These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 22795332)

  • 1. Optimisation of imidazole compounds as selective TAAR1 agonists: discovery of RO5073012.
    Galley G; Stalder H; Goergler A; Hoener MC; Norcross RD
    Bioorg Med Chem Lett; 2012 Aug; 22(16):5244-8. PubMed ID: 22795332
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery and SAR development of 2-(phenylamino) imidazolines as prostacyclin receptor antagonists [corrected].
    Clark RD; Jahangir A; Severance D; Salazar R; Chang T; Chang D; Jett MF; Smith S; Bley K
    Bioorg Med Chem Lett; 2004 Feb; 14(4):1053-6. PubMed ID: 15013022
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators.
    Gerlach K; Hobson S; Eickmeier C; Groß U; Braun C; Sieger P; Garneau M; Hoerer S; Heine N
    Bioorg Med Chem; 2018 Jul; 26(12):3227-3241. PubMed ID: 29735425
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and structure-activity-relationship of phenyl imidazoles as potent Smoothened antagonists.
    Cheng D; Han D; Gao W; Jing Q; Jiang J; Wan Y; Englund NP; Tuntland T; Wu X; Pan S
    Bioorg Med Chem Lett; 2012 Nov; 22(21):6573-6. PubMed ID: 23036954
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery and optimization of arylsulfonyl 3-(pyridin-2-yloxy)anilines as novel GPR119 agonists.
    Zhang JK; Li AR; Yu M; Wang Y; Zhu J; Kayser F; Medina JC; Siegler K; Conn M; Shan B; Grillo MP; Eksterowicz J; Coward P; Liu JJ
    Bioorg Med Chem Lett; 2013 Jun; 23(12):3609-13. PubMed ID: 23648181
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacologic characterization of the cloned human trace amine-associated receptor1 (TAAR1) and evidence for species differences with the rat TAAR1.
    Wainscott DB; Little SP; Yin T; Tu Y; Rocco VP; He JX; Nelson DL
    J Pharmacol Exp Ther; 2007 Jan; 320(1):475-85. PubMed ID: 17038507
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics.
    Revel FG; Moreau JL; Gainetdinov RR; Ferragud A; Velázquez-Sánchez C; Sotnikova TD; Morairty SR; Harmeier A; Groebke Zbinden K; Norcross RD; Bradaia A; Kilduff TS; Biemans B; Pouzet B; Caron MG; Canales JJ; Wallace TL; Wettstein JG; Hoener MC
    Biol Psychiatry; 2012 Dec; 72(11):934-42. PubMed ID: 22705041
    [TBL] [Abstract][Full Text] [Related]  

  • 8. N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists.
    Menghin S; Pertz HH; Kramer K; Seifert R; Schunack W; Elz S
    J Med Chem; 2003 Dec; 46(25):5458-70. PubMed ID: 14640554
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligands.
    Kottke T; Sander K; Weizel L; Schneider EH; Seifert R; Stark H
    Eur J Pharmacol; 2011 Mar; 654(3):200-8. PubMed ID: 21237145
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and evaluation of 1-benzyl-1H-imidazole-5-carboxamide derivatives as potent TGR5 agonists.
    Zhao S; Li X; Wang L; Peng W; Ye W; Li W; Wang YD; Chen WD
    Bioorg Med Chem; 2021 Feb; 32():115972. PubMed ID: 33440321
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E
    Muthukaman N; Tambe M; Shaikh M; Pisal D; Deshmukh S; Tondlekar S; Sarode N; Narayana L; Gajera JM; Kattige VG; Honnegowda S; Karande V; Kulkarni A; Behera D; Jadhav SB; Gudi GS; Khairatkar-Joshi N; Gharat LA
    Bioorg Med Chem Lett; 2017 Jun; 27(11):2594-2601. PubMed ID: 28400234
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
    Tonelli M; Espinoza S; Gainetdinov RR; Cichero E
    Eur J Med Chem; 2017 Feb; 127():781-792. PubMed ID: 27823885
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alpha(1)-adrenoceptor activation: a comparison of 4-(anilinomethyl)imidazoles and 4-(phenoxymethyl)imidazoles to related 2-imidazolines.
    Hodson SJ; Bigham EC; Garrison DT; Gobel MJ; Irving PE; Liacos JA; Navas F; Saussy DL; Sherman BW; Speake JD; Bishop MJ
    Bioorg Med Chem Lett; 2002 Dec; 12(23):3449-52. PubMed ID: 12419381
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series.
    Barlaam B; Ducray R; Lambert-van der Brempt C; Plé P; Bardelle C; Brooks N; Coleman T; Cross D; Kettle JG; Read J
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2207-11. PubMed ID: 21441027
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of the imidazole-derived GPR40 agonist AM-3189.
    Ma Z; Lin DC; Sharma R; Liu J; Zhu L; Li AR; Kohn T; Wang Y; Liu JJ; Bartberger MD; Medina JC; Zhuang R; Li F; Zhang J; Luo J; Wong S; Tonn GR; Houze JB
    Bioorg Med Chem Lett; 2016 Jan; 26(1):15-20. PubMed ID: 26620255
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of trace amine-associated receptor 1 attenuates schedule-induced polydipsia in rats.
    Sukhanov I; Dorotenko A; Dolgorukova A; Hoener MC; Gainetdinov RR; Bespalov AY
    Neuropharmacology; 2019 Jan; 144():184-192. PubMed ID: 30366004
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of potent and selective small-molecule human Urotensin-II antagonists.
    McAtee JJ; Dodson JW; Dowdell SE; Girard GR; Goodman KB; Hilfiker MA; Sehon CA; Sha D; Wang GZ; Wang N; Viet AQ; Zhang D; Aiyar NV; Behm DJ; Carballo LH; Evans CA; Fries HE; Nagilla R; Roethke TJ; Xu X; Yuan CC; Douglas SA; Neeb MJ
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3500-3. PubMed ID: 18502123
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective antagonists of mouse trace amine-associated receptor 1 (mTAAR1): discovery of EPPTB (RO5212773).
    Stalder H; Hoener MC; Norcross RD
    Bioorg Med Chem Lett; 2011 Feb; 21(4):1227-31. PubMed ID: 21237643
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trace Amine-Associated Receptor 1 Agonists as Narcolepsy Therapeutics.
    Black SW; Schwartz MD; Chen TM; Hoener MC; Kilduff TS
    Biol Psychiatry; 2017 Nov; 82(9):623-633. PubMed ID: 27919403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain.
    Yang SW; Smotryski J; Matasi J; Ho G; Tulshian D; Greenlee WJ; Brusa R; Beltramo M; Cox K
    Bioorg Med Chem Lett; 2011 Jan; 21(1):182-5. PubMed ID: 21115245
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.