238 related articles for article (PubMed ID: 22789711)
1. Evaluation of organic anion-transporting polypeptide 1B1 and CYP3A4 activities in primary human hepatocytes and HepaRG cells cultured in a dynamic three-dimensional bioreactor system.
Ulvestad M; Darnell M; Molden E; Ellis E; Åsberg A; Andersson TB
J Pharmacol Exp Ther; 2012 Oct; 343(1):145-56. PubMed ID: 22789711
[TBL] [Abstract][Full Text] [Related]
2. Expression and transport function of drug uptake transporters in differentiated HepaRG cells.
Kotani N; Maeda K; Debori Y; Camus S; Li R; Chesne C; Sugiyama Y
Mol Pharm; 2012 Dec; 9(12):3434-41. PubMed ID: 22897388
[TBL] [Abstract][Full Text] [Related]
3. OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.
Ulvestad M; Björquist P; Molden E; Asberg A; Andersson TB
Biochem Pharmacol; 2011 Nov; 82(9):1219-26. PubMed ID: 21787759
[TBL] [Abstract][Full Text] [Related]
4. In vitro evaluation of major in vivo drug metabolic pathways using primary human hepatocytes and HepaRG cells in suspension and a dynamic three-dimensional bioreactor system.
Darnell M; Ulvestad M; Ellis E; Weidolf L; Andersson TB
J Pharmacol Exp Ther; 2012 Oct; 343(1):134-44. PubMed ID: 22776955
[TBL] [Abstract][Full Text] [Related]
5. Effect of cryopreservation on the activity of OATP1B1/3 and OCT1 in isolated human hepatocytes.
Badolo L; Trancart MM; Gustavsson L; Chesné C
Chem Biol Interact; 2011 Apr; 190(2-3):165-70. PubMed ID: 21356203
[TBL] [Abstract][Full Text] [Related]
6. Mechanistic Evaluation of the Complex Drug-Drug Interactions of Maraviroc: Contribution of Cytochrome P450 3A, P-Glycoprotein and Organic Anion Transporting Polypeptide 1B1.
Kimoto E; Vourvahis M; Scialis RJ; Eng H; Rodrigues AD; Varma MVS
Drug Metab Dispos; 2019 May; 47(5):493-503. PubMed ID: 30862625
[TBL] [Abstract][Full Text] [Related]
7. Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture.
Badolo L; Jensen B; Säll C; Norinder U; Kallunki P; Montanari D
Xenobiotica; 2015 Feb; 45(2):177-87. PubMed ID: 25183402
[TBL] [Abstract][Full Text] [Related]
8. Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions.
Alam K; Pahwa S; Wang X; Zhang P; Ding K; Abuznait AH; Li L; Yue W
Mol Pharm; 2016 Mar; 13(3):839-51. PubMed ID: 26750564
[TBL] [Abstract][Full Text] [Related]
9. Meta-analysis of expression of hepatic organic anion-transporting polypeptide (OATP) transporters in cellular systems relative to human liver tissue.
Badée J; Achour B; Rostami-Hodjegan A; Galetin A
Drug Metab Dispos; 2015 Apr; 43(4):424-32. PubMed ID: 25564656
[TBL] [Abstract][Full Text] [Related]
10. Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.
Kunze A; Huwyler J; Camenisch G; Poller B
Drug Metab Dispos; 2014 Sep; 42(9):1514-21. PubMed ID: 24989890
[TBL] [Abstract][Full Text] [Related]
11. Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.
Ulvestad M; Nordell P; Asplund A; Rehnström M; Jacobsson S; Holmgren G; Davidson L; Brolén G; Edsbagge J; Björquist P; Küppers-Munther B; Andersson TB
Biochem Pharmacol; 2013 Sep; 86(5):691-702. PubMed ID: 23856292
[TBL] [Abstract][Full Text] [Related]
12. Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes.
Schaefer M; Morinaga G; Matsui A; Schänzle G; Bischoff D; Süssmuth RD
Drug Metab Dispos; 2018 Feb; 46(2):166-177. PubMed ID: 29212823
[TBL] [Abstract][Full Text] [Related]
13. Phase 1 and phase 2 drug metabolism and bile acid production of HepaRG cells in a bioartificial liver in absence of dimethyl sulfoxide.
Hoekstra R; Nibourg GA; van der Hoeven TV; Plomer G; Seppen J; Ackermans MT; Camus S; Kulik W; van Gulik TM; Elferink RP; Chamuleau RA
Drug Metab Dispos; 2013 Mar; 41(3):562-7. PubMed ID: 23238784
[TBL] [Abstract][Full Text] [Related]
14. Dissecting the relative contribution of OATP1B1-mediated uptake of xenobiotics into human hepatocytes using siRNA.
Williamson B; Soars AC; Owen A; White P; Riley RJ; Soars MG
Xenobiotica; 2013 Oct; 43(10):920-31. PubMed ID: 23461378
[TBL] [Abstract][Full Text] [Related]
15. The impact of solute carrier (SLC) drug uptake transporter loss in human and rat cryopreserved hepatocytes on clearance predictions.
Lundquist P; Lööf J; Sohlenius-Sternbeck AK; Floby E; Johansson J; Bylund J; Hoogstraate J; Afzelius L; Andersson TB
Drug Metab Dispos; 2014 Mar; 42(3):469-80. PubMed ID: 24396146
[TBL] [Abstract][Full Text] [Related]
16. Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta.
Le Vee M; Gripon P; Stieger B; Fardel O
Drug Metab Dispos; 2008 Feb; 36(2):217-22. PubMed ID: 17991769
[TBL] [Abstract][Full Text] [Related]
17. Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans.
Ishiguro N; Maeda K; Kishimoto W; Saito A; Harada A; Ebner T; Roth W; Igarashi T; Sugiyama Y
Drug Metab Dispos; 2006 Jul; 34(7):1109-15. PubMed ID: 16611857
[TBL] [Abstract][Full Text] [Related]
18. Characterization of organic anion transporting polypeptide (OATP) expression and its functional contribution to the uptake of substrates in human hepatocytes.
Kimoto E; Yoshida K; Balogh LM; Bi YA; Maeda K; El-Kattan A; Sugiyama Y; Lai Y
Mol Pharm; 2012 Dec; 9(12):3535-42. PubMed ID: 23082789
[TBL] [Abstract][Full Text] [Related]
19. Drug-drug interaction between pitavastatin and various drugs via OATP1B1.
Hirano M; Maeda K; Shitara Y; Sugiyama Y
Drug Metab Dispos; 2006 Jul; 34(7):1229-36. PubMed ID: 16595711
[TBL] [Abstract][Full Text] [Related]
20. Effect of Cryopreservation on Enzyme and Transporter Activities in Suspended and Sandwich Cultured Rat Hepatocytes.
Keemink J; Deferm N; De Bruyn T; Augustijns P; Bouillon T; Annaert P
AAPS J; 2018 Feb; 20(2):33. PubMed ID: 29468289
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
