BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

331 related articles for article (PubMed ID: 22773947)

  • 1. USP11 augments TGFβ signalling by deubiquitylating ALK5.
    Al-Salihi MA; Herhaus L; Macartney T; Sapkota GP
    Open Biol; 2012 Jun; 2(6):120063. PubMed ID: 22773947
    [TBL] [Abstract][Full Text] [Related]  

  • 2. De-ubiquitinating enzyme, USP11, promotes transforming growth factor β-1 signaling through stabilization of transforming growth factor β receptor II.
    Jacko AM; Nan L; Li S; Tan J; Zhao J; Kass DJ; Zhao Y
    Cell Death Dis; 2016 Nov; 7(11):e2474. PubMed ID: 27853171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT.
    Soond SM; Chantry A
    Oncogene; 2011 May; 30(21):2451-62. PubMed ID: 21258410
    [TBL] [Abstract][Full Text] [Related]  

  • 4. USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma.
    Eichhorn PJ; Rodón L; Gonzàlez-Juncà A; Dirac A; Gili M; Martínez-Sáez E; Aura C; Barba I; Peg V; Prat A; Cuartas I; Jimenez J; García-Dorado D; Sahuquillo J; Bernards R; Baselga J; Seoane J
    Nat Med; 2012 Feb; 18(3):429-35. PubMed ID: 22344298
    [TBL] [Abstract][Full Text] [Related]  

  • 5. USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor.
    Zhang L; Zhou F; Drabsch Y; Gao R; Snaar-Jagalska BE; Mickanin C; Huang H; Sheppard KA; Porter JA; Lu CX; ten Dijke P
    Nat Cell Biol; 2012 Jun; 14(7):717-26. PubMed ID: 22706160
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tollip, an intracellular trafficking protein, is a novel modulator of the transforming growth factor-β signaling pathway.
    Zhu L; Wang L; Luo X; Zhang Y; Ding Q; Jiang X; Wang X; Pan Y; Chen Y
    J Biol Chem; 2012 Nov; 287(47):39653-63. PubMed ID: 23027871
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SMURF2 and SMAD7 induce SARA degradation via the proteasome.
    Wojtowicz S; Lee S; Chan E; Ng E; Campbell CI; Di Guglielmo GM
    Cell Signal; 2020 Aug; 72():109627. PubMed ID: 32283253
    [TBL] [Abstract][Full Text] [Related]  

  • 9. USP11 Enhances TGFβ-Induced Epithelial-Mesenchymal Plasticity and Human Breast Cancer Metastasis.
    Garcia DA; Baek C; Estrada MV; Tysl T; Bennett EJ; Yang J; Chang JT
    Mol Cancer Res; 2018 Jul; 16(7):1172-1184. PubMed ID: 29724812
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.
    Goumans MJ; Valdimarsdottir G; Itoh S; Lebrin F; Larsson J; Mummery C; Karlsson S; ten Dijke P
    Mol Cell; 2003 Oct; 12(4):817-28. PubMed ID: 14580334
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth.
    Daly AC; Randall RA; Hill CS
    Mol Cell Biol; 2008 Nov; 28(22):6889-902. PubMed ID: 18794361
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TGFbeta induces SIK to negatively regulate type I receptor kinase signaling.
    Kowanetz M; Lönn P; Vanlandewijck M; Kowanetz K; Heldin CH; Moustakas A
    J Cell Biol; 2008 Aug; 182(4):655-62. PubMed ID: 18725536
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligase.
    Lönn P; Vanlandewijck M; Raja E; Kowanetz M; Watanabe Y; Kowanetz K; Vasilaki E; Heldin CH; Moustakas A
    J Biol Chem; 2012 Apr; 287(16):12867-78. PubMed ID: 22378783
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TSC-22 promotes transforming growth factor β-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity.
    Yan X; Zhang J; Pan L; Wang P; Xue H; Zhang L; Gao X; Zhao X; Ning Y; Chen YG
    Mol Cell Biol; 2011 Sep; 31(18):3700-9. PubMed ID: 21791611
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice.
    Carvalho RL; Itoh F; Goumans MJ; Lebrin F; Kato M; Takahashi S; Ema M; Itoh S; van Rooijen M; Bertolino P; Ten Dijke P; Mummery CL
    J Cell Sci; 2007 Dec; 120(Pt 24):4269-77. PubMed ID: 18029401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. E3 Ubiquitin Ligases: Key Regulators of TGFβ Signaling in Cancer Progression.
    Sinha A; Iyengar PV; Ten Dijke P
    Int J Mol Sci; 2021 Jan; 22(2):. PubMed ID: 33418880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch.
    Liu IM; Schilling SH; Knouse KA; Choy L; Derynck R; Wang XF
    EMBO J; 2009 Jan; 28(2):88-98. PubMed ID: 19096363
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of ΔNp63α via a novel TGFβ/ALK5 signaling mechanism mediates the anti-clonogenic effects of TGFβ.
    Cherukuri P; DeCastro AJ; Balboni AL; Downey SL; Liu JY; Hutchinson JA; DiRenzo J
    PLoS One; 2012; 7(11):e50066. PubMed ID: 23166821
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.
    DeMaio L; Buckley ST; Krishnaveni MS; Flodby P; Dubourd M; Banfalvi A; Xing Y; Ehrhardt C; Minoo P; Zhou B; Crandall ED; Borok Z
    J Pathol; 2012 Mar; 226(4):633-44. PubMed ID: 21984393
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ubiquitin-specific peptidase 11 promotes development of keloid derived fibroblasts by de-ubiquitinating TGF-β receptorII.
    Li T; Huang J; Zeng A; Yu N; Long X
    Burns; 2024 Apr; 50(3):641-652. PubMed ID: 38097445
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.