biochem Biophys; 1995 Apr; 318(2):314-21. PubMed ID: 7733659
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roles of cytochrome P450 3A enzymes in the 2-hydroxylation of 1,4-cineole, a monoterpene cyclic ether, by rat and human liver microsomes.
    Miyazawa M; Shindo M; Shimada T
    Xenobiotica; 2001 Oct; 31(10):713-23. PubMed ID: 11695850
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ; Smith TJ; Friesen MJ; Tynes RE; Yang CS; Murphy SE
    Carcinogenesis; 1997 Aug; 18(8):1623-30. PubMed ID: 9276639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Progesterone hydroxylation by cytochromes P450 2C and 3A enzymes in marmoset liver microsomes.
    Nakanishi K; Uehara S; Uno Y; Inoue T; Sasaki E; Yamazaki H
    Xenobiotica; 2018 Aug; 48(8):757-763. PubMed ID: 28762864
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone.
    Uehara S; Uno Y; Nakanishi K; Ishii S; Inoue T; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2017 May; 45(5):457-467. PubMed ID: 28196829
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.
    Yamazaki H; Ueng YF; Shimada T; Guengerich FP
    Biochemistry; 1995 Jul; 34(26):8380-9. PubMed ID: 7599128
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cooperativity in oxidations catalyzed by cytochrome P450 3A4.
    Ueng YF; Kuwabara T; Chun YJ; Guengerich FP
    Biochemistry; 1997 Jan; 36(2):370-81. PubMed ID: 9003190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast.
    Hayashi K; Sakaki T; Kominami S; Inouye K; Yabusaki Y
    Arch Biochem Biophys; 2000 Sep; 381(1):164-70. PubMed ID: 11019832
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxidation of R- and S-omeprazole stereoselectively mediated by liver microsomal cytochrome P450 2C19 enzymes from cynomolgus monkeys and common marmosets.
    Uehara S; Kawano M; Murayama N; Uno Y; Utoh M; Inoue T; Sasaki E; Yamazaki H
    Biochem Pharmacol; 2016 Nov; 120():56-62. PubMed ID: 27641812
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Testosterone 1 beta-hydroxylation by human cytochrome P450 3A4.
    Krauser JA; Voehler M; Tseng LH; Schefer AB; Godejohann M; Guengerich FP
    Eur J Biochem; 2004 Oct; 271(19):3962-9. PubMed ID: 15373842
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.