BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

728 related articles for article (PubMed ID: 22786682)

  • 1. PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.
    Tsunemi T; Ashe TD; Morrison BE; Soriano KR; Au J; Roque RA; Lazarowski ER; Damian VA; Masliah E; La Spada AR
    Sci Transl Med; 2012 Jul; 4(142):142ra97. PubMed ID: 22786682
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease.
    Jin J; Albertz J; Guo Z; Peng Q; Rudow G; Troncoso JC; Ross CA; Duan W
    J Neurochem; 2013 May; 125(3):410-9. PubMed ID: 23373812
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PPARGC1A/PGC-1α, TFEB and enhanced proteostasis in Huntington disease: defining regulatory linkages between energy production and protein-organelle quality control.
    La Spada AR
    Autophagy; 2012 Dec; 8(12):1845-7. PubMed ID: 22932698
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
    Cui L; Jeong H; Borovecki F; Parkhurst CN; Tanese N; Krainc D
    Cell; 2006 Oct; 127(1):59-69. PubMed ID: 17018277
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease.
    Hathorn T; Snyder-Keller A; Messer A
    Neurobiol Dis; 2011 Jan; 41(1):43-50. PubMed ID: 20736066
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
    Weydt P; Pineda VV; Torrence AE; Libby RT; Satterfield TF; Lazarowski ER; Gilbert ML; Morton GJ; Bammler TK; Strand AD; Cui L; Beyer RP; Easley CN; Smith AC; Krainc D; Luquet S; Sweet IR; Schwartz MW; La Spada AR
    Cell Metab; 2006 Nov; 4(5):349-62. PubMed ID: 17055784
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exercise induces TFEB expression and activity in skeletal muscle in a PGC-1α-dependent manner.
    Erlich AT; Brownlee DM; Beyfuss K; Hood DA
    Am J Physiol Cell Physiol; 2018 Jan; 314(1):C62-C72. PubMed ID: 29046293
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PGC-1α, mitochondrial dysfunction, and Huntington's disease.
    Johri A; Chandra A; Flint Beal M
    Free Radic Biol Med; 2013 Sep; 62():37-46. PubMed ID: 23602910
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease.
    Chaturvedi RK; Hennessey T; Johri A; Tiwari SK; Mishra D; Agarwal S; Kim YS; Beal MF
    Hum Mol Genet; 2012 Aug; 21(15):3474-88. PubMed ID: 22589249
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The dysfunction of hepatic transcriptional factors in mice with Huntington's Disease.
    Chiang MC; Chern Y; Juo CG
    Biochim Biophys Acta; 2011 Sep; 1812(9):1111-20. PubMed ID: 21651979
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation.
    Chaturvedi RK; Calingasan NY; Yang L; Hennessey T; Johri A; Beal MF
    Hum Mol Genet; 2010 Aug; 19(16):3190-205. PubMed ID: 20529956
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease.
    Chiang MC; Chern Y; Huang RN
    Neurobiol Dis; 2012 Jan; 45(1):322-8. PubMed ID: 21907283
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of PGC-1α expression by a GSK-3β-TFEB signaling axis in skeletal muscle.
    Theeuwes WF; Gosker HR; Schols AMWJ; Langen RCJ; Remels AHV
    Biochim Biophys Acta Mol Cell Res; 2020 Feb; 1867(2):118610. PubMed ID: 31738957
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.
    Vodicka P; Chase K; Iuliano M; Tousley A; Valentine DT; Sapp E; Kegel-Gleason KB; Sena-Esteves M; Aronin N; DiFiglia M
    J Huntingtons Dis; 2016 Oct; 5(3):249-260. PubMed ID: 27689619
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activating mitochondrial regulator PGC-1α expression by astrocytic NGF is a therapeutic strategy for Huntington's disease.
    Chen LW; Horng LY; Wu CL; Sung HC; Wu RT
    Neuropharmacology; 2012 Sep; 63(4):719-32. PubMed ID: 22633948
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PGC-1α at the intersection of bioenergetics regulation and neuron function: from Huntington's disease to Parkinson's disease and beyond.
    Tsunemi T; La Spada AR
    Prog Neurobiol; 2012 May; 97(2):142-51. PubMed ID: 22100502
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease.
    Johri A; Calingasan NY; Hennessey TM; Sharma A; Yang L; Wille E; Chandra A; Beal MF
    Hum Mol Genet; 2012 Mar; 21(5):1124-37. PubMed ID: 22095692
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PGC-1alpha, a new therapeutic target in Huntington's disease?
    McGill JK; Beal MF
    Cell; 2006 Nov; 127(3):465-8. PubMed ID: 17081970
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcription factor EB modulates the homeostasis of reactive oxygen species in intestinal epithelial cells to alleviate inflammatory bowel disease.
    Zhang T; Zhang R; Liu W; Qi Y; Wang H; Zhang H; Xiao Z; Pandol SJ; Han YP; Zheng X
    Biochim Biophys Acta Mol Basis Dis; 2024 Jun; 1870(5):167065. PubMed ID: 38342419
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter.
    Martin E; Betuing S; Pagès C; Cambon K; Auregan G; Deglon N; Roze E; Caboche J
    Hum Mol Genet; 2011 Jun; 20(12):2422-34. PubMed ID: 21493629
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.