BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 22791882)

  • 1. Dual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the translation inhibitor silvestrol.
    Alinari L; Prince CJ; Edwards RB; Towns WH; Mani R; Lehman A; Zhang X; Jarjoura D; Pan L; Kinghorn AD; Grever MR; Baiocchi RA; Lucas DM
    Clin Cancer Res; 2012 Sep; 18(17):4600-11. PubMed ID: 22791882
    [TBL] [Abstract][Full Text] [Related]  

  • 2. P276-00, a cyclin-dependent kinase inhibitor, modulates cell cycle and induces apoptosis in vitro and in vivo in mantle cell lymphoma cell lines.
    Shirsath NP; Manohar SM; Joshi KS
    Mol Cancer; 2012 Oct; 11():77. PubMed ID: 23075291
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma.
    Beltran E; Fresquet V; Martinez-Useros J; Richter-Larrea JA; Sagardoy A; Sesma I; Almada LL; Montes-Moreno S; Siebert R; Gesk S; Calasanz MJ; Malumbres R; Rieger M; Prosper F; Lossos IS; Piris MA; Fernandez-Zapico ME; Martinez-Climent JA
    Proc Natl Acad Sci U S A; 2011 Jul; 108(30):12461-6. PubMed ID: 21746927
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sorafenib inhibits cell migration and stroma-mediated bortezomib resistance by interfering B-cell receptor signaling and protein translation in mantle cell lymphoma.
    Xargay-Torrent S; López-Guerra M; Montraveta A; Saborit-Villarroya I; Rosich L; Navarro A; Pérez-Galán P; Roué G; Campo E; Colomer D
    Clin Cancer Res; 2013 Feb; 19(3):586-97. PubMed ID: 23231952
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma.
    Yang Q; Chen LS; Neelapu SS; Miranda RN; Medeiros LJ; Gandhi V
    Blood; 2012 Oct; 120(17):3491-500. PubMed ID: 22955922
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FGF9/FGFR2 increase cell proliferation by activating ERK1/2, Rb/E2F1, and cell cycle pathways in mouse Leydig tumor cells.
    Chang MM; Lai MS; Hong SY; Pan BS; Huang H; Yang SH; Wu CC; Sun HS; Chuang JI; Wang CY; Huang BM
    Cancer Sci; 2018 Nov; 109(11):3503-3518. PubMed ID: 30191630
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma.
    Chiarle R; Budel LM; Skolnik J; Frizzera G; Chilosi M; Corato A; Pizzolo G; Magidson J; Montagnoli A; Pagano M; Maes B; De Wolf-Peeters C; Inghirami G
    Blood; 2000 Jan; 95(2):619-26. PubMed ID: 10627471
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes.
    Moros A; Bustany S; Cahu J; Saborit-Villarroya I; Martínez A; Colomer D; Sola B; Roué G
    Clin Cancer Res; 2014 Jan; 20(2):393-403. PubMed ID: 24178620
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclin D1-CDK4 activity drives sensitivity to bortezomib in mantle cell lymphoma by blocking autophagy-mediated proteolysis of NOXA.
    Heine S; Kleih M; Giménez N; Böpple K; Ott G; Colomer D; Aulitzky WE; van der Kuip H; Silkenstedt E
    J Hematol Oncol; 2018 Sep; 11(1):112. PubMed ID: 30180865
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclin D1 depletion induces DNA damage in mantle cell lymphoma lines.
    Mohanty S; Mohanty A; Sandoval N; Tran T; Bedell V; Wu J; Scuto A; Murata-Collins J; Weisenburger DD; Ngo VN
    Leuk Lymphoma; 2017 Mar; 58(3):676-688. PubMed ID: 27338091
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity.
    Marzec M; Kasprzycka M; Lai R; Gladden AB; Wlodarski P; Tomczak E; Nowell P; Deprimo SE; Sadis S; Eck S; Schuster SJ; Diehl JA; Wasik MA
    Blood; 2006 Sep; 108(5):1744-50. PubMed ID: 16690963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell cycle alterations in the blastoid variant of mantle cell lymphoma (MCL-BV) as detected by gene expression profiling of mantle cell lymphoma (MCL) and MCL-BV.
    de Vos S; Krug U; Hofmann WK; Pinkus GS; Swerdlow SH; Wachsman W; Grogan TM; Said JW; Koeffler HP
    Diagn Mol Pathol; 2003 Mar; 12(1):35-43. PubMed ID: 12605034
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HSP90 inhibition downregulates DNA replication and repair genes via E2F1 repression.
    Liu H; Lu Z; Shi X; Liu L; Zhang P; Golemis EA; Tu Z
    J Biol Chem; 2021 Aug; 297(2):100996. PubMed ID: 34302809
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway.
    Li T; Xiong Y; Wang Q; Chen F; Zeng Y; Yu X; Wang Y; Zhou F; Zhou Y
    Artif Cells Nanomed Biotechnol; 2019 Dec; 47(1):4001-4011. PubMed ID: 31588803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combined administration of rituximab and on 013105 induces apoptosis in mantle cell lymphoma cells and reduces tumor burden in a mouse model of mantle cell lymphoma.
    Prasad A; Shrivastava A; Papadopoulos E; Kuzontkoski PM; Reddy MV; Gillum AM; Kumar R; Reddy EP; Groopman JE
    Clin Cancer Res; 2013 Jan; 19(1):85-95. PubMed ID: 23124440
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2.
    Klier M; Anastasov N; Hermann A; Meindl T; Angermeier D; Raffeld M; Fend F; Quintanilla-Martinez L
    Leukemia; 2008 Nov; 22(11):2097-105. PubMed ID: 18685613
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Retinoblastoma (Rb) tumor-suppressor pathway alterations in meningeal hemangiopericytomas: High E2F transcription factor 1 expression and loss of Rb expression: study by double immunofluorescence staining and laser-scanning confocal microscopy.
    Martinez JC; Palomino JC; Samaniego R; Sepulveda JM; Cabello A; Ricoy JR
    Cancer; 2008 Jul; 113(1):166-74. PubMed ID: 18459177
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells.
    Kawamata N; Chen J; Koeffler HP
    Blood; 2007 Oct; 110(7):2667-73. PubMed ID: 17606765
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanism of the antitumoral activity of deferasirox, an iron chelation agent, on mantle cell lymphoma.
    Vazana-Barad L; Granot G; Mor-Tzuntz R; Levi I; Dreyling M; Nathan I; Shpilberg O
    Leuk Lymphoma; 2013 Apr; 54(4):851-9. PubMed ID: 23020673
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Styryl sulfonyl compounds inhibit translation of cyclin D1 in mantle cell lymphoma cells.
    Prasad A; Park IW; Allen H; Zhang X; Reddy MV; Boominathan R; Reddy EP; Groopman JE
    Oncogene; 2009 Mar; 28(12):1518-28. PubMed ID: 19198627
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.