204 related articles for article (PubMed ID: 22791294)
1. Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.
Jaako P; Debnath S; Olsson K; Bryder D; Flygare J; Karlsson S
Blood; 2012 Sep; 120(11):2225-8. PubMed ID: 22791294
[TBL] [Abstract][Full Text] [Related]
2. L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway.
Payne EM; Virgilio M; Narla A; Sun H; Levine M; Paw BH; Berliner N; Look AT; Ebert BL; Khanna-Gupta A
Blood; 2012 Sep; 120(11):2214-24. PubMed ID: 22734070
[TBL] [Abstract][Full Text] [Related]
3. Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
Jaako P; Flygare J; Olsson K; Quere R; Ehinger M; Henson A; Ellis S; Schambach A; Baum C; Richter J; Larsson J; Bryder D; Karlsson S
Blood; 2011 Dec; 118(23):6087-96. PubMed ID: 21989989
[TBL] [Abstract][Full Text] [Related]
4. Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia.
Jaako P; Debnath S; Olsson K; Modlich U; Rothe M; Schambach A; Flygare J; Karlsson S
Haematologica; 2014 Dec; 99(12):1792-8. PubMed ID: 25216681
[TBL] [Abstract][Full Text] [Related]
5. Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia.
Debnath S; Jaako P; Siva K; Rothe M; Chen J; Dahl M; Gaspar HB; Flygare J; Schambach A; Karlsson S
Mol Ther; 2017 Aug; 25(8):1805-1814. PubMed ID: 28434866
[TBL] [Abstract][Full Text] [Related]
6. Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.
Flygare J; Kiefer T; Miyake K; Utsugisawa T; Hamaguchi I; Da Costa L; Richter J; Davey EJ; Matsson H; Dahl N; Wiznerowicz M; Trono D; Karlsson S
Blood; 2005 Jun; 105(12):4627-34. PubMed ID: 15626736
[TBL] [Abstract][Full Text] [Related]
7. p53-Independent cell cycle and erythroid differentiation defects in murine embryonic stem cells haploinsufficient for Diamond Blackfan anemia-proteins: RPS19 versus RPL5.
Singh SA; Goldberg TA; Henson AL; Husain-Krautter S; Nihrane A; Blanc L; Ellis SR; Lipton JM; Liu JM
PLoS One; 2014; 9(2):e89098. PubMed ID: 24558476
[TBL] [Abstract][Full Text] [Related]
8. An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray.
Ebert BL; Lee MM; Pretz JL; Subramanian A; Mak R; Golub TR; Sieff CA
Blood; 2005 Jun; 105(12):4620-6. PubMed ID: 15755903
[TBL] [Abstract][Full Text] [Related]
9. Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish.
Yadav GV; Chakraborty A; Uechi T; Kenmochi N
Int J Biochem Cell Biol; 2014 Apr; 49():1-7. PubMed ID: 24417973
[TBL] [Abstract][Full Text] [Related]
10. Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19.
Miyake K; Flygare J; Kiefer T; Utsugisawa T; Richter J; Ma Z; Wiznerowicz M; Trono D; Karlsson S
Mol Ther; 2005 Apr; 11(4):627-37. PubMed ID: 15771965
[TBL] [Abstract][Full Text] [Related]
11. Ribosomal protein S19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia.
Miyake K; Utsugisawa T; Flygare J; Kiefer T; Hamaguchi I; Richter J; Karlsson S
Stem Cells; 2008 Feb; 26(2):323-9. PubMed ID: 17962699
[TBL] [Abstract][Full Text] [Related]
12. Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies.
Boultwood J; Yip BH; Vuppusetty C; Pellagatti A; Wainscoat JS
Adv Biol Regul; 2013 Jan; 53(1):8-17. PubMed ID: 23031788
[TBL] [Abstract][Full Text] [Related]
13. Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient diamond-Blackfan anemia improves following RPS19 gene transfer.
Hamaguchi I; Flygare J; Nishiura H; Brun AC; Ooka A; Kiefer T; Ma Z; Dahl N; Richter J; Karlsson S
Mol Ther; 2003 May; 7(5 Pt 1):613-22. PubMed ID: 12718904
[TBL] [Abstract][Full Text] [Related]
14. An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity.
Bhoopalan SV; Yen JS; Mayuranathan T; Mayberry KD; Yao Y; Lillo Osuna MA; Jang Y; Liyanage JS; Blanc L; Ellis SR; Wlodarski MW; Weiss MJ
JCI Insight; 2023 Jan; 8(1):. PubMed ID: 36413407
[TBL] [Abstract][Full Text] [Related]
15. L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way.
Narla A; Payne EM; Abayasekara N; Hurst SN; Raiser DM; Look AT; Berliner N; Ebert BL; Khanna-Gupta A
Br J Haematol; 2014 Nov; 167(4):524-528. PubMed ID: 25098371
[TBL] [Abstract][Full Text] [Related]
16. L-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond-Blackfan Anemia Registry.
Vlachos A; Atsidaftos E; Lababidi ML; Muir E; Rogers ZR; Alhushki W; Bernstein J; Glader B; Gruner B; Hartung H; Knoll C; Loew T; Nalepa G; Narla A; Panigrahi AR; Sieff CA; Walkovich K; Farrar JE; Lipton JM
Pediatr Blood Cancer; 2020 Dec; 67(12):e28748. PubMed ID: 33025707
[TBL] [Abstract][Full Text] [Related]
17. Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34
Liu Y; Dahl M; Debnath S; Rothe M; Smith EM; Grahn THM; Warsi S; Chen J; Flygare J; Schambach A; Karlsson S
Haematologica; 2022 Feb; 107(2):446-456. PubMed ID: 33440921
[TBL] [Abstract][Full Text] [Related]
18. Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype.
Dahl M; Warsi S; Liu Y; Debnath S; Billing M; Siva K; Flygare J; Karlsson S
Exp Hematol; 2021 Jul; 99():44-53.e2. PubMed ID: 34126174
[TBL] [Abstract][Full Text] [Related]
19. Primary hematopoietic cells from DBA patients with mutations in RPL11 and RPS19 genes exhibit distinct erythroid phenotype in vitro.
Moniz H; Gastou M; Leblanc T; Hurtaud C; Crétien A; Lécluse Y; Raslova H; Larghero J; Croisille L; Faubladier M; Bluteau O; Lordier L; Tchernia G; Vainchenker W; Mohandas N; Da Costa L;
Cell Death Dis; 2012 Jul; 3(7):e356. PubMed ID: 22833095
[TBL] [Abstract][Full Text] [Related]
20. A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia.
Devlin EE; Dacosta L; Mohandas N; Elliott G; Bodine DM
Blood; 2010 Oct; 116(15):2826-35. PubMed ID: 20606162
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
