These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 22775318)

  • 1. Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2.
    Mládková J; Vaněk V; Buděšínský M; Elbert T; Demianová Z; Garrow TA; Jiráček J
    J Med Chem; 2012 Aug; 55(15):6822-31. PubMed ID: 22775318
    [TBL] [Abstract][Full Text] [Related]  

  • 2. S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase.
    Jiracek J; Collinsova M; Rosenberg I; Budesinsky M; Protivinska E; Netusilova H; Garrow TA
    J Med Chem; 2006 Jun; 49(13):3982-9. PubMed ID: 16789755
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase.
    Pícha J; Vaněk V; Buděšínský M; Mládková J; Garrow TA; Jiráček J
    Eur J Med Chem; 2013 Jul; 65():256-75. PubMed ID: 23727536
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase.
    Vanek V; Budesínský M; Kabeleová P; Sanda M; Kozísek M; Hanclová I; Mládková J; Brynda J; Rosenberg I; Koutmos M; Garrow TA; Jirácek J
    J Med Chem; 2009 Jun; 52(12):3652-65. PubMed ID: 19534555
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.
    Szegedi SS; Castro CC; Koutmos M; Garrow TA
    J Biol Chem; 2008 Apr; 283(14):8939-45. PubMed ID: 18230605
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.
    Castro C; Gratson AA; Evans JC; Jiracek J; Collinsová M; Ludwig ML; Garrow TA
    Biochemistry; 2004 May; 43(18):5341-51. PubMed ID: 15122900
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.
    Mládková J; Hladílková J; Diamond CE; Tryon K; Yamada K; Garrow TA; Jungwirth P; Koutmos M; Jiráček J
    Proteins; 2014 Oct; 82(10):2552-64. PubMed ID: 24895213
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of recombinant human betaine: homocysteine S-methyltransferase for x-ray crystallographic studies and further characterization of interaction with S-adenosylmethionine.
    Bose N; Greenspan P; Momany C
    Protein Expr Purif; 2002 Jun; 25(1):73-80. PubMed ID: 12071701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Betaine-homocysteine methyltransferase (BHMT): genomic sequencing and relevance to hyperhomocysteinemia and vascular disease in humans.
    Heil SG; Lievers KJ; Boers GH; Verhoef P; den Heijer M; Trijbels FJ; Blom HJ
    Mol Genet Metab; 2000 Nov; 71(3):511-9. PubMed ID: 11073719
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatic betaine-homocysteine methyltransferase activity in the chicken is influenced by dietary intake of sulfur amino acids, choline and betaine.
    Emmert JL; Garrow TA; Baker DH
    J Nutr; 1996 Aug; 126(8):2050-8. PubMed ID: 8759379
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conformation-dependent inactivation of human betaine-homocysteine S-methyltransferase by hydrogen peroxide in vitro.
    Miller CM; Szegedi SS; Garrow TA
    Biochem J; 2005 Dec; 392(Pt 3):443-8. PubMed ID: 16038618
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats.
    Strakova J; Williams KT; Gupta S; Schalinske KL; Kruger WD; Rozen R; Jiracek J; Li L; Garrow TA
    Nutr Res; 2010 Jul; 30(7):492-500. PubMed ID: 20797482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver.
    Ratnam S; Wijekoon EP; Hall B; Garrow TA; Brosnan ME; Brosnan JT
    Am J Physiol Endocrinol Metab; 2006 May; 290(5):E933-9. PubMed ID: 16352668
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantification of homocysteine-related metabolites and the role of betaine-homocysteine S-methyltransferase in HepG2 cells.
    Kořínek M; Sístek V; Mládková J; Mikeš P; Jiráček J; Selicharová I
    Biomed Chromatogr; 2013 Jan; 27(1):111-21. PubMed ID: 22653757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human betaine-homocysteine methyltransferase is a zinc metalloenzyme.
    Millian NS; Garrow TA
    Arch Biochem Biophys; 1998 Aug; 356(1):93-8. PubMed ID: 9681996
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A nuclear-magnetic-resonance-based assay for betaine-homocysteine methyltransferase activity.
    Lee MB; Blunt JW; Lever M; George PM
    Anal Biochem; 2004 Jul; 330(2):199-205. PubMed ID: 15203325
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine.
    Ou X; Yang H; Ramani K; Ara AI; Chen H; Mato JM; Lu SC
    Biochem J; 2007 Jan; 401(1):87-96. PubMed ID: 16953798
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene.
    Sunden SL; Renduchintala MS; Park EI; Miklasz SD; Garrow TA
    Arch Biochem Biophys; 1997 Sep; 345(1):171-4. PubMed ID: 9281325
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?
    Pajares MA; Pérez-Sala D
    Cell Mol Life Sci; 2006 Dec; 63(23):2792-803. PubMed ID: 17086380
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro modification of betaine-homocysteine S-methyltransferase by tissue-type transglutaminase.
    Ichikawa A; Ohashi Y; Terada S; Natsuka S; Ikura K
    Int J Biochem Cell Biol; 2004 Oct; 36(10):1981-92. PubMed ID: 15203112
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.