BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 22789429)

  • 1. Design, synthesis and biological evaluation of novel acrylamide analogues as inhibitors of BCR-ABL kinase.
    Li S; Yao Z; Zhao Y; Chen W; Wang H; Kuang X; Zhan W; Yao S; Yu S; Hu W
    Bioorg Med Chem Lett; 2012 Aug; 22(16):5279-82. PubMed ID: 22789429
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitors.
    Asaki T; Sugiyama Y; Hamamoto T; Higashioka M; Umehara M; Naito H; Niwa T
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1421-5. PubMed ID: 16332440
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of novel 2-phenylaminopyrimidine (PAP) derivatives and their antiproliferative effects in human chronic myeloid leukemia cells.
    Chang S; Yin SL; Wang J; Jing YK; Dong JH
    Molecules; 2009 Oct; 14(10):4166-79. PubMed ID: 19924055
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of compound 584, an Abl kinase inhibitor with lasting effects.
    Puttini M; Redaelli S; Moretti L; Brussolo S; Gunby RH; Mologni L; Marchesi E; Cleris L; Donella-Deana A; Drueckes P; Sala E; Lucchini V; Kubbutat M; Formelli F; Zambon A; Scapozza L; Gambacorti-Passerini C
    Haematologica; 2008 May; 93(5):653-61. PubMed ID: 18367480
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluations of novel 3-amino-4-ethynyl indazole derivatives as Bcr-Abl kinase inhibitors with potent cellular antileukemic activity.
    El-Damasy AK; Jin H; Seo SH; Bang EK; Keum G
    Eur J Med Chem; 2020 Dec; 207():112710. PubMed ID: 32961435
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of 3-(1H-1,2,3-triazol-1-yl)benzamide derivatives as Potent Pan Bcr-Abl inhibitors including the threonine(315)→isoleucine(315) mutant.
    Li Y; Shen M; Zhang Z; Luo J; Pan X; Lu X; Long H; Wen D; Zhang F; Leng F; Li Y; Tu Z; Ren X; Ding K
    J Med Chem; 2012 Nov; 55(22):10033-46. PubMed ID: 23088644
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of novel Bcr-Abl
    Pan X; Liang L; Sun Y; Si R; Zhang Q; Wang J; Fu J; Zhang J; Zhang J
    Eur J Med Chem; 2019 Sep; 178():232-242. PubMed ID: 31185413
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia.
    Liang X; Liu X; Wang B; Zou F; Wang A; Qi S; Chen C; Zhao Z; Wang W; Qi Z; Lv F; Hu Z; Wang L; Zhang S; Liu Q; Liu J
    J Med Chem; 2016 Mar; 59(5):1984-2004. PubMed ID: 26789553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of pyridin-3-yl pyrimidines as potent Bcr-Abl inhibitors.
    Pan X; Dong J; Gao H; Wang F; Zhang Y; Wang S; Zhang J
    Chem Biol Drug Des; 2014 May; 83(5):592-9. PubMed ID: 24330598
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expanding the structural diversity of Bcr-Abl inhibitors: Hybrid molecules based on GNF-2 and Imatinib.
    Pan X; Dong J; Shao R; Su P; Shi Y; Wang J; He L
    Bioorg Med Chem Lett; 2015 Oct; 25(19):4164-8. PubMed ID: 26298495
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and preclinical evaluation of NRC-AN-019.
    Amala K; Bhujanga Rao AK; Gorantla B; Gondi CS; Rao JS
    Int J Oncol; 2013 Jan; 42(1):168-78. PubMed ID: 23151973
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synergistic interactions between DMAG and mitogen-activated protein kinase kinase 1/2 inhibitors in Bcr/abl+ leukemia cells sensitive and resistant to imatinib mesylate.
    Nguyen TK; Rahmani M; Gao N; Kramer L; Corbin AS; Druker BJ; Dent P; Grant S
    Clin Cancer Res; 2006 Apr; 12(7 Pt 1):2239-47. PubMed ID: 16609040
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and kinase inhibitory activity of new sulfonamide derivatives of pyrazolo[4,3-e][1,2,4]triazines.
    Mojzych M; Šubertová V; Bielawska A; Bielawski K; Bazgier V; Berka K; Gucký T; Fornal E; Kryštof V
    Eur J Med Chem; 2014 May; 78():217-24. PubMed ID: 24681986
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological activities of Nilotinib derivates as antitumor agents.
    Pan X; Wang F; Zhang Y; Gao H; Hu Z; Wang S; Zhang J
    Bioorg Med Chem; 2013 May; 21(9):2527-34. PubMed ID: 23538233
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological activity of 4-(imidazo[1,2-b]pyridazin-3-yl)-1H-pyrazol-1-yl-phenylbenzamide derivatives as BCR-ABL kinase inhibitors.
    Hu L; Cao T; Lv Y; Ding Y; Yang L; Zhang Q; Guo M
    Bioorg Med Chem Lett; 2016 Dec; 26(23):5830-5835. PubMed ID: 28029512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expanding the structural diversity of Bcr-Abl inhibitors: Dibenzoylpiperazin incorporated with 1H-indazol-3-amine.
    Shan Y; Dong J; Pan X; Zhang L; Zhang J; Dong Y; Wang M
    Eur J Med Chem; 2015 Nov; 104():139-47. PubMed ID: 26451772
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and biological evaluation of novel water-soluble triptolide derivatives: Antineoplastic activity against imatinib-resistant CML cells bearing T315I mutant Bcr-Abl.
    Xu F; Shi X; Li S; Cui J; Lu Z; Jin Y; Lin Y; Pang J; Pan J
    Bioorg Med Chem; 2010 Mar; 18(5):1806-15. PubMed ID: 20149665
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of novel Bcr-Abl inhibitors with diacylated piperazine as the flexible linker.
    Pan X; Dong J; Shi Y; Shao R; Wei F; Wang J; Zhang J
    Org Biomol Chem; 2015 Jul; 13(25):7050-66. PubMed ID: 26052668
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of novel Bcr-Abl inhibitors targeting myristoyl pocket and ATP site.
    Dong J; Lu W; Pan X; Su P; Shi Y; Wang J; Zhang J
    Bioorg Med Chem; 2014 Dec; 22(24):6876-84. PubMed ID: 25464886
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and antitumor activities of some new N1-(flavon-6-yl)amidrazone derivatives.
    Habashneh AY; El-Abadelah MM; Zihlif MA; Imraish A; Taha MO
    Arch Pharm (Weinheim); 2014 Jun; 347(6):415-22. PubMed ID: 24615985
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.