848 related articles for article (PubMed ID: 22782619)
1. Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo.
Jayaraman M; Ansell SM; Mui BL; Tam YK; Chen J; Du X; Butler D; Eltepu L; Matsuda S; Narayanannair JK; Rajeev KG; Hafez IM; Akinc A; Maier MA; Tracy MA; Cullis PR; Madden TD; Manoharan M; Hope MJ
Angew Chem Int Ed Engl; 2012 Aug; 51(34):8529-33. PubMed ID: 22782619
[TBL] [Abstract][Full Text] [Related]
2. Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.
Basha G; Novobrantseva TI; Rosin N; Tam YY; Hafez IM; Wong MK; Sugo T; Ruda VM; Qin J; Klebanov B; Ciufolini M; Akinc A; Tam YK; Hope MJ; Cullis PR
Mol Ther; 2011 Dec; 19(12):2186-200. PubMed ID: 21971424
[TBL] [Abstract][Full Text] [Related]
3. Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA.
Chen S; Tam YYC; Lin PJC; Sung MMH; Tam YK; Cullis PR
J Control Release; 2016 Aug; 235():236-244. PubMed ID: 27238441
[TBL] [Abstract][Full Text] [Related]
4. Biodegradable lipid nanoparticles induce a prolonged RNA interference-mediated protein knockdown and show rapid hepatic clearance in mice and nonhuman primates.
Suzuki Y; Hyodo K; Suzuki T; Tanaka Y; Kikuchi H; Ishihara H
Int J Pharm; 2017 Mar; 519(1-2):34-43. PubMed ID: 28089936
[TBL] [Abstract][Full Text] [Related]
5. Lipid nanoparticles for short interfering RNA delivery.
Leung AK; Tam YY; Cullis PR
Adv Genet; 2014; 88():71-110. PubMed ID: 25409604
[TBL] [Abstract][Full Text] [Related]
6. Elucidation of the physicochemical properties and potency of siRNA-loaded small-sized lipid nanoparticles for siRNA delivery.
Sato Y; Note Y; Maeki M; Kaji N; Baba Y; Tokeshi M; Harashima H
J Control Release; 2016 May; 229():48-57. PubMed ID: 26995758
[TBL] [Abstract][Full Text] [Related]
7. Lipid-based nanoparticles in the systemic delivery of siRNA.
Lin Q; Chen J; Zhang Z; Zheng G
Nanomedicine (Lond); 2014 Jan; 9(1):105-20. PubMed ID: 24354813
[TBL] [Abstract][Full Text] [Related]
8. Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.
Tao W; Davide JP; Cai M; Zhang GJ; South VJ; Matter A; Ng B; Zhang Y; Sepp-Lorenzino L
Mol Ther; 2010 Sep; 18(9):1657-66. PubMed ID: 20628357
[TBL] [Abstract][Full Text] [Related]
9. Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration.
Chen S; Tam YY; Lin PJ; Leung AK; Tam YK; Cullis PR
J Control Release; 2014 Dec; 196():106-12. PubMed ID: 25285610
[TBL] [Abstract][Full Text] [Related]
10. Neutralization of negative charges of siRNA results in improved safety and efficient gene silencing activity of lipid nanoparticles loaded with high levels of siRNA.
Sato Y; Matsui H; Sato R; Harashima H
J Control Release; 2018 Aug; 284():179-187. PubMed ID: 29936118
[TBL] [Abstract][Full Text] [Related]
11. Effect of PEGylation on biodistribution and gene silencing of siRNA/lipid nanoparticle complexes.
Bao Y; Jin Y; Chivukula P; Zhang J; Liu Y; Liu J; Clamme JP; Mahato RI; Ng D; Ying W; Wang Y; Yu L
Pharm Res; 2013 Feb; 30(2):342-51. PubMed ID: 22983644
[TBL] [Abstract][Full Text] [Related]
12. Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo.
Sato Y; Hashiba K; Sasaki K; Maeki M; Tokeshi M; Harashima H
J Control Release; 2019 Feb; 295():140-152. PubMed ID: 30610950
[TBL] [Abstract][Full Text] [Related]
13. pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes.
Hashiba K; Sato Y; Harashima H
J Control Release; 2017 Sep; 262():239-246. PubMed ID: 28774839
[TBL] [Abstract][Full Text] [Related]
14. The role of disulfide-bridge on the activities of H-shape gemini-like cationic lipid based siRNA delivery.
Ma XF; Sun J; Qiu C; Wu YF; Zheng Y; Yu MZ; Pei XW; Wei L; Niu YJ; Pang WH; Yang ZJ; Wang JC; Zhang Q
J Control Release; 2016 Aug; 235():99-111. PubMed ID: 27242198
[TBL] [Abstract][Full Text] [Related]
15. Enhancing siRNA delivery by employing lipid nanoparticles.
Hope MJ
Ther Deliv; 2014 Jun; 5(6):663-73. PubMed ID: 25090280
[TBL] [Abstract][Full Text] [Related]
16. Enhanced Delivery of siRNA to Retinal Ganglion Cells by Intravitreal Lipid Nanoparticles of Positive Charge.
Huang X; Chau Y
Mol Pharm; 2021 Jan; 18(1):377-385. PubMed ID: 33295773
[TBL] [Abstract][Full Text] [Related]
17. siRNA-lipid nanoparticles with long-term storage stability facilitate potent gene-silencing in vivo.
Suzuki Y; Hyodo K; Tanaka Y; Ishihara H
J Control Release; 2015 Dec; 220(Pt A):44-50. PubMed ID: 26478014
[TBL] [Abstract][Full Text] [Related]
18. The development of tertiary amine cationic lipids for safe and efficient siRNA delivery.
Lin Z; Bao M; Yu Z; Xue L; Ju C; Zhang C
Biomater Sci; 2019 Jul; 7(7):2777-2792. PubMed ID: 31041934
[TBL] [Abstract][Full Text] [Related]
19. A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells.
Warashina S; Nakamura T; Sato Y; Fujiwara Y; Hyodo M; Hatakeyama H; Harashima H
J Control Release; 2016 Mar; 225():183-91. PubMed ID: 26820519
[TBL] [Abstract][Full Text] [Related]
20. Multifunctional pH-Sensitive Amino Lipids for siRNA Delivery.
Gujrati M; Vaidya A; Lu ZR
Bioconjug Chem; 2016 Jan; 27(1):19-35. PubMed ID: 26629982
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]