BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 22795132)

  • 1. A class of allosteric caspase inhibitors identified by high-throughput screening.
    Feldman T; Kabaleeswaran V; Jang SB; Antczak C; Djaballah H; Wu H; Jiang X
    Mol Cell; 2012 Aug; 47(4):585-95. PubMed ID: 22795132
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases.
    Dagbay K; Eron SJ; Serrano BP; Velázquez-Delgado EM; Zhao Y; Lin D; Vaidya S; Hardy JA
    Methods Enzymol; 2014; 544():215-49. PubMed ID: 24974292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of caspase-9 by stabilized peptides targeting the dimerization interface.
    Huber KL; Ghosh S; Hardy JA
    Biopolymers; 2012; 98(5):451-65. PubMed ID: 23203690
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of FDA-approved drugs as novel allosteric inhibitors of human executioner caspases.
    Krishna Deepak RNV; Abdullah A; Talwar P; Fan H; Ravanan P
    Proteins; 2018 Nov; 86(11):1202-1210. PubMed ID: 30194780
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of Allosteric Inhibitors against Active Caspase-6.
    Tubeleviciute-Aydin A; Beautrait A; Lynham J; Sharma G; Gorelik A; Deny LJ; Soya N; Lukacs GL; Nagar B; Marinier A; LeBlanc AC
    Sci Rep; 2019 Apr; 9(1):5504. PubMed ID: 30940883
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism of XIAP-mediated inhibition of caspase-9.
    Shiozaki EN; Chai J; Rigotti DJ; Riedl SJ; Li P; Srinivasula SM; Alnemri ES; Fairman R; Shi Y
    Mol Cell; 2003 Feb; 11(2):519-27. PubMed ID: 12620238
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6.
    Heise CE; Murray J; Augustyn KE; Bravo B; Chugha P; Cohen F; Giannetti AM; Gibbons P; Hannoush RN; Hearn BR; Jaishankar P; Ly CQ; Shah K; Stanger K; Steffek M; Tang Y; Zhao X; Lewcock JW; Renslo AR; Flygare J; Arkin MR
    PLoS One; 2012; 7(12):e50864. PubMed ID: 23227217
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of specific tethered inhibitors for caspase-5.
    Gao J; Wells JA
    Chem Biol Drug Des; 2012 Feb; 79(2):209-15. PubMed ID: 22014003
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.
    Smith CE; Soti S; Jones TA; Nakagawa A; Xue D; Yin H
    Cell Chem Biol; 2017 Mar; 24(3):281-292. PubMed ID: 28238723
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A common allosteric site and mechanism in caspases.
    Scheer JM; Romanowski MJ; Wells JA
    Proc Natl Acad Sci U S A; 2006 May; 103(20):7595-600. PubMed ID: 16682620
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The atomic-resolution structure of human caspase-8, a key activator of apoptosis.
    Watt W; Koeplinger KA; Mildner AM; Heinrikson RL; Tomasselli AG; Watenpaugh KD
    Structure; 1999 Sep; 7(9):1135-43. PubMed ID: 10508785
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytoprotective effect of selective small-molecule caspase inhibitors against staurosporine-induced apoptosis.
    Wu J; Wang Y; Liang S; Ma H
    Drug Des Devel Ther; 2014; 8():583-600. PubMed ID: 24920883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of small molecule inhibitors for the C. elegans caspase CED-3 by high-throughput screening.
    Brantley SJ; Cotten SW; Lamson DR; Smith GR; Liu R; Williams KP
    Biochem Biophys Res Commun; 2017 Sep; 491(3):773-779. PubMed ID: 28733033
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific inhibition of caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors.
    Schroeder T; Barandun J; Flütsch A; Briand C; Mittl PR; Grütter MG
    Structure; 2013 Feb; 21(2):277-89. PubMed ID: 23333429
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening.
    Joseph J; Seervi M; Sobhan PK; Retnabai ST
    PLoS One; 2011; 6(5):e20114. PubMed ID: 21637712
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP.
    Vucic D; Franklin MC; Wallweber HJ; Das K; Eckelman BP; Shin H; Elliott LO; Kadkhodayan S; Deshayes K; Salvesen GS; Fairbrother WJ
    Biochem J; 2005 Jan; 385(Pt 1):11-20. PubMed ID: 15485396
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small Molecule Active Site Directed Tools for Studying Human Caspases.
    Poreba M; Szalek A; Kasperkiewicz P; Rut W; Salvesen GS; Drag M
    Chem Rev; 2015 Nov; 115(22):12546-629. PubMed ID: 26551511
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis.
    Blanchard H; Kodandapani L; Mittl PR; Marco SD; Krebs JF; Wu JC; Tomaselli KJ; Grütter MG
    Structure; 1999 Sep; 7(9):1125-33. PubMed ID: 10508784
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of an allosteric site in the caspases.
    Hardy JA; Lam J; Nguyen JT; O'Brien T; Wells JA
    Proc Natl Acad Sci U S A; 2004 Aug; 101(34):12461-6. PubMed ID: 15314233
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Live-cell imaging of caspase activation for high-content screening.
    Antczak C; Takagi T; Ramirez CN; Radu C; Djaballah H
    J Biomol Screen; 2009 Sep; 14(8):956-69. PubMed ID: 19726787
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.