These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 22792139)

  • 1. Overexpression of parkin ameliorates dopaminergic neurodegeneration induced by 1- methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
    Bian M; Liu J; Hong X; Yu M; Huang Y; Sheng Z; Fei J; Huang F
    PLoS One; 2012; 7(6):e39953. PubMed ID: 22792139
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1.
    Haque ME; Mount MP; Safarpour F; Abdel-Messih E; Callaghan S; Mazerolle C; Kitada T; Slack RS; Wallace V; Shen J; Anisman H; Park DS
    J Biol Chem; 2012 Jun; 287(27):23162-70. PubMed ID: 22511790
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cinnamon treatment upregulates neuroprotective proteins Parkin and DJ-1 and protects dopaminergic neurons in a mouse model of Parkinson's disease.
    Khasnavis S; Pahan K
    J Neuroimmune Pharmacol; 2014 Sep; 9(4):569-81. PubMed ID: 24946862
    [TBL] [Abstract][Full Text] [Related]  

  • 4. α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment.
    George S; Mok SS; Nurjono M; Ayton S; Finkelstein DI; Masters CL; Li QX; Culvenor JG
    J Mol Neurosci; 2010 Oct; 42(2):243-54. PubMed ID: 20464527
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DJ-1 and Parkin modulate dopamine-dependent behavior and inhibit MPTP-induced nigral dopamine neuron loss in mice.
    Paterna JC; Leng A; Weber E; Feldon J; Büeler H
    Mol Ther; 2007 Apr; 15(4):698-704. PubMed ID: 17299411
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity.
    Thomas B; von Coelln R; Mandir AS; Trinkaus DB; Farah MH; Leong Lim K; Calingasan NY; Flint Beal M; Dawson VL; Dawson TM
    Neurobiol Dis; 2007 May; 26(2):312-22. PubMed ID: 17336077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice.
    Crocker SJ; Liston P; Anisman H; Lee CJ; Smith PD; Earl N; Thompson CS; Park DS; Korneluk RG; Robertson GS
    Neurobiol Dis; 2003 Mar; 12(2):150-61. PubMed ID: 12667469
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Parkin-knockout mice did not display increased vulnerability to intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Aguiar AS; Tristão FS; Amar M; Chevarin C; Lanfumey L; Mongeau R; Corti O; Prediger RD; Raisman-Vozari R
    Neurotox Res; 2013 Aug; 24(2):280-7. PubMed ID: 23588969
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
    Richter F; Gao F; Medvedeva V; Lee P; Bove N; Fleming SM; Michaud M; Lemesre V; Patassini S; De La Rosa K; Mulligan CK; Sioshansi PC; Zhu C; Coppola G; Bordet T; Pruss RM; Chesselet MF
    Neurobiol Dis; 2014 Sep; 69():263-75. PubMed ID: 24844147
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recovery of hypothalamic tuberoinfundibular dopamine neurons from acute toxicant exposure is dependent upon protein synthesis and associated with an increase in parkin and ubiquitin carboxy-terminal hydrolase-L1 expression.
    Benskey M; Behrouz B; Sunryd J; Pappas SS; Baek SH; Huebner M; Lookingland KJ; Goudreau JL
    Neurotoxicology; 2012 Jun; 33(3):321-31. PubMed ID: 22342763
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease.
    Yasuda T; Hayakawa H; Nihira T; Ren YR; Nakata Y; Nagai M; Hattori N; Miyake K; Takada M; Shimada T; Mizuno Y; Mochizuki H
    J Neuropathol Exp Neurol; 2011 Aug; 70(8):686-97. PubMed ID: 21760537
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinson's disease.
    Hennis MR; Marvin MA; Taylor CM; Goldberg MS
    Neurobiol Dis; 2014 Feb; 62():113-23. PubMed ID: 24075852
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.
    Vila M; Vukosavic S; Jackson-Lewis V; Neystat M; Jakowec M; Przedborski S
    J Neurochem; 2000 Feb; 74(2):721-9. PubMed ID: 10646524
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo.
    Kim HW; Choi WS; Sorscher N; Park HJ; Tronche F; Palmiter RD; Xia Z
    Neurobiol Aging; 2015 Sep; 36(9):2617-27. PubMed ID: 26070241
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Melatonin enhances L-DOPA therapeutic effects, helps to reduce its dose, and protects dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.
    Naskar A; Prabhakar V; Singh R; Dutta D; Mohanakumar KP
    J Pineal Res; 2015 Apr; 58(3):262-74. PubMed ID: 25626558
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
    Wang M; Wan C; He T; Han C; Zhu K; Waddington JL; Zhen X
    Neuropharmacology; 2021 Sep; 196():108360. PubMed ID: 33122030
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nigral overexpression of alpha-synuclein in the absence of parkin enhances alpha-synuclein phosphorylation but does not modulate dopaminergic neurodegeneration.
    Van Rompuy AS; Oliveras-Salvá M; Van der Perren A; Corti O; Van den Haute C; Baekelandt V
    Mol Neurodegener; 2015 Jun; 10():23. PubMed ID: 26099628
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sensitivity to MPTP is not increased in Parkinson's disease-associated mutant alpha-synuclein transgenic mice.
    Rathke-Hartlieb S; Kahle PJ; Neumann M; Ozmen L; Haid S; Okochi M; Haass C; Schulz JB
    J Neurochem; 2001 May; 77(4):1181-4. PubMed ID: 11359883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Behavioral and neurotransmitter abnormalities in mice deficient for Parkin, DJ-1 and superoxide dismutase.
    Hennis MR; Seamans KW; Marvin MA; Casey BH; Goldberg MS
    PLoS One; 2013; 8(12):e84894. PubMed ID: 24386432
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein.
    Lu XH; Fleming SM; Meurers B; Ackerson LC; Mortazavi F; Lo V; Hernandez D; Sulzer D; Jackson GR; Maidment NT; Chesselet MF; Yang XW
    J Neurosci; 2009 Feb; 29(7):1962-76. PubMed ID: 19228951
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.